Hakem R - Search Results

1

Executionary pathway for apoptosis: lessons from mutant mice.

Woo M, Hakem R, Mak TW. Woo M, et al. Among authors: hakem r. Cell Res. 2000 Dec;10(4):267-78. doi: 10.1038/sj.cr.7290054. Cell Res. 2000. PMID: 11191349 Review.

2

The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse.

Hakem R, de la Pompa JL, Sirard C, Mo R, Woo M, Hakem A, Wakeham A, Potter J, Reitmair A, Billia F, Firpo E, Hui CC, Roberts J, Rossant J, Mak TW. Hakem R, et al. Among authors: hakem a. Cell. 1996 Jun 28;85(7):1009-23. doi: 10.1016/s0092-8674(00)81302-1. Cell. 1996. PMID: 8674108 Free article.

3

Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes.

Woo M, Hakem R, Soengas MS, Duncan GS, Shahinian A, Kägi D, Hakem A, McCurrach M, Khoo W, Kaufman SA, Senaldi G, Howard T, Lowe SW, Mak TW. Woo M, et al. Among authors: hakem a, hakem r. Genes Dev. 1998 Mar 15;12(6):806-19. doi: 10.1101/gad.12.6.806. Genes Dev. 1998. PMID: 9512515 Free PMC article.

4

Differential requirement for caspase 9 in apoptotic pathways in vivo.

Hakem R, Hakem A, Duncan GS, Henderson JT, Woo M, Soengas MS, Elia A, de la Pompa JL, Kagi D, Khoo W, Potter J, Yoshida R, Kaufman SA, Lowe SW, Penninger JM, Mak TW. Hakem R, et al. Among authors: hakem a. Cell. 1998 Aug 7;94(3):339-52. doi: 10.1016/s0092-8674(00)81477-4. Cell. 1998. PMID: 9708736 Free article.

5

Apaf1 is required for mitochondrial pathways of apoptosis and brain development.

Yoshida H, Kong YY, Yoshida R, Elia AJ, Hakem A, Hakem R, Penninger JM, Mak TW. Yoshida H, et al. Among authors: hakem a, hakem r. Cell. 1998 Sep 18;94(6):739-50. doi: 10.1016/s0092-8674(00)81733-x. Cell. 1998. PMID: 9753321 Free article.

6

Gene targeting in the analysis of mammalian apoptosis and TNF receptor superfamily signaling.

Yeh WC, Hakem R, Woo M, Mak TW. Yeh WC, et al. Among authors: hakem r. Immunol Rev. 1999 Jun;169:283-302. doi: 10.1111/j.1600-065x.1999.tb01323.x. Immunol Rev. 1999. PMID: 10450525 Review.

7

In vivo evidence that caspase-3 is required for Fas-mediated apoptosis of hepatocytes.

Woo M, Hakem A, Elia AJ, Hakem R, Duncan GS, Patterson BJ, Mak TW. Woo M, et al. Among authors: hakem a, hakem r. J Immunol. 1999 Nov 1;163(9):4909-16. J Immunol. 1999. PMID: 10528193

8

Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death.

Joza N, Susin SA, Daugas E, Stanford WL, Cho SK, Li CY, Sasaki T, Elia AJ, Cheng HY, Ravagnan L, Ferri KF, Zamzami N, Wakeham A, Hakem R, Yoshida H, Kong YY, Mak TW, Zúñiga-Pflücker JC, Kroemer G, Penninger JM. Joza N, et al. Among authors: hakem r. Nature. 2001 Mar 29;410(6828):549-54. doi: 10.1038/35069004. Nature. 2001. PMID: 11279485

9

Animal models of tumor-suppressor genes.

Hakem R, Mak TW. Hakem R, et al. Annu Rev Genet. 2001;35:209-41. doi: 10.1146/annurev.genet.35.102401.090432. Annu Rev Genet. 2001. PMID: 11700283 Review.

10

Cross-talk between Chk1 and Chk2 in double-mutant thymocytes.

Zaugg K, Su YW, Reilly PT, Moolani Y, Cheung CC, Hakem R, Hirao A, Liu Q, Elledge SJ, Mak TW. Zaugg K, et al. Among authors: hakem r. Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):3805-10. doi: 10.1073/pnas.0611584104. Epub 2007 Feb 26. Proc Natl Acad Sci U S A. 2007. PMID: 17360434 Free PMC article.

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