Maggs JL - Search Results

1

Metabolism of lamotrigine to a reactive arene oxide intermediate.

Maggs JL, Naisbitt DJ, Tettey JN, Pirmohamed M, Park BK. Maggs JL, et al. Chem Res Toxicol. 2000 Nov;13(11):1075-81. doi: 10.1021/tx0000825. Chem Res Toxicol. 2000. PMID: 11087428

2

Bioactivation of clozapine by murine cardiac tissue in vivo and in vitro.

Williams DP, O'Donnell CJ, Maggs JL, Leeder JS, Uetrecht J, Pirmohamed M, Park BK. Williams DP, et al. Among authors: maggs jl. Chem Res Toxicol. 2003 Oct;16(10):1359-64. doi: 10.1021/tx034035z. Chem Res Toxicol. 2003. PMID: 14565776

3

Metabolic and chemical origins of cross-reactive immunological reactions to arylamine benzenesulfonamides: T-cell responses to hydroxylamine and nitroso derivatives.

Castrejon JL, Lavergne SN, El-Sheikh A, Farrell J, Maggs JL, Sabbani S, O'Neill PM, Park BK, Naisbitt DJ. Castrejon JL, et al. Among authors: maggs jl. Chem Res Toxicol. 2010 Jan;23(1):184-92. doi: 10.1021/tx900329b. Chem Res Toxicol. 2010. PMID: 19954178

4

Oxidative bioactivation of abacavir in subcellular fractions of human antigen presenting cells.

Bell CC, Santoyo Castelazo A, Yang EL, Maggs JL, Jenkins RE, Tugwood J, O'Neill PM, Naisbitt DJ, Park BK. Bell CC, et al. Among authors: maggs jl. Chem Res Toxicol. 2013 Jul 15;26(7):1064-72. doi: 10.1021/tx400041v. Epub 2013 Jun 12. Chem Res Toxicol. 2013. PMID: 23697900

5

Abacavir forms novel cross-linking abacavir protein adducts in patients.

Meng X, Lawrenson AS, Berry NG, Maggs JL, French NS, Back DJ, Khoo SH, Naisbitt DJ, Park BK. Meng X, et al. Among authors: maggs jl. Chem Res Toxicol. 2014 Apr 21;27(4):524-35. doi: 10.1021/tx400406p. Epub 2014 Feb 26. Chem Res Toxicol. 2014. PMID: 24571427

6

Auto-oxidation of Isoniazid Leads to Isonicotinic-Lysine Adducts on Human Serum Albumin.

Meng X, Maggs JL, Usui T, Whitaker P, French NS, Naisbitt DJ, Park BK. Meng X, et al. Among authors: maggs jl. Chem Res Toxicol. 2015 Jan 20;28(1):51-8. doi: 10.1021/tx500285k. Epub 2014 Dec 9. Chem Res Toxicol. 2015. PMID: 25489718

7

Mass Spectrometric Characterization of Circulating Covalent Protein Adducts Derived from Epoxide Metabolites of Carbamazepine in Patients.

Yip VLM, Meng X, Maggs JL, Jenkins RE, Marlot PT, Marson AG, Park BK, Pirmohamed M. Yip VLM, et al. Among authors: maggs jl. Chem Res Toxicol. 2017 Jul 17;30(7):1419-1435. doi: 10.1021/acs.chemrestox.7b00063. Epub 2017 Jun 12. Chem Res Toxicol. 2017. PMID: 28562019

8

The metabolic formation of reactive intermediates from clozapine, a drug associated with agranulocytosis in man.

Maggs JL, Williams D, Pirmohamed M, Park BK. Maggs JL, et al. J Pharmacol Exp Ther. 1995 Dec;275(3):1463-75. J Pharmacol Exp Ther. 1995. PMID: 8531117

9

Bioactivation of carbamazepine in the rat in vivo. Evidence for the formation of reactive arene oxide(s).

Madden S, Maggs JL, Park BK. Madden S, et al. Among authors: maggs jl. Drug Metab Dispos. 1996 Apr;24(4):469-79. Drug Metab Dispos. 1996. PMID: 8801063

10

Structural basis for the haemotoxicity of dapsone: the importance of the sulphonyl group.

Mahmud R, Tingle MD, Maggs JL, Cronin MT, Dearden JC, Park BK. Mahmud R, et al. Among authors: maggs jl. Toxicology. 1997 Feb 14;117(1):1-11. doi: 10.1016/s0300-483x(96)03548-2. Toxicology. 1997. PMID: 9020194

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