Moras D - Search Results

1

Functional and structural characterization of the insertion region in the ligand binding domain of the vitamin D nuclear receptor.

Rochel N, Tocchini-Valentini G, Egea PF, Juntunen K, Garnier JM, Vihko P, Moras D. Rochel N, et al. Among authors: moras d. Eur J Biochem. 2001 Feb;268(4):971-9. doi: 10.1046/j.1432-1327.2001.01953.x. Eur J Biochem. 2001. PMID: 11179963 Free article.

2

Structural adaptability in the ligand-binding pocket of the ecdysone hormone receptor.

Billas IM, Iwema T, Garnier JM, Mitschler A, Rochel N, Moras D. Billas IM, et al. Among authors: moras d. Nature. 2003 Nov 6;426(6962):91-6. doi: 10.1038/nature02112. Epub 2003 Nov 2. Nature. 2003. PMID: 14595375

3

Crystal structures of the vitamin D nuclear receptor liganded with the vitamin D side chain analogues calcipotriol and seocalcitol, receptor agonists of clinical importance. Insights into a structural basis for the switching of calcipotriol to a receptor antagonist by further side chain modification.

Tocchini-Valentini G, Rochel N, Wurtz JM, Moras D. Tocchini-Valentini G, et al. Among authors: moras d. J Med Chem. 2004 Apr 8;47(8):1956-61. doi: 10.1021/jm0310582. J Med Chem. 2004. PMID: 15055995

4

Structural investigation of the ligand binding domain of the zebrafish VDR in complexes with 1alpha,25(OH)2D3 and Gemini: purification, crystallization and preliminary X-ray diffraction analysis.

Ciesielski F, Rochel N, Mitschler A, Kouzmenko A, Moras D. Ciesielski F, et al. Among authors: moras d. J Steroid Biochem Mol Biol. 2004 May;89-90(1-5):55-9. doi: 10.1016/j.jsbmb.2004.03.109. J Steroid Biochem Mol Biol. 2004. PMID: 15225747

5

Ligand binding domain of vitamin D receptors.

Rochel N, Moras D. Rochel N, et al. Among authors: moras d. Curr Top Med Chem. 2006;6(12):1229-41. doi: 10.2174/156802606777864926. Curr Top Med Chem. 2006. PMID: 16848737 Review.

6

Adaptability of the Vitamin D nuclear receptor to the synthetic ligand Gemini: remodelling the LBP with one side chain rotation.

Ciesielski F, Rochel N, Moras D. Ciesielski F, et al. Among authors: moras d. J Steroid Biochem Mol Biol. 2007 Mar;103(3-5):235-42. doi: 10.1016/j.jsbmb.2006.12.003. Epub 2007 Jan 10. J Steroid Biochem Mol Biol. 2007. PMID: 17218092

7

Crystal structure of the vitamin D nuclear receptor ligand binding domain in complex with a locked side chain analog of calcitriol.

Rochel N, Hourai S, Pérez-García X, Rumbo A, Mourino A, Moras D. Rochel N, et al. Among authors: moras d. Arch Biochem Biophys. 2007 Apr 15;460(2):172-6. doi: 10.1016/j.abb.2007.01.031. Epub 2007 Feb 20. Arch Biochem Biophys. 2007. PMID: 17346665

8

Structural and functional insights into the ligand-binding domain of a nonduplicated retinoid X nuclear receptor from the invertebrate chordate amphioxus.

Tocchini-Valentini GD, Rochel N, Escriva H, Germain P, Peluso-Iltis C, Paris M, Sanglier-Cianferani S, Van Dorsselaer A, Moras D, Laudet V. Tocchini-Valentini GD, et al. Among authors: moras d. J Biol Chem. 2009 Jan 16;284(3):1938-48. doi: 10.1074/jbc.M805692200. Epub 2008 Nov 4. J Biol Chem. 2009. PMID: 18986992 Free article.

9

Crystal structure of hereditary vitamin D-resistant rickets--associated mutant H305Q of vitamin D nuclear receptor bound to its natural ligand.

Rochel N, Hourai S, Moras D. Rochel N, et al. Among authors: moras d. J Steroid Biochem Mol Biol. 2010 Jul;121(1-2):84-7. doi: 10.1016/j.jsbmb.2010.04.008. Epub 2010 Apr 18. J Steroid Biochem Mol Biol. 2010. PMID: 20403435

10

Crystal structure of a vitamin D3 analog, ZK203278, showing dissociated profile.

Rochel N, Moras D. Rochel N, et al. Among authors: moras d. Anticancer Res. 2012 Jan;32(1):335-9. Anticancer Res. 2012. PMID: 22213324

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