Lefkowitz RJ - Search Results

1

Regulation of membrane targeting of the G protein-coupled receptor kinase 2 by protein kinase A and its anchoring protein AKAP79.

Cong M, Perry SJ, Lin FT, Fraser ID, Hu LA, Chen W, Pitcher JA, Scott JD, Lefkowitz RJ. Cong M, et al. Among authors: lefkowitz rj. J Biol Chem. 2001 May 4;276(18):15192-9. doi: 10.1074/jbc.M009130200. Epub 2001 Jan 22. J Biol Chem. 2001. PMID: 11278469 Free article.

2

Discrete amino acid sequences of the alpha 1-adrenergic receptor determine the selectivity of coupling to phosphatidylinositol hydrolysis.

Cotecchia S, Ostrowski J, Kjelsberg MA, Caron MG, Lefkowitz RJ. Cotecchia S, et al. Among authors: lefkowitz rj. J Biol Chem. 1992 Jan 25;267(3):1633-9. J Biol Chem. 1992. PMID: 1309789 Free article.

3

Sites in the third intracellular loop of the alpha 2A-adrenergic receptor confer short term agonist-promoted desensitization. Evidence for a receptor kinase-mediated mechanism.

Liggett SB, Ostrowski J, Chesnut LC, Kurose H, Raymond JR, Caron MG, Lefkowitz RJ. Liggett SB, et al. Among authors: lefkowitz rj. J Biol Chem. 1992 Mar 5;267(7):4740-6. J Biol Chem. 1992. PMID: 1311318 Free article.

4

From ligand binding to gene expression: new insights into the regulation of G-protein-coupled receptors.

Collins S, Caron MG, Lefkowitz RJ. Collins S, et al. Among authors: lefkowitz rj. Trends Biochem Sci. 1992 Jan;17(1):37-9. doi: 10.1016/0968-0004(92)90425-9. Trends Biochem Sci. 1992. PMID: 1316650 Review.

5

Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors.

Pitcher JA, Inglese J, Higgins JB, Arriza JL, Casey PJ, Kim C, Benovic JL, Kwatra MM, Caron MG, Lefkowitz RJ. Pitcher JA, et al. Among authors: lefkowitz rj. Science. 1992 Aug 28;257(5074):1264-7. doi: 10.1126/science.1325672. Science. 1992. PMID: 1325672

6

G-protein-coupled receptors: regulatory role of receptor kinases and arrestin proteins.

Lefkowitz RJ, Inglese J, Koch WJ, Pitcher J, Attramadal H, Caron MG. Lefkowitz RJ, et al. Cold Spring Harb Symp Quant Biol. 1992;57:127-33. doi: 10.1101/sqb.1992.057.01.016. Cold Spring Harb Symp Quant Biol. 1992. PMID: 1339651 Review. No abstract available.

7

Constitutive activation of the alpha 1B-adrenergic receptor by all amino acid substitutions at a single site. Evidence for a region which constrains receptor activation.

Kjelsberg MA, Cotecchia S, Ostrowski J, Caron MG, Lefkowitz RJ. Kjelsberg MA, et al. Among authors: lefkowitz rj. J Biol Chem. 1992 Jan 25;267(3):1430-3. J Biol Chem. 1992. PMID: 1346134 Free article.

8

Desensitization of the isolated beta 2-adrenergic receptor by beta-adrenergic receptor kinase, cAMP-dependent protein kinase, and protein kinase C occurs via distinct molecular mechanisms.

Pitcher J, Lohse MJ, Codina J, Caron MG, Lefkowitz RJ. Pitcher J, et al. Among authors: lefkowitz rj. Biochemistry. 1992 Mar 31;31(12):3193-7. doi: 10.1021/bi00127a021. Biochemistry. 1992. PMID: 1348186

9

Receptor-specific desensitization with purified proteins. Kinase dependence and receptor specificity of beta-arrestin and arrestin in the beta 2-adrenergic receptor and rhodopsin systems.

Lohse MJ, Andexinger S, Pitcher J, Trukawinski S, Codina J, Faure JP, Caron MG, Lefkowitz RJ. Lohse MJ, et al. Among authors: lefkowitz rj. J Biol Chem. 1992 Apr 25;267(12):8558-64. J Biol Chem. 1992. PMID: 1349018 Free article.

10

Tyrosine phosphorylation of G protein alpha subunits by pp60c-src.

Hausdorff WP, Pitcher JA, Luttrell DK, Linder ME, Kurose H, Parsons SJ, Caron MG, Lefkowitz RJ. Hausdorff WP, et al. Among authors: lefkowitz rj. Proc Natl Acad Sci U S A. 1992 Jul 1;89(13):5720-4. doi: 10.1073/pnas.89.13.5720. Proc Natl Acad Sci U S A. 1992. PMID: 1378615 Free PMC article.

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