De Strooper B - Search Results

1

Processing of beta-secretase by furin and other members of the proprotein convertase family.

Creemers JW, Ines Dominguez D, Plets E, Serneels L, Taylor NA, Multhaup G, Craessaerts K, Annaert W, De Strooper B. Creemers JW, et al. Among authors: de strooper b. J Biol Chem. 2001 Feb 9;276(6):4211-7. doi: 10.1074/jbc.M006947200. Epub 2000 Nov 8. J Biol Chem. 2001. PMID: 11071887 Free article.

2

Molecular cloning of the mouse gene coding for alpha 2-macroglobulin and targeting of the gene in embryonic stem cells.

Umans L, Serneels L, Hilliker C, Stas L, Overbergh L, De Strooper B, Van Leuven F, Van den Berghe H. Umans L, et al. Among authors: de strooper b. Genomics. 1994 Aug;22(3):519-29. doi: 10.1006/geno.1994.1425. Genomics. 1994. PMID: 7528166

3

Structure of the gene (LRP1) coding for the human alpha 2-macroglobulin receptor lipoprotein receptor-related protein.

Van Leuven F, Stas L, Hilliker C, Lorent K, Umans L, Serneels L, Overbergh L, Torrekens S, Moechars D, De Strooper B, et al. Van Leuven F, et al. Among authors: de strooper b. Genomics. 1994 Nov 1;24(1):78-89. doi: 10.1006/geno.1994.1584. Genomics. 1994. PMID: 7534747

4

Production of intracellular amyloid-containing fragments in hippocampal neurons expressing human amyloid precursor protein and protection against amyloidogenesis by subtle amino acid substitutions in the rodent sequence.

De Strooper B, Simons M, Multhaup G, Van Leuven F, Beyreuther K, Dotti CG. De Strooper B, et al. EMBO J. 1995 Oct 16;14(20):4932-8. doi: 10.1002/j.1460-2075.1995.tb00176.x. EMBO J. 1995. PMID: 7588622 Free PMC article.

5

Cloning, characterization, and chromosomal localization to 4p16 of the human gene (LRPAP1) coding for the alpha 2-macroglobulin receptor-associated protein and structural comparison with the murine gene coding for the 44-kDa heparin-binding protein.

Van Leuven F, Hilliker C, Serneels L, Umans L, Overbergh L, De Strooper B, Fryns JP, Van den Berghe H. Van Leuven F, et al. Among authors: de strooper b. Genomics. 1995 Jan 20;25(2):492-500. doi: 10.1016/0888-7543(95)80050-v. Genomics. 1995. PMID: 7789983

6

Amyloid precursor protein is not processed by furin, PACE 4, PC1/3, PC2, PC4 and PC5/6 of the furin family of proprotein processing enzymes.

De Strooper B, Creemers JW, Moechars D, Huylebroeck D, Van De Ven WJ, Van Leuven F, Van den Berghe H. De Strooper B, et al. Biochim Biophys Acta. 1995 Jan 19;1246(2):185-8. doi: 10.1016/0167-4838(94)00194-l. Biochim Biophys Acta. 1995. PMID: 7819286

7

Basolateral secretion of amyloid precursor protein in Madin-Darby canine kidney cells is disturbed by alterations of intracellular pH and by introducing a mutation associated with familial Alzheimer's disease.

De Strooper B, Craessaerts K, Dewachter I, Moechars D, Greenberg B, Van Leuven F, Van den Berghe H. De Strooper B, et al. J Biol Chem. 1995 Feb 24;270(8):4058-65. doi: 10.1074/jbc.270.8.4058. J Biol Chem. 1995. PMID: 7876155 Free article.

8

Study of the synthesis and secretion of normal and artificial mutants of murine amyloid precursor protein (APP): cleavage of APP occurs in a late compartment of the default secretion pathway.

De Strooper B, Umans L, Van Leuven F, Van Den Berghe H. De Strooper B, et al. J Cell Biol. 1993 Apr;121(2):295-304. doi: 10.1083/jcb.121.2.295. J Cell Biol. 1993. PMID: 8468348 Free PMC article.

We have previously shown that APP-secretase activity is not inhibited by exogenously added proteinase inhibitors of different specificity (De Strooper, B., F. Van Leuven, and H. Van Den Berghe. 1992. FEBS (Fed. Eur. Biochem. ...

We have previously shown that APP-secretase activity is not inhibited by exogenously added proteinase inhibitors of different specificity ( …

9

Exchanging the extracellular domain of amyloid precursor protein for horseradish peroxidase does not interfere with alpha-secretase cleavage of the beta-amyloid region, but randomizes secretion in Madin-Darby canine kidney cells.

De Strooper B, Craessaerts K, Van Leuven F, Van Den Berghe H. De Strooper B, et al. J Biol Chem. 1995 Dec 22;270(51):30310-4. doi: 10.1074/jbc.270.51.30310. J Biol Chem. 1995. PMID: 8530453 Free article.

10

Amyloidogenic processing of the human amyloid precursor protein in primary cultures of rat hippocampal neurons.

Simons M, de Strooper B, Multhaup G, Tienari PJ, Dotti CG, Beyreuther K. Simons M, et al. Among authors: de strooper b. J Neurosci. 1996 Feb 1;16(3):899-908. doi: 10.1523/JNEUROSCI.16-03-00899.1996. J Neurosci. 1996. PMID: 8558258 Free PMC article.

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