Ayton PM - Search Results

1

A carboxy-terminal domain of ELL is required and sufficient for immortalization of myeloid progenitors by MLL-ELL.

DiMartino JF, Miller T, Ayton PM, Landewe T, Hess JL, Cleary ML, Shilatifard A. DiMartino JF, et al. Among authors: ayton pm. Blood. 2000 Dec 1;96(12):3887-93. Blood. 2000. PMID: 11090074 Free article.

2

The AF10 leucine zipper is required for leukemic transformation of myeloid progenitors by MLL-AF10.

DiMartino JF, Ayton PM, Chen EH, Naftzger CC, Young BD, Cleary ML. DiMartino JF, et al. Among authors: ayton pm. Blood. 2002 May 15;99(10):3780-5. doi: 10.1182/blood.v99.10.3780. Blood. 2002. PMID: 11986236 Free article.

3

Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9.

Ayton PM, Cleary ML. Ayton PM, et al. Genes Dev. 2003 Sep 15;17(18):2298-307. doi: 10.1101/gad.1111603. Epub 2003 Sep 2. Genes Dev. 2003. PMID: 12952893 Free PMC article.

4

Binding to nonmethylated CpG DNA is essential for target recognition, transactivation, and myeloid transformation by an MLL oncoprotein.

Ayton PM, Chen EH, Cleary ML. Ayton PM, et al. Mol Cell Biol. 2004 Dec;24(23):10470-8. doi: 10.1128/MCB.24.23.10470-10478.2004. Mol Cell Biol. 2004. PMID: 15542854 Free PMC article.

5

Self-association mediated by the Ras association 1 domain of AF6 activates the oncogenic potential of MLL-AF6.

Liedtke M, Ayton PM, Somervaille TC, Smith KS, Cleary ML. Liedtke M, et al. Among authors: ayton pm. Blood. 2010 Jul 8;116(1):63-70. doi: 10.1182/blood-2009-09-243386. Epub 2010 Apr 15. Blood. 2010. PMID: 20395419 Free PMC article.

6

Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins.

Ayton PM, Cleary ML. Ayton PM, et al. Oncogene. 2001 Sep 10;20(40):5695-707. doi: 10.1038/sj.onc.1204639. Oncogene. 2001. PMID: 11607819 Review.

7

Leukemia proto-oncoprotein MLL is proteolytically processed into 2 fragments with opposite transcriptional properties.

Yokoyama A, Kitabayashi I, Ayton PM, Cleary ML, Ohki M. Yokoyama A, et al. Among authors: ayton pm. Blood. 2002 Nov 15;100(10):3710-8. doi: 10.1182/blood-2002-04-1015. Epub 2002 Jun 28. Blood. 2002. PMID: 12393701 Free article.

8

Dimerization contributes to oncogenic activation of MLL chimeras in acute leukemias.

So CW, Lin M, Ayton PM, Chen EH, Cleary ML. So CW, et al. Among authors: ayton pm. Cancer Cell. 2003 Aug;4(2):99-110. doi: 10.1016/s1535-6108(03)00188-0. Cancer Cell. 2003. PMID: 12957285 Free article.

9

Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors.

Cozzio A, Passegué E, Ayton PM, Karsunky H, Cleary ML, Weissman IL. Cozzio A, et al. Among authors: ayton pm. Genes Dev. 2003 Dec 15;17(24):3029-35. doi: 10.1101/gad.1143403. Genes Dev. 2003. PMID: 14701873 Free PMC article.

10

MOZ-TIF2-induced acute myeloid leukemia requires the MOZ nucleosome binding motif and TIF2-mediated recruitment of CBP.

Deguchi K, Ayton PM, Carapeti M, Kutok JL, Snyder CS, Williams IR, Cross NC, Glass CK, Cleary ML, Gilliland DG. Deguchi K, et al. Among authors: ayton pm. Cancer Cell. 2003 Mar;3(3):259-71. doi: 10.1016/s1535-6108(03)00051-5. Cancer Cell. 2003. PMID: 12676584 Free article.

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