Torrence PF - Search Results

1

Convergent synthesis of ribonuclease L-active 2',5'-oligoadenylate-peptide nucleic acids.

Wang Z, Chen L, Bayly SF, Torrence PF. Wang Z, et al. Among authors: torrence pf. Bioorg Med Chem Lett. 2000 Jun 19;10(12):1357-60. doi: 10.1016/s0960-894x(00)00240-7. Bioorg Med Chem Lett. 2000. PMID: 10890163

2

Probing the activation site of ribonuclease L with new N6-substituted 2',5'-adenylate trimers.

Münch U, Chen L, Bayly SF, Torrence PF. Münch U, et al. Among authors: torrence pf. Bioorg Med Chem. 2003 May 1;11(9):2041-9. doi: 10.1016/s0968-0896(03)00060-9. Bioorg Med Chem. 2003. PMID: 12670655

3

2,5-oligoadenylate-peptide nucleic acids (2-5A-PNAs) activate RNase L.

Verheijen JC, van der Marel GA, van Boom JH, Bayly SF, Player MR, Torrence PF. Verheijen JC, et al. Among authors: torrence pf. Bioorg Med Chem. 1999 Mar;7(3):449-55. doi: 10.1016/s0968-0896(98)00258-2. Bioorg Med Chem. 1999. PMID: 10220031

4

2-Methyladenosine-Substituted 2',5'-oligoadenylates: conformations, 2-5A binding and catalytic activities with human ribonuclease L.

Kitade Y, Wakana M, Tsuboi T, Yatome C, Bayly SF, Player MR, Torrence PF. Kitade Y, et al. Among authors: torrence pf. Bioorg Med Chem Lett. 2000 Feb 21;10(4):329-31. doi: 10.1016/s0960-894x(99)00703-9. Bioorg Med Chem Lett. 2000. PMID: 10714492

5

Incorporation of a 4-hydroxy-N-acetylprolinol nucleotide analogue improves the 3'-exonuclease stability of 2'-5'-oligoadenylate-antisense conjugates.

Verheijen JC, van Roon AM, Meeuwenoord NJ, Stuivenberg HR, Bayly SF, Chen L, van der Marel GA, Torrence PF, van Boom JH. Verheijen JC, et al. Among authors: torrence pf. Bioorg Med Chem Lett. 2000 Apr 17;10(8):801-4. doi: 10.1016/s0960-894x(00)00100-1. Bioorg Med Chem Lett. 2000. PMID: 10782690

6

Chemistry and biochemistry of 2',5'-oligoadenylate-based antisense strategy.

Adah SA, Bayly SF, Cramer H, Silverman RH, Torrence PF. Adah SA, et al. Among authors: torrence pf. Curr Med Chem. 2001 Aug;8(10):1189-212. doi: 10.2174/0929867013372445. Curr Med Chem. 2001. PMID: 11472236

7

Ribonuclease L, a 2-5A-dependent enzyme: purification to homogeneity and assays for 2-5A binding and catalytic activity.

Player MR, Wondrak EM, Bayly SF, Torrence PF. Player MR, et al. Among authors: torrence pf. Methods. 1998 Jul;15(3):243-53. doi: 10.1006/meth.1998.0628. Methods. 1998. PMID: 9735309

8

2-5A-PNA complexes: a novel class of antisense compounds.

Verheijen JC, Bayly SF, Player MR, Torrence PF, van der Marel GA, van Boom JH. Verheijen JC, et al. Among authors: torrence pf. Nucleosides Nucleotides. 1999 Jun-Jul;18(6-7):1485-6. doi: 10.1080/07328319908044761. Nucleosides Nucleotides. 1999. PMID: 10474229

9

Synthesis and RNAse L binding and activation of a 2-5A-(5')-DNA-(3')-PNA chimera, a novel potential antisense molecule.

Verheijen JC, Chen L, Bayly SF, Torrence PF, van der Marel GA, van Boom JH. Verheijen JC, et al. Among authors: torrence pf. Nucleosides Nucleotides Nucleic Acids. 2000 Oct-Dec;19(10-12):1821-30. doi: 10.1080/15257770008045463. Nucleosides Nucleotides Nucleic Acids. 2000. PMID: 11200276

10

Accelerating RNA decay through intervention of RNase L: alternative synthesis of composite 2',5'-oligoadenylate-antisense.

Torrence PF, Wang Z. Torrence PF, et al. Methods Enzymol. 2001;342:20-8. doi: 10.1016/s0076-6879(01)42532-8. Methods Enzymol. 2001. PMID: 11586893 No abstract available.

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