Harling JD - Search Results

1

Evaluation of a series of anticonvulsant 1,2,3,4-tetrahydroisoquinolinyl-benzamides.

Chan WN, Hadley MS, Harling JD, Herdon HJ, Orlek BS, Riley GJ, Stead RE, Stean TO, Thompson M, Upton N, Ward RW. Chan WN, et al. Among authors: harling jd. Bioorg Med Chem. 2000 Aug;8(8):2085-94. doi: 10.1016/s0968-0896(00)00149-8. Bioorg Med Chem. 2000. PMID: 11003154

2

UV-DIB: label-free permeability determination using droplet interface bilayers.

Strutt R, Sheffield F, Barlow NE, Flemming AJ, Harling JD, Law RV, Brooks NJ, Barter LMC, Ces O. Strutt R, et al. Among authors: harling jd. Lab Chip. 2022 Mar 1;22(5):972-985. doi: 10.1039/d1lc01155c. Lab Chip. 2022. PMID: 35107110

3

A two-faced selectivity solution to target SMARCA2 for cancer therapy.

Harling JD, Tinworth CP. Harling JD, et al. Nat Commun. 2023 Jan 31;14(1):515. doi: 10.1038/s41467-023-36238-0. Nat Commun. 2023. PMID: 36720862 Free PMC article.

4

Activating mechanosensitive channels embedded in droplet interface bilayers using membrane asymmetry.

Strutt R, Hindley JW, Gregg J, Booth PJ, Harling JD, Law RV, Friddin MS, Ces O. Strutt R, et al. Among authors: harling jd. Chem Sci. 2021 Jan 4;12(6):2138-2145. doi: 10.1039/d0sc03889j. Chem Sci. 2021. PMID: 34163978 Free PMC article.

5

Identification of a series of 1,2,3,4-tetrahydroisoquinolinyl-benzamides with potential anticonvulsant activity.

Chan WN, Hadley MS, Harling JD, Herdon HJ, Jerman JC, Orlek BS, Stean TO, Thompson M, Upton N, Ward RW. Chan WN, et al. Among authors: harling jd. Bioorg Med Chem Lett. 1998 Oct 20;8(20):2903-6. doi: 10.1016/s0960-894x(98)00523-x. Bioorg Med Chem Lett. 1998. PMID: 9873645

6

Characterisation of SB-221420-A - a neuronal Ca(2+) and Na(+) channel antagonist in experimental models of stroke.

Campbell CA, Barone FC, Benham CD, Hadingham SJ, Harries MH, Harling JD, Hills JM, Lewis VA, Mackay KB, Orlek BS, White RF, Parsons AA, Hunter AJ. Campbell CA, et al. Among authors: harling jd. Eur J Pharmacol. 2000 Aug 11;401(3):419-28. doi: 10.1016/s0014-2999(00)00470-2. Eur J Pharmacol. 2000. PMID: 10936502

7

The design of 8,8-dimethyl[1,6]naphthyridines as potential anticonvulsant agents.

Austin NE, Hadley MS, Harling JD, Harrington FP, Macdonald GJ, Mitchell DJ, Riley GJ, Stean TO, Stemp G, Stratton SC, Thompson M, Upton N. Austin NE, et al. Among authors: harling jd. Bioorg Med Chem Lett. 2003 May 19;13(10):1627-9. doi: 10.1016/s0960-894x(03)00288-9. Bioorg Med Chem Lett. 2003. PMID: 12729628

8

(1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: a novel class of potent MSK-1-inhibitors.

Bamford MJ, Alberti MJ, Bailey N, Davies S, Dean DK, Gaiba A, Garland S, Harling JD, Jung DK, Panchal TA, Parr CA, Steadman JG, Takle AK, Townsend JT, Wilson DM, Witherington J. Bamford MJ, et al. Among authors: harling jd. Bioorg Med Chem Lett. 2005 Jul 15;15(14):3402-6. doi: 10.1016/j.bmcl.2005.05.021. Bioorg Med Chem Lett. 2005. PMID: 15950465

9

Identification of novel inhibitors of the transforming growth factor beta1 (TGF-beta1) type 1 receptor (ALK5).

Callahan JF, Burgess JL, Fornwald JA, Gaster LM, Harling JD, Harrington FP, Heer J, Kwon C, Lehr R, Mathur A, Olson BA, Weinstock J, Laping NJ. Callahan JF, et al. Among authors: harling jd. J Med Chem. 2002 Feb 28;45(5):999-1001. doi: 10.1021/jm010493y. J Med Chem. 2002. PMID: 11855979

10

Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with monoaryl P4 motifs.

Kleanthous S, Borthwick AD, Brown D, Burns-Kurtis CL, Campbell M, Chaudry L, Chan C, Clarte MO, Convery MA, Harling JD, Hortense E, Irving WR, Irvine S, Pateman AJ, Patikis AN, Pinto IL, Pollard DR, Roethka TJ, Senger S, Shah GP, Stelman GJ, Toomey JR, Watson NS, West RI, Whittaker C, Zhou P, Young RJ. Kleanthous S, et al. Among authors: harling jd. Bioorg Med Chem Lett. 2010 Jan 15;20(2):618-22. doi: 10.1016/j.bmcl.2009.11.077. Epub 2009 Nov 20. Bioorg Med Chem Lett. 2010. PMID: 20006499

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