Wyvratt MJ - Search Results

1

SAR studies of novel 5-substituted 2-arylindoles as nonpeptidyl GnRH receptor antagonists.

Chu L, Lo JL, Yang YT, Cheng K, Smith RG, Fisher MH, Wyvratt MJ, Goulet MT. Chu L, et al. Among authors: wyvratt mj. Bioorg Med Chem Lett. 2001 Feb 26;11(4):515-7. doi: 10.1016/s0960-894x(00)00708-3. Bioorg Med Chem Lett. 2001. PMID: 11229760

2

A potent, orally bioavailable benzazepinone growth hormone secretagogue.

DeVita RJ, Bochis R, Frontier AJ, Kotliar A, Fisher MH, Schoen WR, Wyvratt MJ, Cheng K, Chan WW, Butler B, Jacks TM, Hickey GJ, Schleim KD, Leung K, Chen Z, Chiu SL, Feeney WP, Cunningham PK, Smith RG. DeVita RJ, et al. Among authors: wyvratt mj. J Med Chem. 1998 May 7;41(10):1716-28. doi: 10.1021/jm970816j. J Med Chem. 1998. PMID: 9572898

3

Potent, selective benzenesulfonamide agonists of the human beta 3 adrenergic receptor.

Weber AE, Mathvink RJ, Perkins L, Hutchins JE, Candelore MR, Tota L, Strader CD, Wyvratt MJ, Fisher MH. Weber AE, et al. Among authors: wyvratt mj. Bioorg Med Chem Lett. 1998 May 5;8(9):1101-6. doi: 10.1016/s0960-894x(98)00169-3. Bioorg Med Chem Lett. 1998. PMID: 9871716

4

Discovery of L-755,507: a subnanomolar human beta 3 adrenergic receptor agonist.

Parmee ER, Ok HO, Candelore MR, Tota L, Deng L, Strader CD, Wyvratt MJ, Fisher MH, Weber AE. Parmee ER, et al. Among authors: wyvratt mj. Bioorg Med Chem Lett. 1998 May 5;8(9):1107-12. doi: 10.1016/s0960-894x(98)00170-x. Bioorg Med Chem Lett. 1998. PMID: 9871717

5

Potent, elective human beta3 adrenergic receptor agonists containing a substituted indoline-5-sulfonamide pharmacophore.

Mathvink RJ, Barritta AM, Candelore MR, Cascieri MA, Deng L, Tota L, Strader CD, Wyvratt MJ, Fisher MH, Weber AE. Mathvink RJ, et al. Among authors: wyvratt mj. Bioorg Med Chem Lett. 1999 Jul 5;9(13):1869-74. doi: 10.1016/s0960-894x(99)00277-2. Bioorg Med Chem Lett. 1999. PMID: 10406657

6

C32-O-phenalkyl ether derivatives of the immunosuppressant ascomycin: a tether length study.

Goulet MT, Sinclair PJ, Wong F, Staruch MJ, Dumont FJ, Cryan JG, Wiederrecht GJ, Wyvratt MJ, Parsons WH. Goulet MT, et al. Among authors: wyvratt mj. Bioorg Med Chem Lett. 1999 Jul 19;9(14):2085-8. doi: 10.1016/s0960-894x(99)00335-2. Bioorg Med Chem Lett. 1999. PMID: 10450986

7

Potent immunosuppressive C32-O-arylethyl ether derivatives of ascomycin with reduced toxicity.

Armstrong HM, Wong F, Holmes MA, Sinclair PJ, Goulet MT, Dumont FJ, Staruch MJ, Koprak S, Peterson LB, Rosa R, Wilusz MB, Wiederrecht GJ, Cryan JG, Wyvratt MJ, Parsons WH. Armstrong HM, et al. Among authors: wyvratt mj. Bioorg Med Chem Lett. 1999 Jul 19;9(14):2089-94. doi: 10.1016/s0960-894x(99)00336-4. Bioorg Med Chem Lett. 1999. PMID: 10450987

8

Identification and initial structure-activity relationships of a novel non-peptide quinolone GnRH receptor antagonist.

DeVita RJ, Hollings DD, Goulet MT, Wyvratt MJ, Fisher MH, Lo JL, Yang YT, Cheng K, Smith RG. DeVita RJ, et al. Among authors: wyvratt mj. Bioorg Med Chem Lett. 1999 Sep 6;9(17):2615-20. doi: 10.1016/s0960-894x(99)00446-1. Bioorg Med Chem Lett. 1999. PMID: 10498220

9

Investigation of the 4-O-alkylamine substituent of non-peptide quinolone GnRH receptor antagonists.

DeVita RJ, Goulet MT, Wyvratt MJ, Fisher MH, Lo JL, Yang YT, Cheng K, Smith RG. DeVita RJ, et al. Among authors: wyvratt mj. Bioorg Med Chem Lett. 1999 Sep 6;9(17):2621-4. doi: 10.1016/s0960-894x(99)00447-3. Bioorg Med Chem Lett. 1999. PMID: 10498221

10

Acyclic structural variants of growth hormone secretagogue L-692,429.

Lin P, Pisano JM, Schoen WR, Cheng K, Chan WW, Butler BS, Smith RG, Fisher MH, Wyvratt MJ. Lin P, et al. Among authors: wyvratt mj. Bioorg Med Chem Lett. 1999 Nov 15;9(22):3237-42. doi: 10.1016/s0960-894x(99)00568-5. Bioorg Med Chem Lett. 1999. PMID: 10576695

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