Stachulski AV - Search Results

1

Synthesis, antimalarial activity, biomimetic iron(II) chemistry, and in vivo metabolism of novel, potent C-10-phenoxy derivatives of dihydroartemisinin.

O'Neill PM, Miller A, Bishop LP, Hindley S, Maggs JL, Ward SA, Roberts SM, Scheinmann F, Stachulski AV, Posner GH, Park BK. O'Neill PM, et al. Among authors: stachulski av. J Med Chem. 2001 Jan 4;44(1):58-68. doi: 10.1021/jm000987f. J Med Chem. 2001. PMID: 11141088

2

Efficient preparations of the beta-glucuronides of dihydroartemisinin and structural confirmation of the human glucuronide metabolite.

O'Neill PM, Scheinmann F, Stachulski AV, Maggs JL, Park BK. O'Neill PM, et al. Among authors: stachulski av. J Med Chem. 2001 Apr 26;44(9):1467-70. doi: 10.1021/jm001061a. J Med Chem. 2001. PMID: 11311070

3

Structure-activity relationships of some opiate glycosides.

Stachulski AV, Scheinmann F, Ferguson JR, Law JL, Lumbard KW, Hopkins P, Patel N, Clarke S, Gloyne A, Joel SP. Stachulski AV, et al. Bioorg Med Chem Lett. 2003 Mar 24;13(6):1207-14. doi: 10.1016/s0960-894x(03)00056-8. Bioorg Med Chem Lett. 2003. PMID: 12643945

4

Preparation, X-ray structure and reactivity of a stable glycosyl iodide.

Bickley J, Cottrell JA, Ferguson JR, Field RA, Harding JR, Hughes DL, Kartha KP, Law JL, Scheinmann F, Stachulski AV. Bickley J, et al. Among authors: stachulski av. Chem Commun (Camb). 2003 Jun 7;(11):1266-7. doi: 10.1039/b302629a. Chem Commun (Camb). 2003. PMID: 12809223

5

Syntheses and characterization of the acyl glucuronide and hydroxy metabolites of diclofenac.

Kenny JR, Maggs JL, Meng X, Sinnott D, Clarke SE, Park BK, Stachulski AV. Kenny JR, et al. Among authors: stachulski av. J Med Chem. 2004 May 20;47(11):2816-25. doi: 10.1021/jm030891w. J Med Chem. 2004. PMID: 15139759

6

Identification of isoflavone derivatives as effective anticryptosporidial agents in vitro and in vivo.

Stachulski AV, Berry NG, Lilian Low AC, Moores SL, Row E, Warhurst DC, Adagu IS, Rossignol JF. Stachulski AV, et al. J Med Chem. 2006 Feb 23;49(4):1450-4. doi: 10.1021/jm050973f. J Med Chem. 2006. PMID: 16480281

7

Activation of T cells by carbamazepine and carbamazepine metabolites.

Wu Y, Sanderson JP, Farrell J, Drummond NS, Hanson A, Bowkett E, Berry N, Stachulski AV, Clarke SE, Pichler WJ, Pirmohamed M, Park BK, Naisbitt DJ. Wu Y, et al. Among authors: stachulski av. J Allergy Clin Immunol. 2006 Jul;118(1):233-41. doi: 10.1016/j.jaci.2006.03.005. Epub 2006 Apr 27. J Allergy Clin Immunol. 2006. PMID: 16815161

8

Synthesis of 1,2,4-trioxepanes via application of thiol-olefin co-oxygenation methodology.

Amewu R, Stachulski AV, Berry NG, Ward SA, Davies J, Labat G, Rossignol JF, O'Neill PM. Amewu R, et al. Among authors: stachulski av. Bioorg Med Chem Lett. 2006 Dec 1;16(23):6124-30. doi: 10.1016/j.bmcl.2006.08.098. Epub 2006 Sep 15. Bioorg Med Chem Lett. 2006. PMID: 16978862

9

Investigation of the immunogenicity of diclofenac and diclofenac metabolites.

Naisbitt DJ, Sanderson LS, Meng X, Stachulski AV, Clarke SE, Park BK. Naisbitt DJ, et al. Among authors: stachulski av. Toxicol Lett. 2007 Jan 10;168(1):45-50. doi: 10.1016/j.toxlet.2006.10.014. Epub 2006 Nov 10. Toxicol Lett. 2007. PMID: 17123753

10

Acyl glucuronides: biological activity, chemical reactivity, and chemical synthesis.

Stachulski AV, Harding JR, Lindon JC, Maggs JL, Park BK, Wilson ID. Stachulski AV, et al. J Med Chem. 2006 Nov 30;49(24):6931-45. doi: 10.1021/jm060599z. J Med Chem. 2006. PMID: 17125245 Review. No abstract available.

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