Alvarez RD - Search Results

1

Antineoplastic effect of anti-erbB-2 intrabody is not correlated with scFv affinity for its target.

Arafat W, Gómez-Navarro J, Xiang J, Siegal GP, Alvarez RD, Curiel DT. Arafat W, et al. Among authors: alvarez rd. Cancer Gene Ther. 2000 Sep;7(9):1250-6. doi: 10.1038/sj.cgt.7700228. Cancer Gene Ther. 2000. PMID: 11023197

2

Replication of an integrin targeted conditionally replicating adenovirus on primary ovarian cancer spheroids.

Lam JT, Bauerschmitz GJ, Kanerva A, Barker SD, Straughn JM, Wang M, Barnes MN, Blackwell JL, Siegal GP, Alvarez RD, Curiel DT, Hemminki A. Lam JT, et al. Among authors: alvarez rd. Cancer Gene Ther. 2003 May;10(5):377-87. doi: 10.1038/sj.cgt.7700578. Cancer Gene Ther. 2003. PMID: 12719707

3

Targeted tumor killing via an intracellular antibody against erbB-2.

Deshane J, Siegal GP, Alvarez RD, Wang MH, Feng M, Cabrera G, Liu T, Kay M, Curiel DT. Deshane J, et al. Among authors: alvarez rd. J Clin Invest. 1995 Dec;96(6):2980-9. doi: 10.1172/JCI118370. J Clin Invest. 1995. PMID: 8675670 Free PMC article.

4

Intracellular antibody against erbB-2 mediates targeted tumor cell eradication by apoptosis.

Deshane J, Grim J, Loechel S, Siegal GP, Alvarez RD, Curiel DT. Deshane J, et al. Among authors: alvarez rd. Cancer Gene Ther. 1996 Mar-Apr;3(2):89-98. Cancer Gene Ther. 1996. PMID: 8729907

5

A phase I study of recombinant adenovirus vector-mediated delivery of an anti-erbB-2 single-chain (sFv) antibody gene for previously treated ovarian and extraovarian cancer patients.

Alvarez RD, Curiel DT. Alvarez RD, et al. Hum Gene Ther. 1997 Jan 20;8(2):229-42. doi: 10.1089/hum.1997.8.2-229. Hum Gene Ther. 1997. PMID: 9017426 No abstract available.

6

Transductional efficacy and safety of an intraperitoneally delivered adenovirus encoding an anti-erbB-2 intracellular single-chain antibody for ovarian cancer gene therapy.

Deshane J, Siegal GP, Wang M, Wright M, Bucy RP, Alvarez RD, Curiel DT. Deshane J, et al. Among authors: alvarez rd. Gynecol Oncol. 1997 Mar;64(3):378-85. doi: 10.1006/gyno.1996.4566. Gynecol Oncol. 1997. PMID: 9062138

7

Intracellular expression of a single-chain antibody directed against human papillomavirus type 16 E7 oncoprotein achieves targeted antineoplastic effects.

Wang-Johanning F, Gillespie GY, Grim J, Rancourt C, Alvarez RD, Siegal GP, Curiel DT. Wang-Johanning F, et al. Among authors: alvarez rd. Cancer Res. 1998 May 1;58(9):1893-900. Cancer Res. 1998. PMID: 9581830

8

The level of erbB2 expression predicts sensitivity to the cytotoxic effects of an intracellular anti-erbB2 sFv.

Grim J, Deshane J, Siegal GP, Alvarez RD, DiFiore P, Curiel DT. Grim J, et al. Among authors: alvarez rd. J Mol Med (Berl). 1998 May;76(6):451-8. doi: 10.1007/s001090050237. J Mol Med (Berl). 1998. PMID: 9625302

9

Intracellular expression of the anti-erbB-2 sFv N29 fails to accomplish efficient target modulation.

Grim JE, Siegal GP, Alvarez RD, Curiel DT. Grim JE, et al. Among authors: alvarez rd. Biochem Biophys Res Commun. 1998 Sep 29;250(3):699-703. doi: 10.1006/bbrc.1998.9391. Biochem Biophys Res Commun. 1998. PMID: 9784409

10

Novel gene therapy strategy to accomplish growth factor modulation induces enhanced tumor cell chemosensitivity.

Barnes MN, Deshane JS, Siegal GP, Alvarez RD, Curiel DT. Barnes MN, et al. Among authors: alvarez rd. Clin Cancer Res. 1996 Jul;2(7):1089-95. Clin Cancer Res. 1996. PMID: 9816272

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