Hamill T - Search Results

1

HIV-1 integrase inhibitors that compete with the target DNA substrate define a unique strand transfer conformation for integrase.

Espeseth AS, Felock P, Wolfe A, Witmer M, Grobler J, Anthony N, Egbertson M, Melamed JY, Young S, Hamill T, Cole JL, Hazuda DJ. Espeseth AS, et al. Among authors: hamill t. Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11244-9. doi: 10.1073/pnas.200139397. Proc Natl Acad Sci U S A. 2000. PMID: 11016953 Free PMC article.

2

Identification of low molecular weight GP IIb/IIIa antagonists that bind preferentially to activated platelets.

Bednar RA, Gaul SL, Hamill TG, Egbertson MS, Shafer JA, Hartman GD, Gould RJ, Bednar B. Bednar RA, et al. Among authors: hamill tg. J Pharmacol Exp Ther. 1998 Jun;285(3):1317-26. J Pharmacol Exp Ther. 1998. PMID: 9618439

3

[18F]MK-9470, a positron emission tomography (PET) tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor.

Burns HD, Van Laere K, Sanabria-Bohórquez S, Hamill TG, Bormans G, Eng WS, Gibson R, Ryan C, Connolly B, Patel S, Krause S, Vanko A, Van Hecken A, Dupont P, De Lepeleire I, Rothenberg P, Stoch SA, Cote J, Hagmann WK, Jewell JP, Lin LS, Liu P, Goulet MT, Gottesdiener K, Wagner JA, de Hoon J, Mortelmans L, Fong TM, Hargreaves RJ. Burns HD, et al. Among authors: hamill tg. Proc Natl Acad Sci U S A. 2007 Jun 5;104(23):9800-5. doi: 10.1073/pnas.0703472104. Epub 2007 May 29. Proc Natl Acad Sci U S A. 2007. PMID: 17535893 Free PMC article.

4

In vitro characterization of [3H]MethoxyPyEP, an mGluR5 selective radioligand.

Patel S, Krause SM, Hamill T, Chaudhary A, Burns DH, Gibson RA. Patel S, et al. Among authors: hamill t. Life Sci. 2003 Jun 6;73(3):371-9. doi: 10.1016/s0024-3205(03)00272-8. Life Sci. 2003. PMID: 12757844

5

Nonpeptide alpha(v)beta(3) antagonists. 1. Transformation of a potent, integrin-selective alpha(IIb)beta(3) antagonist into a potent alpha(v)beta(3) antagonist.

Duggan ME, Duong LT, Fisher JE, Hamill TG, Hoffman WF, Huff JR, Ihle NC, Leu CT, Nagy RM, Perkins JJ, Rodan SB, Wesolowski G, Whitman DB, Zartman AE, Rodan GA, Hartman GD. Duggan ME, et al. Among authors: hamill tg. J Med Chem. 2000 Oct 5;43(20):3736-45. doi: 10.1021/jm000133v. J Med Chem. 2000. PMID: 11020288

6

Disposition of L-738,167, a potent and long-acting fibrinogen receptor antagonist, in dogs. Dose-dependent pharmacokinetics.

Prueksaritanont T, Gorham LM, Naue JA, Hamill TG, Askew BC, Vyas KP. Prueksaritanont T, et al. Among authors: hamill tg. Drug Metab Dispos. 1997 Mar;25(3):355-61. Drug Metab Dispos. 1997. PMID: 9172954

7

Non-peptide glycoprotein IIb/IIIa inhibitors. 17. Design and synthesis of orally active, long-acting non-peptide fibrinogen receptor antagonists.

Askew BC, Bednar RA, Bednar B, Claremon DA, Cook JJ, McIntyre CJ, Hunt CA, Gould RJ, Lynch RJ, Lynch JJ Jr, Gaul SL, Stranieri MT, Sitko GR, Holahan MA, Glass JD, Hamill T, Gorham LM, Prueksaritanont T, Baldwin JJ, Hartman GD. Askew BC, et al. Among authors: hamill t. J Med Chem. 1997 Jun 6;40(12):1779-88. doi: 10.1021/jm9608117. J Med Chem. 1997. PMID: 9191954

8

Non-invasive radiotracer imaging as a tool for drug development.

Gibson RE, Burns HD, Hamill TG, Eng WS, Francis BE, Ryan C. Gibson RE, et al. Among authors: hamill tg. Curr Pharm Des. 2000 Jul;6(10):973-89. doi: 10.2174/1381612003399987. Curr Pharm Des. 2000. PMID: 10828297 Review.

9

Screening cascade and development of potential Positron Emission Tomography radiotracers for mGluR5: in vitro and in vivo characterization.

Patel S, Ndubizu O, Hamill T, Chaudhary A, Burns HD, Hargreaves R, Gibson RE. Patel S, et al. Among authors: hamill t. Mol Imaging Biol. 2005 Jul-Aug;7(4):314-23. doi: 10.1007/s11307-005-0005-4. Mol Imaging Biol. 2005. PMID: 16080024

10

An in vitro assay for predicting successful imaging radiotracers.

Patel S, Hamill T, Hostetler E, Burns HD, Gibson RE. Patel S, et al. Among authors: hamill t. Mol Imaging Biol. 2003 Mar-Apr;5(2):65-71. doi: 10.1016/s1536-1632(03)00041-6. Mol Imaging Biol. 2003. PMID: 14499146

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