Edes K - Search Results

1

Inactivation of wild-type p53 tumor suppressor by electrophilic prostaglandins.

Moos PJ, Edes K, Fitzpatrick FA. Moos PJ, et al. Among authors: edes k. Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):9215-20. doi: 10.1073/pnas.160241897. Proc Natl Acad Sci U S A. 2000. PMID: 10908664 Free PMC article.

2

Electrophilic prostaglandins and lipid aldehydes repress redox-sensitive transcription factors p53 and hypoxia-inducible factor by impairing the selenoprotein thioredoxin reductase.

Moos PJ, Edes K, Cassidy P, Massuda E, Fitzpatrick FA. Moos PJ, et al. Among authors: edes k. J Biol Chem. 2003 Jan 10;278(2):745-50. doi: 10.1074/jbc.M211134200. Epub 2002 Nov 6. J Biol Chem. 2003. PMID: 12424231 Free article.

3

Curcumin impairs tumor suppressor p53 function in colon cancer cells.

Moos PJ, Edes K, Mullally JE, Fitzpatrick FA. Moos PJ, et al. Among authors: edes k. Carcinogenesis. 2004 Sep;25(9):1611-7. doi: 10.1093/carcin/bgh163. Epub 2004 Apr 16. Carcinogenesis. 2004. PMID: 15090465

4

Thioredoxin reductase is required for the inactivation of tumor suppressor p53 and for apoptosis induced by endogenous electrophiles.

Cassidy PB, Edes K, Nelson CC, Parsawar K, Fitzpatrick FA, Moos PJ. Cassidy PB, et al. Among authors: edes k. Carcinogenesis. 2006 Dec;27(12):2538-49. doi: 10.1093/carcin/bgl111. Epub 2006 Jun 15. Carcinogenesis. 2006. PMID: 16777982

5

Cyclopentenone prostaglandins of the J series inhibit the ubiquitin isopeptidase activity of the proteasome pathway.

Mullally JE, Moos PJ, Edes K, Fitzpatrick FA. Mullally JE, et al. Among authors: edes k. J Biol Chem. 2001 Aug 10;276(32):30366-73. doi: 10.1074/jbc.M102198200. Epub 2001 Jun 4. J Biol Chem. 2001. PMID: 11390388 Free article.

6

Oxidation of 2-Cys-peroxiredoxins by arachidonic acid peroxide metabolites of lipoxygenases and cyclooxygenase-2.

Cordray P, Doyle K, Edes K, Moos PJ, Fitzpatrick FA. Cordray P, et al. Among authors: edes k. J Biol Chem. 2007 Nov 9;282(45):32623-9. doi: 10.1074/jbc.M704369200. Epub 2007 Sep 13. J Biol Chem. 2007. PMID: 17855346 Free article.

7

JS-K, a nitric oxide prodrug, has enhanced cytotoxicity in colon cancer cells with knockdown of thioredoxin reductase 1.

Edes K, Cassidy P, Shami PJ, Moos PJ. Edes K, et al. PLoS One. 2010 Jan 20;5(1):e8786. doi: 10.1371/journal.pone.0008786. PLoS One. 2010. PMID: 20098717 Free PMC article.

8

Akt activation by arachidonic acid metabolism occurs via oxidation and inactivation of PTEN tumor suppressor.

Covey TM, Edes K, Fitzpatrick FA. Covey TM, et al. Among authors: edes k. Oncogene. 2007 Aug 23;26(39):5784-92. doi: 10.1038/sj.onc.1210391. Epub 2007 Mar 19. Oncogene. 2007. PMID: 17369849

9

Alkylation of the tumor suppressor PTEN activates Akt and β-catenin signaling: a mechanism linking inflammation and oxidative stress with cancer.

Covey TM, Edes K, Coombs GS, Virshup DM, Fitzpatrick FA. Covey TM, et al. Among authors: edes k. PLoS One. 2010 Oct 21;5(10):e13545. doi: 10.1371/journal.pone.0013545. PLoS One. 2010. PMID: 20975834 Free PMC article.

10

Juxtaposition of chemical and mutation-induced developmental defects in zebrafish reveal a copper-chelating activity for kalihinol F.

Sandoval IT, Manos EJ, Van Wagoner RM, Delacruz RG, Edes K, Winge DR, Ireland CM, Jones DA. Sandoval IT, et al. Among authors: edes k. Chem Biol. 2013 Jun 20;20(6):753-63. doi: 10.1016/j.chembiol.2013.05.008. Chem Biol. 2013. PMID: 23790486 Free PMC article.

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