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Antifungal rapamycin analogues with reduced immunosuppressive activity.
Dickman DA, Ding H, Li Q, Nilius AM, Balli DJ, Ballaron SJ, Trevillyan JM, Smith ML, Seif LS, Kim K, Sarthy A, Goldman RC, Plattner JJ, Bennani YL. Dickman DA, et al. Among authors: li q. Bioorg Med Chem Lett. 2000 Jul 3;10(13):1405-8. doi: 10.1016/s0960-894x(00)00184-0. Bioorg Med Chem Lett. 2000. PMID: 10888319
Discovery, SAR, synthesis, pharmacokinetic and biochemical characterization of A-192411: a novel fungicidal lipopeptide-(I).
Wang W, Li Q, Hasvold L, Steiner B, Dickman DA, Ding H, Clairborne A, Chen HJ, Frost D, Goldman RC, Marsh K, Hui YH, Cox B, Nilius A, Balli D, Lartey P, Plattner JJ, Bennani YL. Wang W, et al. Among authors: li q. Bioorg Med Chem Lett. 2003 Feb 10;13(3):489-93. doi: 10.1016/s0960-894x(02)00978-2. Bioorg Med Chem Lett. 2003. PMID: 12565957
In vivo characterization of A-192411: a novel fungicidal lipopeptide (II).
Meulbroek JA, Nilius AM, Li Q, Wang W, Hasvold L, Steiner B, Dickman DA, Ding H, Frost D, Goldman RC, Lartey P, Plattner JJ, Bennani YL. Meulbroek JA, et al. Among authors: li q. Bioorg Med Chem Lett. 2003 Feb 10;13(3):495-7. doi: 10.1016/s0960-894x(02)00979-4. Bioorg Med Chem Lett. 2003. PMID: 12565958
In vitro activity of A-192411.29, a novel antifungal lipopeptide.
Nilius AM, Raney PM, Hensey-Rudloff DM, Wang W, Li Q, Flamm RK. Nilius AM, et al. Among authors: li q. Antimicrob Agents Chemother. 2000 May;44(5):1242-6. doi: 10.1128/AAC.44.5.1242-1246.2000. Antimicrob Agents Chemother. 2000. PMID: 10770758 Free PMC article.
Synthesis and structure-activity relationships of 2-pyridones: a novel series of potent DNA gyrase inhibitors as antibacterial agents.
Li Q, Chu DT, Claiborne A, Cooper CS, Lee CM, Raye K, Berst KB, Donner P, Wang W, Hasvold L, Fung A, Ma Z, Tufano M, Flamm R, Shen LL, Baranowski J, Nilius A, Alder J, Meulbroek J, Marsh K, Crowell D, Hui Y, Seif L, Melcher LM, Plattner JJ, et al. Li Q, et al. J Med Chem. 1996 Aug 2;39(16):3070-88. doi: 10.1021/jm960207w. J Med Chem. 1996. PMID: 8759628
Novel sulfonate analogues of combretastatin A-4: potent antimitotic agents.
Gwaltney SL 2nd, Imade HM, Barr KJ, Li Q, Gehrke L, Credo RB, Warner RB, Lee JY, Kovar P, Wang J, Nukkala MA, Zielinski NA, Frost D, Ng SC, Sham HL. Gwaltney SL 2nd, et al. Among authors: li q. Bioorg Med Chem Lett. 2001 Apr 9;11(7):871-4. doi: 10.1016/s0960-894x(01)00098-1. Bioorg Med Chem Lett. 2001. PMID: 11294380
Synthesis and biological evaluation of 2-indolyloxazolines as a new class of tubulin polymerization inhibitors. Discovery of A-289099 as an orally active antitumor agent.
Li Q, Woods KW, Claiborne A, Gwaltney SL 2nd, Barr KJ, Liu G, Gehrke L, Credo RB, Hui YH, Lee J, Warner RB, Kovar P, Nukkala MA, Zielinski NA, Tahir SK, Fitzgerald M, Kim KH, Marsh K, Frost D, Ng SC, Rosenberg S, Sham HL. Li Q, et al. Bioorg Med Chem Lett. 2002 Feb 11;12(3):465-9. doi: 10.1016/s0960-894x(01)00759-4. Bioorg Med Chem Lett. 2002. PMID: 11814821
Potent, orally active heterocycle-based combretastatin A-4 analogues: synthesis, structure-activity relationship, pharmacokinetics, and in vivo antitumor activity evaluation.
Wang L, Woods KW, Li Q, Barr KJ, McCroskey RW, Hannick SM, Gherke L, Credo RB, Hui YH, Marsh K, Warner R, Lee JY, Zielinski-Mozng N, Frost D, Rosenberg SH, Sham HL. Wang L, et al. Among authors: li q. J Med Chem. 2002 Apr 11;45(8):1697-711. doi: 10.1021/jm010523x. J Med Chem. 2002. PMID: 11931625
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