Waksman G - Search Results

1

Role of electrostatic interactions in SH2 domain recognition: salt-dependence of tyrosyl-phosphorylated peptide binding to the tandem SH2 domain of the Syk kinase and the single SH2 domain of the Src kinase.

Grucza RA, Bradshaw JM, Mitaxov V, Waksman G. Grucza RA, et al. Among authors: waksman g. Biochemistry. 2000 Aug 22;39(33):10072-81. doi: 10.1021/bi000891n. Biochemistry. 2000. PMID: 10955995

2

Molecular recognition by SH2 domains.

Bradshaw JM, Waksman G. Bradshaw JM, et al. Among authors: waksman g. Adv Protein Chem. 2002;61:161-210. doi: 10.1016/s0065-3233(02)61005-8. Adv Protein Chem. 2002. PMID: 12461824 Review.

3

The tandem Src homology 2 domain of the Syk kinase: a molecular device that adapts to interphosphotyrosine distances.

Kumaran S, Grucza RA, Waksman G. Kumaran S, et al. Among authors: waksman g. Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):14828-33. doi: 10.1073/pnas.2432867100. Epub 2003 Dec 1. Proc Natl Acad Sci U S A. 2003. PMID: 14657388 Free PMC article.

4

Structural basis for Syk tyrosine kinase ubiquity in signal transduction pathways revealed by the crystal structure of its regulatory SH2 domains bound to a dually phosphorylated ITAM peptide.

Fütterer K, Wong J, Grucza RA, Chan AC, Waksman G. Fütterer K, et al. Among authors: waksman g. J Mol Biol. 1998 Aug 21;281(3):523-37. doi: 10.1006/jmbi.1998.1964. J Mol Biol. 1998. PMID: 9698567

5

Thermodynamic study of the binding of the tandem-SH2 domain of the Syk kinase to a dually phosphorylated ITAM peptide: evidence for two conformers.

Grucza RA, Fütterer K, Chan AC, Waksman G. Grucza RA, et al. Among authors: waksman g. Biochemistry. 1999 Apr 20;38(16):5024-33. doi: 10.1021/bi9829938. Biochemistry. 1999. PMID: 10213605

6

Calorimetric examination of high-affinity Src SH2 domain-tyrosyl phosphopeptide binding: dissection of the phosphopeptide sequence specificity and coupling energetics.

Bradshaw JM, Waksman G. Bradshaw JM, et al. Among authors: waksman g. Biochemistry. 1999 Apr 20;38(16):5147-54. doi: 10.1021/bi982974y. Biochemistry. 1999. PMID: 10213620

7

SH2 domains: from structure to energetics, a dual approach to the study of structure-function relationships.

Grucza RA, Bradshaw JM, Fütterer K, Waksman G. Grucza RA, et al. Among authors: waksman g. Med Res Rev. 1999 Jul;19(4):273-93. doi: 10.1002/(sici)1098-1128(199907)19:4<273::aid-med2>3.0.co;2-g. Med Res Rev. 1999. PMID: 10398925 Review. No abstract available.

8

Investigation of phosphotyrosine recognition by the SH2 domain of the Src kinase.

Bradshaw JM, Mitaxov V, Waksman G. Bradshaw JM, et al. Among authors: waksman g. J Mol Biol. 1999 Nov 5;293(4):971-85. doi: 10.1006/jmbi.1999.3190. J Mol Biol. 1999. PMID: 10543978

9

Mutational investigation of the specificity determining region of the Src SH2 domain.

Bradshaw JM, Mitaxov V, Waksman G. Bradshaw JM, et al. Among authors: waksman g. J Mol Biol. 2000 Jun 2;299(2):521-35. doi: 10.1006/jmbi.2000.3765. J Mol Biol. 2000. PMID: 10860756

10

pH-Dependent self-association of the Src homology 2 (SH2) domain of the Src homologous and collagen-like (SHC) protein.

Réty S, Fütterer K, Grucza RA, Munoz CM, Frazier WA, Waksman G. Réty S, et al. Among authors: waksman g. Protein Sci. 1996 Mar;5(3):405-13. doi: 10.1002/pro.5560050301. Protein Sci. 1996. PMID: 8868476 Free PMC article.

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