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Mice overexpressing human uncoupling protein-3 in skeletal muscle are hyperphagic and lean.
Clapham JC, Arch JR, Chapman H, Haynes A, Lister C, Moore GB, Piercy V, Carter SA, Lehner I, Smith SA, Beeley LJ, Godden RJ, Herrity N, Skehel M, Changani KK, Hockings PD, Reid DG, Squires SM, Hatcher J, Trail B, Latcham J, Rastan S, Harper AJ, Cadenas S, Buckingham JA, Brand MD, Abuin A. Clapham JC, et al. Among authors: cadenas s. Nature. 2000 Jul 27;406(6794):415-8. doi: 10.1038/35019082. Nature. 2000. PMID: 10935638
Superoxide activates mitochondrial uncoupling proteins.
Echtay KS, Roussel D, St-Pierre J, Jekabsons MB, Cadenas S, Stuart JA, Harper JA, Roebuck SJ, Morrison A, Pickering S, Clapham JC, Brand MD. Echtay KS, et al. Among authors: cadenas s. Nature. 2002 Jan 3;415(6867):96-9. doi: 10.1038/415096a. Nature. 2002. PMID: 11780125
Mitochondrial proton leak and the uncoupling protein 1 homologues.
Stuart JA, Cadenas S, Jekabsons MB, Roussel D, Brand MD. Stuart JA, et al. Among authors: cadenas s. Biochim Biophys Acta. 2001 Mar 1;1504(1):144-58. doi: 10.1016/s0005-2728(00)00243-7. Biochim Biophys Acta. 2001. PMID: 11239491 Free article. Review.
Rapamycin negatively impacts insulin signaling, glucose uptake and uncoupling protein-1 in brown adipocytes.
García-Casarrubios E, de Moura C, Arroba AI, Pescador N, Calderon-Dominguez M, Garcia L, Herrero L, Serra D, Cadenas S, Reis F, Carvalho E, Obregon MJ, Valverde ÁM. García-Casarrubios E, et al. Among authors: cadenas s. Biochim Biophys Acta. 2016 Dec;1861(12 Pt A):1929-1941. doi: 10.1016/j.bbalip.2016.09.016. Epub 2016 Sep 26. Biochim Biophys Acta. 2016. PMID: 27686967
76 results