Anton M - Search Results

1

Structural basis for lipoxygenase specificity. Conversion of the human leukocyte 5-lipoxygenase to a 15-lipoxygenating enzyme species by site-directed mutagenesis.

Schwarz K, Walther M, Anton M, Gerth C, Feussner I, Kuhn H. Schwarz K, et al. Among authors: anton m. J Biol Chem. 2001 Jan 5;276(1):773-9. doi: 10.1074/jbc.M005114200. J Biol Chem. 2001. PMID: 11027682 Free article.

2

The N-terminal domain of the reticulocyte-type 15-lipoxygenase is not essential for enzymatic activity but contains determinants for membrane binding.

Walther M, Anton M, Wiedmann M, Fletterick R, Kuhn H. Walther M, et al. Among authors: anton m. J Biol Chem. 2002 Jul 26;277(30):27360-6. doi: 10.1074/jbc.M203234200. Epub 2002 May 9. J Biol Chem. 2002. PMID: 12004065 Free article.

3

Amino acid differences in the deduced 5-lipoxygenase sequence of CAST atherosclerosis-resistance mice confer impaired activity when introduced into the human ortholog.

Kuhn H, Anton M, Gerth C, Habenicht A. Kuhn H, et al. Among authors: anton m. Arterioscler Thromb Vasc Biol. 2003 Jun 1;23(6):1072-6. doi: 10.1161/01.ATV.0000074167.01184.48. Epub 2003 May 1. Arterioscler Thromb Vasc Biol. 2003. PMID: 12730086

4

Molecular basis for the reduced catalytic activity of the naturally occurring T560M mutant of human 12/15-lipoxygenase that has been implicated in coronary artery disease.

Schurmann K, Anton M, Ivanov I, Richter C, Kuhn H, Walther M. Schurmann K, et al. Among authors: anton m. J Biol Chem. 2011 Jul 8;286(27):23920-7. doi: 10.1074/jbc.M110.211821. Epub 2011 May 10. J Biol Chem. 2011. PMID: 21558275 Free PMC article.

5

Stereocontrol of arachidonic acid oxygenation by vertebrate lipoxygenases: newly cloned zebrafish lipoxygenase 1 does not follow the Ala-versus-Gly concept.

Jansen C, Hofheinz K, Vogel R, Roffeis J, Anton M, Reddanna P, Kuhn H, Walther M. Jansen C, et al. Among authors: anton m. J Biol Chem. 2011 Oct 28;286(43):37804-12. doi: 10.1074/jbc.M111.259242. Epub 2011 Aug 31. J Biol Chem. 2011. PMID: 21880725 Free PMC article.

6

Probing the substrate alignment at the active site of 15-lipoxygenases by targeted substrate modification and site-directed mutagenesis. Evidence for an inverse substrate orientation.

Schwarz K, Borngräber S, Anton M, Kuhn H. Schwarz K, et al. Among authors: anton m. Biochemistry. 1998 Nov 3;37(44):15327-35. doi: 10.1021/bi9816204. Biochemistry. 1998. PMID: 9799493

7

Shape and specificity in mammalian 15-lipoxygenase active site. The functional interplay of sequence determinants for the reaction specificity.

Borngräber S, Browner M, Gillmor S, Gerth C, Anton M, Fletterick R, Kühn H. Borngräber S, et al. Among authors: anton m. J Biol Chem. 1999 Dec 24;274(52):37345-50. doi: 10.1074/jbc.274.52.37345. J Biol Chem. 1999. PMID: 10601303 Free article.

8

Alterations in leukotriene synthase activity of the human 5-lipoxygenase by site-directed mutagenesis affecting its positional specificity.

Schwarz K, Gerth C, Anton M, Kuhn H. Schwarz K, et al. Among authors: anton m. Biochemistry. 2000 Nov 28;39(47):14515-21. doi: 10.1021/bi001447n. Biochemistry. 2000. PMID: 11087405

9

Structural basis for pH-dependent alterations of reaction specificity of vertebrate lipoxygenase isoforms.

Walther M, Roffeis J, Jansen C, Anton M, Ivanov I, Kuhn H. Walther M, et al. Among authors: anton m. Biochim Biophys Acta. 2009 Aug;1791(8):827-35. doi: 10.1016/j.bbalip.2009.05.007. Epub 2009 May 28. Biochim Biophys Acta. 2009. PMID: 19481615

10

Sequence determinants for the positional specificity of lipoxygenases.

Schwarz K, Anton M, Kuhn H. Schwarz K, et al. Among authors: anton m. Adv Exp Med Biol. 2002;507:55-60. doi: 10.1007/978-1-4615-0193-0_9. Adv Exp Med Biol. 2002. PMID: 12664564 Review. No abstract available.

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