Polonsky K - Search Results

1

Dysregulation of insulin secretion in children with congenital hyperinsulinism due to sulfonylurea receptor mutations.

Grimberg A, Ferry RJ Jr, Kelly A, Koo-McCoy S, Polonsky K, Glaser B, Permutt MA, Aguilar-Bryan L, Stafford D, Thornton PS, Baker L, Stanley CA. Grimberg A, et al. Among authors: polonsky k. Diabetes. 2001 Feb;50(2):322-8. doi: 10.2337/diabetes.50.2.322. Diabetes. 2001. PMID: 11272143 Free PMC article.

2

Reduced expression of the insulin receptor in mouse insulinoma (MIN6) cells reveals multiple roles of insulin signaling in gene expression, proliferation, insulin content, and secretion.

Ohsugi M, Cras-Méneur C, Zhou Y, Bernal-Mizrachi E, Johnson JD, Luciani DS, Polonsky KS, Permutt MA. Ohsugi M, et al. J Biol Chem. 2005 Feb 11;280(6):4992-5003. doi: 10.1074/jbc.M411727200. Epub 2004 Nov 15. J Biol Chem. 2005. PMID: 15546857 Free article.

3

Failure of physiological plasma glucose excursions to entrain high-frequency pulsatile insulin secretion in type 2 diabetes.

Hollingdal M, Juhl CB, Pincus SM, Sturis J, Veldhuis JD, Polonsky KS, Pørksen N, Schmitz O. Hollingdal M, et al. Among authors: polonsky ks. Diabetes. 2000 Aug;49(8):1334-40. doi: 10.2337/diabetes.49.8.1334. Diabetes. 2000. PMID: 10923634 Clinical Trial.

4

Defective insulin secretion and increased susceptibility to experimental diabetes are induced by reduced Akt activity in pancreatic islet beta cells.

Bernal-Mizrachi E, Fatrai S, Johnson JD, Ohsugi M, Otani K, Han Z, Polonsky KS, Permutt MA. Bernal-Mizrachi E, et al. Among authors: polonsky ks. J Clin Invest. 2004 Oct;114(7):928-36. doi: 10.1172/JCI20016. J Clin Invest. 2004. PMID: 15467831 Free PMC article.

5

Kir6.2 variant E23K increases ATP-sensitive K+ channel activity and is associated with impaired insulin release and enhanced insulin sensitivity in adults with normal glucose tolerance.

Villareal DT, Koster JC, Robertson H, Akrouh A, Miyake K, Bell GI, Patterson BW, Nichols CG, Polonsky KS. Villareal DT, et al. Among authors: polonsky ks. Diabetes. 2009 Aug;58(8):1869-78. doi: 10.2337/db09-0025. Epub 2009 Jun 2. Diabetes. 2009. PMID: 19491206 Free PMC article.

6

Insulin secretion and clearance. Comparison after oral and intravenous glucose.

Shapiro ET, Tillil H, Miller MA, Frank BH, Galloway JA, Rubenstein AH, Polonsky KS. Shapiro ET, et al. Among authors: polonsky ks. Diabetes. 1987 Dec;36(12):1365-71. doi: 10.2337/diab.36.12.1365. Diabetes. 1987. PMID: 3315785

7

Xenin-25 amplifies GIP-mediated insulin secretion in humans with normal and impaired glucose tolerance but not type 2 diabetes.

Wice BM, Reeds DN, Tran HD, Crimmins DL, Patterson BW, Dunai J, Wallendorf MJ, Ladenson JH, Villareal DT, Polonsky KS. Wice BM, et al. Diabetes. 2012 Jul;61(7):1793-800. doi: 10.2337/db11-1451. Epub 2012 Apr 20. Diabetes. 2012. PMID: 22522617 Free PMC article. Clinical Trial.

8

Altered insulin secretory responses to glucose in diabetic and nondiabetic subjects with mutations in the diabetes susceptibility gene MODY3 on chromosome 12.

Byrne MM, Sturis J, Menzel S, Yamagata K, Fajans SS, Dronsfield MJ, Bain SC, Hattersley AT, Velho G, Froguel P, Bell GI, Polonsky KS. Byrne MM, et al. Among authors: polonsky ks. Diabetes. 1996 Nov;45(11):1503-10. doi: 10.2337/diab.45.11.1503. Diabetes. 1996. PMID: 8866553

9

Rosiglitazone reduces glucose-stimulated insulin secretion rate and increases insulin clearance in nondiabetic, insulin-resistant individuals.

Kim SH, Abbasi F, Chu JW, McLaughlin TL, Lamendola C, Polonsky KS, Reaven GM. Kim SH, et al. Diabetes. 2005 Aug;54(8):2447-52. doi: 10.2337/diabetes.54.8.2447. Diabetes. 2005. PMID: 16046313

10

Alterations in the patterns of insulin secretion before and after diagnosis of IDDM.

O'Meara NM, Sturis J, Herold KC, Ostrega DM, Polonsky KS. O'Meara NM, et al. Among authors: polonsky ks. Diabetes Care. 1995 Apr;18(4):568-71. doi: 10.2337/diacare.18.4.568. Diabetes Care. 1995. PMID: 7497873

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