Gerhardt E - Search Results

1

Protection by synergistic effects of adenovirus-mediated X-chromosome-linked inhibitor of apoptosis and glial cell line-derived neurotrophic factor gene transfer in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.

Eberhardt O, Coelln RV, Kugler S, Lindenau J, Rathke-Hartlieb S, Gerhardt E, Haid S, Isenmann S, Gravel C, Srinivasan A, Bahr M, Weller M, Dichgans J, Schulz JB. Eberhardt O, et al. Among authors: gerhardt e. J Neurosci. 2000 Dec 15;20(24):9126-34. doi: 10.1523/JNEUROSCI.20-24-09126.2000. J Neurosci. 2000. PMID: 11124990 Free PMC article.

2

Inhibition of 26S proteasome activity by α-synuclein is mediated by the proteasomal chaperone Rpn14/PAAF1.

Galka D, Ali TT, Bast A, Niederleithinger M, Gerhardt E, Motosugi R, Sakata E, Knop M, Outeiro TF, Popova B, Braus GH. Galka D, et al. Among authors: gerhardt e. Aging Cell. 2024 May;23(5):e14128. doi: 10.1111/acel.14128. Epub 2024 Feb 28. Aging Cell. 2024. PMID: 38415292 Free PMC article.

3

α-Synuclein triggers cofilin pathology and dendritic spine impairment via a PrP^C-CCR5 dependent pathway.

Oliveira da Silva MI, Santejo M, Babcock IW, Magalhães A, Minamide LS, Won SJ, Castillo E, Gerhardt E, Fahlbusch C, Swanson RA, Outeiro TF, Taipa R, Ruff M, Bamburg JR, Liz MA. Oliveira da Silva MI, et al. Among authors: gerhardt e. Cell Death Dis. 2024 Apr 13;15(4):264. doi: 10.1038/s41419-024-06630-9. Cell Death Dis. 2024. PMID: 38615035 Free PMC article.

4

Non-SUMOylated alternative spliced isoforms of alpha-synuclein are more aggregation-prone and toxic.

Hassanzadeh K, Morrone C, Akhtari K, Gerhardt E, Zaccagnini L, Outeiro TF, Feligioni M. Hassanzadeh K, et al. Among authors: gerhardt e. Mech Ageing Dev. 2023 Jan;209:111759. doi: 10.1016/j.mad.2022.111759. Epub 2022 Dec 2. Mech Ageing Dev. 2023. PMID: 36464085

5

Neuron-specific expression of therapeutic proteins: evaluation of different cellular promoters in recombinant adenoviral vectors.

Kügler S, Meyn L, Holzmüller H, Gerhardt E, Isenmann S, Schulz JB, Bähr M. Kügler S, et al. Among authors: gerhardt e. Mol Cell Neurosci. 2001 Jan;17(1):78-96. doi: 10.1006/mcne.2000.0929. Mol Cell Neurosci. 2001. PMID: 11161471

6

Cascade of caspase activation in potassium-deprived cerebellar granule neurons: targets for treatment with peptide and protein inhibitors of apoptosis.

Gerhardt E, Kügler S, Leist M, Beier C, Berliocchi L, Volbracht C, Weller M, Bähr M, Nicotera P, Schulz JB. Gerhardt E, et al. Mol Cell Neurosci. 2001 Apr;17(4):717-31. doi: 10.1006/mcne.2001.0962. Mol Cell Neurosci. 2001. PMID: 11312607

7

Potential synergistic protection of retinal ganglion cells from axotomy-induced apoptosis by adenoviral administration of glial cell line-derived neurotrophic factor and X-chromosome-linked inhibitor of apoptosis.

Straten G, Schmeer C, Kretz A, Gerhardt E, Kügler S, Schulz JB, Gravel C, Bähr M, Isenmann S. Straten G, et al. Among authors: gerhardt e. Neurobiol Dis. 2002 Oct;11(1):123-33. doi: 10.1006/nbdi.2002.0543. Neurobiol Dis. 2002. PMID: 12460552

8

Identification and functional characterization of a novel R621C mutation in the synphilin-1 gene in Parkinson's disease.

Marx FP, Holzmann C, Strauss KM, Li L, Eberhardt O, Gerhardt E, Cookson MR, Hernandez D, Farrer MJ, Kachergus J, Engelender S, Ross CA, Berger K, Schöls L, Schulz JB, Riess O, Krüger R. Marx FP, et al. Among authors: gerhardt e. Hum Mol Genet. 2003 Jun 1;12(11):1223-31. doi: 10.1093/hmg/ddg134. Hum Mol Genet. 2003. PMID: 12761037

9

Intracellular acidification by inhibition of the Na+/H+-exchanger leads to caspase-independent death of cerebellar granule neurons resembling paraptosis.

Schneider D, Gerhardt E, Bock J, Müller MM, Wolburg H, Lang F, Schulz JB. Schneider D, et al. Among authors: gerhardt e. Cell Death Differ. 2004 Jul;11(7):760-70. doi: 10.1038/sj.cdd.4401377. Cell Death Differ. 2004. PMID: 15017383

10

Chemotherapy-induced cell death in primary cerebellar granule neurons but not in astrocytes: in vitro paradigm of differential neurotoxicity.

Wick A, Wick W, Hirrlinger J, Gerhardt E, Dringen R, Dichgans J, Weller M, Schulz JB. Wick A, et al. Among authors: gerhardt e. J Neurochem. 2004 Dec;91(5):1067-74. doi: 10.1111/j.1471-4159.2004.02774.x. J Neurochem. 2004. PMID: 15569250 Free article.

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