Toogood P - Search Results

1

Pyrido[2,3-d]pyrimidin-7-one inhibitors of cyclin-dependent kinases.

Barvian M, Boschelli DH, Cossrow J, Dobrusin E, Fattaey A, Fritsch A, Fry D, Harvey P, Keller P, Garrett M, La F, Leopold W, McNamara D, Quin M, Trumpp-Kallmeyer S, Toogood P, Wu Z, Zhang E. Barvian M, et al. Among authors: toogood p. J Med Chem. 2000 Nov 30;43(24):4606-16. doi: 10.1021/jm000271k. J Med Chem. 2000. PMID: 11101352

2

Pyrido[2,3-d]pyrimidin-7-ones as specific inhibitors of cyclin-dependent kinase 4.

VanderWel SN, Harvey PJ, McNamara DJ, Repine JT, Keller PR, Quin J 3rd, Booth RJ, Elliott WL, Dobrusin EM, Fry DW, Toogood PL. VanderWel SN, et al. J Med Chem. 2005 Apr 7;48(7):2371-87. doi: 10.1021/jm049355+. J Med Chem. 2005. PMID: 15801830

3

Discovery of a potent and selective inhibitor of cyclin-dependent kinase 4/6.

Toogood PL, Harvey PJ, Repine JT, Sheehan DJ, VanderWel SN, Zhou H, Keller PR, McNamara DJ, Sherry D, Zhu T, Brodfuehrer J, Choi C, Barvian MR, Fry DW. Toogood PL, et al. J Med Chem. 2005 Apr 7;48(7):2388-406. doi: 10.1021/jm049354h. J Med Chem. 2005. PMID: 15801831

4

2-Aminoquinazoline inhibitors of cyclin-dependent kinases.

Bathini Y, Singh I, Harvey PJ, Keller PR, Singh R, Micetich RG, Fry DW, Dobrusin EM, Toogood PL. Bathini Y, et al. Bioorg Med Chem Lett. 2005 Sep 1;15(17):3881-5. doi: 10.1016/j.bmcl.2005.05.131. Bioorg Med Chem Lett. 2005. PMID: 15993068

5

Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts.

Fry DW, Harvey PJ, Keller PR, Elliott WL, Meade M, Trachet E, Albassam M, Zheng X, Leopold WR, Pryer NK, Toogood PL. Fry DW, et al. Mol Cancer Ther. 2004 Nov;3(11):1427-38. Mol Cancer Ther. 2004. PMID: 15542782

6

Cyclin-dependent kinase inhibitors for treating cancer.

Toogood PL. Toogood PL. Med Res Rev. 2001 Nov;21(6):487-98. doi: 10.1002/med.1021. Med Res Rev. 2001. PMID: 11607930 Review.

7

Inhibition of protein synthesis by didemnins: cell potency and SAR.

Ahuja D, Geiger A, Ramanjulu JM, Vera MD, SirDeshpande B, Pfizenmayer A, Abazeed M, Krosky DJ, Beidler D, Joullié MM, Toogood PL. Ahuja D, et al. Among authors: toogood pl. J Med Chem. 2000 Nov 2;43(22):4212-8. doi: 10.1021/jm000168v. J Med Chem. 2000. PMID: 11063617

8

Inhibition of protein-protein association by small molecules: approaches and progress.

Toogood PL. Toogood PL. J Med Chem. 2002 Apr 11;45(8):1543-58. doi: 10.1021/jm010468s. J Med Chem. 2002. PMID: 11931608 Review. No abstract available.

9

Discovery and SAR of benzyl phenyl ethers as inhibitors of bacterial phenylalanyl-tRNA synthetase.

Montgomery JI, Toogood PL, Hutchings KM, Liu J, Narasimhan L, Braden T, Dermyer MR, Kulynych AD, Smith YD, Warmus JS, Taylor C. Montgomery JI, et al. Bioorg Med Chem Lett. 2009 Feb 1;19(3):665-9. doi: 10.1016/j.bmcl.2008.12.054. Epub 2008 Dec 24. Bioorg Med Chem Lett. 2009. PMID: 19121937

10

Progress toward the development of agents to modulate the cell cycle.

Toogood PL. Toogood PL. Curr Opin Chem Biol. 2002 Aug;6(4):472-8. doi: 10.1016/s1367-5931(02)00342-3. Curr Opin Chem Biol. 2002. PMID: 12133723 Review.

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