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Loss of calpain 3 proteolytic activity leads to muscular dystrophy and to apoptosis-associated IkappaBalpha/nuclear factor kappaB pathway perturbation in mice.
Richard I, Roudaut C, Marchand S, Baghdiguian S, Herasse M, Stockholm D, Ono Y, Suel L, Bourg N, Sorimachi H, Lefranc G, Fardeau M, Sébille A, Beckmann JS. Richard I, et al. Among authors: sorimachi h. J Cell Biol. 2000 Dec 25;151(7):1583-90. doi: 10.1083/jcb.151.7.1583. J Cell Biol. 2000. PMID: 11134085 Free PMC article.
Stable expression of calpain 3 from a muscle transgene in vivo: immature muscle in transgenic mice suggests a role for calpain 3 in muscle maturation.
Spencer MJ, Guyon JR, Sorimachi H, Potts A, Richard I, Herasse M, Chamberlain J, Dalkilic I, Kunkel LM, Beckmann JS. Spencer MJ, et al. Among authors: sorimachi h. Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8874-9. doi: 10.1073/pnas.132269299. Epub 2002 Jun 19. Proc Natl Acad Sci U S A. 2002. PMID: 12084932 Free PMC article.
Structure and physiology of calpain, an enigmatic protease.
Ono Y, Sorimachi H, Suzuki K. Ono Y, et al. Among authors: sorimachi h. Biochem Biophys Res Commun. 1998 Apr 17;245(2):289-94. doi: 10.1006/bbrc.1998.8085. Biochem Biophys Res Commun. 1998. PMID: 9571143
Myopathy phenotype of transgenic mice expressing active site-mutated inactive p94 skeletal muscle-specific calpain, the gene product responsible for limb girdle muscular dystrophy type 2A.
Tagawa K, Taya C, Hayashi Y, Nakagawa M, Ono Y, Fukuda R, Karasuyama H, Toyama-Sorimachi N, Katsui Y, Hata S, Ishiura S, Nonaka I, Seyama Y, Arahata K, Yonekawa H, Sorimachi H, Suzuki K. Tagawa K, et al. Among authors: sorimachi h. Hum Mol Genet. 2000 May 22;9(9):1393-402. doi: 10.1093/hmg/9.9.1393. Hum Mol Genet. 2000. PMID: 10814721
222 results