Johns A - Search Results

1

SB-334867-A: the first selective orexin-1 receptor antagonist.

Smart D, Sabido-David C, Brough SJ, Jewitt F, Johns A, Porter RA, Jerman JC. Smart D, et al. Among authors: johns a. Br J Pharmacol. 2001 Mar;132(6):1179-82. doi: 10.1038/sj.bjp.0703953. Br J Pharmacol. 2001. PMID: 11250867 Free PMC article.

2

Evidence that orexin-A-evoked grooming in the rat is mediated by orexin-1 (OX1) receptors, with downstream 5-HT2C receptor involvement.

Duxon MS, Stretton J, Starr K, Jones DN, Holland V, Riley G, Jerman J, Brough S, Smart D, Johns A, Chan W, Porter RA, Upton N. Duxon MS, et al. Among authors: johns a. Psychopharmacology (Berl). 2001 Jan 1;153(2):203-9. doi: 10.1007/s002130000550. Psychopharmacology (Berl). 2001. PMID: 11205420

3

1,3-Biarylureas as selective non-peptide antagonists of the orexin-1 receptor.

Porter RA, Chan WN, Coulton S, Johns A, Hadley MS, Widdowson K, Jerman JC, Brough SJ, Coldwell M, Smart D, Jewitt F, Jeffrey P, Austin N. Porter RA, et al. Among authors: johns a. Bioorg Med Chem Lett. 2001 Jul 23;11(14):1907-10. doi: 10.1016/s0960-894x(01)00343-2. Bioorg Med Chem Lett. 2001. PMID: 11459658

4

A selective orexin-1 receptor antagonist reduces food consumption in male and female rats.

Haynes AC, Jackson B, Chapman H, Tadayyon M, Johns A, Porter RA, Arch JR. Haynes AC, et al. Among authors: johns a. Regul Pept. 2000 Dec 22;96(1-2):45-51. doi: 10.1016/s0167-0115(00)00199-3. Regul Pept. 2000. PMID: 11102651

5

Effects of centrally administered orexin-B and orexin-A: a role for orexin-1 receptors in orexin-B-induced hyperactivity.

Jones DN, Gartlon J, Parker F, Taylor SG, Routledge C, Hemmati P, Munton RP, Ashmeade TE, Hatcher JP, Johns A, Porter RA, Hagan JJ, Hunter AJ, Upton N. Jones DN, et al. Among authors: johns a. Psychopharmacology (Berl). 2001 Jan 1;153(2):210-8. doi: 10.1007/s002130000551. Psychopharmacology (Berl). 2001. PMID: 11205421

6

SB-334867, a selective orexin-1 receptor antagonist, enhances behavioural satiety and blocks the hyperphagic effect of orexin-A in rats.

Rodgers RJ, Halford JC, Nunes de Souza RL, Canto de Souza AL, Piper DC, Arch JR, Upton N, Porter RA, Johns A, Blundell JE. Rodgers RJ, et al. Among authors: johns a. Eur J Neurosci. 2001 Apr;13(7):1444-52. doi: 10.1046/j.0953-816x.2001.01518.x. Eur J Neurosci. 2001. PMID: 11298806

7

Orexin-A, an hypothalamic peptide with analgesic properties.

Bingham S, Davey PT, Babbs AJ, Irving EA, Sammons MJ, Wyles M, Jeffrey P, Cutler L, Riba I, Johns A, Porter RA, Upton N, Hunter AJ, Parsons AA. Bingham S, et al. Among authors: johns a. Pain. 2001 May;92(1-2):81-90. doi: 10.1016/s0304-3959(00)00470-x. Pain. 2001. PMID: 11323129

8

Satiety enhancement by selective orexin-1 receptor antagonist SB-334867: influence of test context and profile comparison with CCK-8S.

Ishii Y, Blundell JE, Halford JC, Upton N, Porter R, Johns A, Rodgers RJ. Ishii Y, et al. Among authors: johns a. Behav Brain Res. 2005 May 7;160(1):11-24. doi: 10.1016/j.bbr.2004.11.011. Epub 2004 Dec 18. Behav Brain Res. 2005. PMID: 15836896

9

Differential effects of the selective orexin-1 receptor antagonist SB-334867 and lithium chloride on the behavioural satiety sequence in rats.

Ishii Y, Blundell JE, Halford JC, Upton N, Porter R, Johns A, Rodgers RJ. Ishii Y, et al. Among authors: johns a. Physiol Behav. 2004 Mar;81(1):129-40. doi: 10.1016/j.physbeh.2004.01.009. Physiol Behav. 2004. PMID: 15059692

10

Anorexia and weight loss in male rats 24 h following single dose treatment with orexin-1 receptor antagonist SB-334867.

Ishii Y, Blundell JE, Halford JC, Upton N, Porter R, Johns A, Jeffrey P, Summerfield S, Rodgers RJ. Ishii Y, et al. Among authors: johns a. Behav Brain Res. 2005 Feb 28;157(2):331-41. doi: 10.1016/j.bbr.2004.07.012. Behav Brain Res. 2005. PMID: 15639184

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