Baillie TA - Search Results

1

Metabolites of caspofungin acetate, a potent antifungal agent, in human plasma and urine.

Balani SK, Xu X, Arison BH, Silva MV, Gries A, DeLuna FA, Cui D, Kari PH, Ly T, Hop CE, Singh R, Wallace MA, Dean DC, Lin JH, Pearson PG, Baillie TA. Balani SK, et al. Among authors: baillie ta. Drug Metab Dispos. 2000 Nov;28(11):1274-8. Drug Metab Dispos. 2000. PMID: 11038152

2

Biotransformation of methyl isocyanate in the rat. Evidence for glutathione conjugation as a major pathway of metabolism and implications for isocyanate-mediated toxicities.

Slatter JG, Rashed MS, Pearson PG, Han DH, Baillie TA. Slatter JG, et al. Among authors: baillie ta. Chem Res Toxicol. 1991 Mar-Apr;4(2):157-61. doi: 10.1021/tx00020a006. Chem Res Toxicol. 1991. PMID: 1782345

3

The use of mass spectrometry in the study of chemically-reactive drug metabolites. Application of MS/MS and LC/MS to the analysis of glutathione- and related S-linked conjugates of N-methylformamide.

Baillie TA, Pearson PG, Rashed MS, Howald WN. Baillie TA, et al. J Pharm Biomed Anal. 1989;7(12):1351-60. doi: 10.1016/0731-7085(89)80140-2. J Pharm Biomed Anal. 1989. PMID: 2490521

4

Application of liquid chromatography/thermospray mass spectrometry to studies on the formation of glutathione and cysteine conjugates from monomethylcarbamate metabolites of bambuterol.

Rashed MS, Pearson PG, Han DH, Baillie TA. Rashed MS, et al. Among authors: baillie ta. Rapid Commun Mass Spectrom. 1989 Oct;3(10):360-3. doi: 10.1002/rcm.1290031012. Rapid Commun Mass Spectrom. 1989. PMID: 2520219

5

Applications of tandem mass spectrometry to the characterization of derivatized glutathione conjugates. Studies with S-(N-methylcarbamoyl)glutathione, a metabolite of the antineoplastic agent N-methylformamide.

Pearson PG, Threadgill MD, Howald WN, Baillie TA. Pearson PG, et al. Among authors: baillie ta. Biomed Environ Mass Spectrom. 1988 Oct;16(1-12):51-6. doi: 10.1002/bms.1200160110. Biomed Environ Mass Spectrom. 1988. PMID: 3242707

6

Metabolism of N-methylformamide in mice: primary kinetic deuterium isotope effect and identification of S-(N-methylcarbamoyl)glutathione as a metabolite.

Threadgill MD, Axworthy DB, Baillie TA, Farmer PB, Farrow KC, Gescher A, Kestell P, Pearson PG, Shaw AJ. Threadgill MD, et al. Among authors: baillie ta. J Pharmacol Exp Ther. 1987 Jul;242(1):312-9. J Pharmacol Exp Ther. 1987. PMID: 3612534

7

Metabolic chiral inversion of stiripentol in the rat. I. Mechanistic studies.

Zhang K, Tang C, Rashed M, Cui D, Tombret F, Botte H, Lepage F, Levy RH, Baillie TA. Zhang K, et al. Among authors: baillie ta. Drug Metab Dispos. 1994 Jul-Aug;22(4):544-53. Drug Metab Dispos. 1994. PMID: 7956728

8

Studies on the metabolic fate of caracemide, an experimental antitumor agent, in the rat. Evidence for the release of methyl isocyanate in vivo.

Slatter JG, Davis MR, Han DH, Pearson PG, Baillie TA. Slatter JG, et al. Among authors: baillie ta. Chem Res Toxicol. 1993 May-Jun;6(3):335-40. doi: 10.1021/tx00033a013. Chem Res Toxicol. 1993. PMID: 8318655

9

In vitro studies on the metabolic activation of the furanopyridine L-754,394, a highly potent and selective mechanism-based inhibitor of cytochrome P450 3A4.

Sahali-Sahly Y, Balani SK, Lin JH, Baillie TA. Sahali-Sahly Y, et al. Among authors: baillie ta. Chem Res Toxicol. 1996 Sep;9(6):1007-12. doi: 10.1021/tx960060b. Chem Res Toxicol. 1996. PMID: 8870989

10

In vitro and in vivo evaluations of the metabolism, pharmacokinetics, and bioavailability of ester prodrugs of L-767,679, a potent fibrinogen receptor antagonist: an approach for the selection of a prodrug candidate.

Prueksaritanont T, Gorham LM, Breslin MJ, Hutchinson JH, Hartman GD, Vyas KP, Baillie TA. Prueksaritanont T, et al. Among authors: baillie ta. Drug Metab Dispos. 1997 Aug;25(8):978-84. Drug Metab Dispos. 1997. PMID: 9280406

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