Conley PB - Search Results

1

Identification of the platelet ADP receptor targeted by antithrombotic drugs.

Hollopeter G, Jantzen HM, Vincent D, Li G, England L, Ramakrishnan V, Yang RB, Nurden P, Nurden A, Julius D, Conley PB. Hollopeter G, et al. Among authors: conley pb. Nature. 2001 Jan 11;409(6817):202-7. doi: 10.1038/35051599. Nature. 2001. PMID: 11196645

2

Evidence for two distinct G-protein-coupled ADP receptors mediating platelet activation.

Jantzen HM, Gousset L, Bhaskar V, Vincent D, Tai A, Reynolds EE, Conley PB. Jantzen HM, et al. Among authors: conley pb. Thromb Haemost. 1999 Jan;81(1):111-7. Thromb Haemost. 1999. PMID: 10348701

3

Novel tricyclic benzothiazolo[2,3-c]thiadiazine antagonists of the platelet ADP receptor (P2Y(12)).

Scarborough RM, Laibelman AM, Clizbe LA, Fretto LJ, Conley PB, Reynolds EE, Sedlock DM, Jantzen H. Scarborough RM, et al. Among authors: conley pb. Bioorg Med Chem Lett. 2001 Jul 23;11(14):1805-8. doi: 10.1016/s0960-894x(01)00313-4. Bioorg Med Chem Lett. 2001. PMID: 11459636

4

Impaired activation of murine platelets lacking G alpha(i2).

Jantzen HM, Milstone DS, Gousset L, Conley PB, Mortensen RM. Jantzen HM, et al. Among authors: conley pb. J Clin Invest. 2001 Aug;108(3):477-83. doi: 10.1172/JCI12818. J Clin Invest. 2001. PMID: 11489941 Free PMC article.

5

P2Y12 regulates platelet adhesion/activation, thrombus growth, and thrombus stability in injured arteries.

Andre P, Delaney SM, LaRocca T, Vincent D, DeGuzman F, Jurek M, Koller B, Phillips DR, Conley PB. Andre P, et al. Among authors: conley pb. J Clin Invest. 2003 Aug;112(3):398-406. doi: 10.1172/JCI17864. J Clin Invest. 2003. PMID: 12897207 Free PMC article.

6

Anticoagulants (thrombin inhibitors) and aspirin synergize with P2Y12 receptor antagonism in thrombosis.

André P, LaRocca T, Delaney SM, Lin PH, Vincent D, Sinha U, Conley PB, Phillips DR. André P, et al. Among authors: conley pb. Circulation. 2003 Nov 25;108(21):2697-703. doi: 10.1161/01.CIR.0000093279.36628.12. Epub 2003 Nov 3. Circulation. 2003. PMID: 14597584

7

Immunolocalization of P2Y1 and TPalpha receptors in platelets showed a major pool associated with the membranes of alpha -granules and the open canalicular system.

Nurden P, Poujol C, Winckler J, Combrié R, Pousseau N, Conley PB, Levy-Toledano S, Habib A, Nurden AT. Nurden P, et al. Among authors: conley pb. Blood. 2003 Feb 15;101(4):1400-8. doi: 10.1182/blood-2002-02-0642. Epub 2002 Oct 10. Blood. 2003. PMID: 12393588 Free article.

8

Scientific and therapeutic insights into the role of the platelet P2Y12 receptor in thrombosis.

Conley PB, Delaney SM. Conley PB, et al. Curr Opin Hematol. 2003 Sep;10(5):333-8. doi: 10.1097/00062752-200309000-00002. Curr Opin Hematol. 2003. PMID: 12913786 Review.

9

Distinct roles for protein kinase C isoforms in regulating platelet purinergic receptor function.

Mundell SJ, Jones ML, Hardy AR, Barton JF, Beaucourt SM, Conley PB, Poole AW. Mundell SJ, et al. Among authors: conley pb. Mol Pharmacol. 2006 Sep;70(3):1132-42. doi: 10.1124/mol.106.023549. Epub 2006 Jun 27. Mol Pharmacol. 2006. PMID: 16804093

10

A clopidogrel-insensitive inducible pool of P2Y12 receptors contributes to thrombus formation: inhibition by elinogrel, a direct-acting, reversible P2Y12 antagonist.

Haberstock-Debic H, Andre P, Mills S, Phillips DR, Conley PB. Haberstock-Debic H, et al. Among authors: conley pb. J Pharmacol Exp Ther. 2011 Oct;339(1):54-61. doi: 10.1124/jpet.111.184143. Epub 2011 Jul 5. J Pharmacol Exp Ther. 2011. PMID: 21730013

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