Besra GS - Search Results

1

Activation of the pro-drug ethionamide is regulated in mycobacteria.

Baulard AR, Betts JC, Engohang-Ndong J, Quan S, McAdam RA, Brennan PJ, Locht C, Besra GS. Baulard AR, et al. Among authors: besra gs. J Biol Chem. 2000 Sep 8;275(36):28326-31. doi: 10.1074/jbc.M003744200. J Biol Chem. 2000. PMID: 10869356 Free article.

2

In vivo interaction between the polyprenol phosphate mannose synthase Ppm1 and the integral membrane protein Ppm2 from Mycobacterium smegmatis revealed by a bacterial two-hybrid system.

Baulard AR, Gurcha SS, Engohang-Ndong J, Gouffi K, Locht C, Besra GS. Baulard AR, et al. Among authors: besra gs. J Biol Chem. 2003 Jan 24;278(4):2242-8. doi: 10.1074/jbc.M207922200. Epub 2002 Nov 8. J Biol Chem. 2003. PMID: 12427759 Free article.

3

Inhibition of InhA activity, but not KasA activity, induces formation of a KasA-containing complex in mycobacteria.

Kremer L, Dover LG, Morbidoni HR, Vilchèze C, Maughan WN, Baulard A, Tu SC, Honoré N, Deretic V, Sacchettini JC, Locht C, Jacobs WR Jr, Besra GS. Kremer L, et al. Among authors: besra gs. J Biol Chem. 2003 Jun 6;278(23):20547-54. doi: 10.1074/jbc.M302435200. Epub 2003 Mar 24. J Biol Chem. 2003. PMID: 12654922 Free article.

4

EthR, a repressor of the TetR/CamR family implicated in ethionamide resistance in mycobacteria, octamerizes cooperatively on its operator.

Engohang-Ndong J, Baillat D, Aumercier M, Bellefontaine F, Besra GS, Locht C, Baulard AR. Engohang-Ndong J, et al. Among authors: besra gs. Mol Microbiol. 2004 Jan;51(1):175-88. doi: 10.1046/j.1365-2958.2003.03809.x. Mol Microbiol. 2004. PMID: 14651620 Free article.

5

Thiolactomycin and related analogues as novel anti-mycobacterial agents targeting KasA and KasB condensing enzymes in Mycobacterium tuberculosis.

Kremer L, Douglas JD, Baulard AR, Morehouse C, Guy MR, Alland D, Dover LG, Lakey JH, Jacobs WR Jr, Brennan PJ, Minnikin DE, Besra GS. Kremer L, et al. Among authors: besra gs. J Biol Chem. 2000 Jun 2;275(22):16857-64. doi: 10.1074/jbc.M000569200. J Biol Chem. 2000. PMID: 10747933 Free article.

6

Biochemical characterization of acyl carrier protein (AcpM) and malonyl-CoA:AcpM transacylase (mtFabD), two major components of Mycobacterium tuberculosis fatty acid synthase II.

Kremer L, Nampoothiri KM, Lesjean S, Dover LG, Graham S, Betts J, Brennan PJ, Minnikin DE, Locht C, Besra GS. Kremer L, et al. Among authors: besra gs. J Biol Chem. 2001 Jul 27;276(30):27967-74. doi: 10.1074/jbc.M103687200. Epub 2001 May 23. J Biol Chem. 2001. PMID: 11373295 Free article.

7

Unique mechanism of action of the thiourea drug isoxyl on Mycobacterium tuberculosis.

Phetsuksiri B, Jackson M, Scherman H, McNeil M, Besra GS, Baulard AR, Slayden RA, DeBarber AE, Barry CE 3rd, Baird MS, Crick DC, Brennan PJ. Phetsuksiri B, et al. Among authors: besra gs. J Biol Chem. 2003 Dec 26;278(52):53123-30. doi: 10.1074/jbc.M311209200. Epub 2003 Oct 14. J Biol Chem. 2003. PMID: 14559907 Free PMC article.

8

Biosynthesis of the linkage region of the mycobacterial cell wall.

Mikusová K, Mikus M, Besra GS, Hancock I, Brennan PJ. Mikusová K, et al. Among authors: besra gs. J Biol Chem. 1996 Mar 29;271(13):7820-8. doi: 10.1074/jbc.271.13.7820. J Biol Chem. 1996. PMID: 8631826 Free article.

9

Antimycobacterial activities of isoxyl and new derivatives through the inhibition of mycolic acid synthesis.

Phetsuksiri B, Baulard AR, Cooper AM, Minnikin DE, Douglas JD, Besra GS, Brennan PJ. Phetsuksiri B, et al. Among authors: besra gs. Antimicrob Agents Chemother. 1999 May;43(5):1042-51. doi: 10.1128/AAC.43.5.1042. Antimicrob Agents Chemother. 1999. PMID: 10223912 Free PMC article.

10

The pimB gene of Mycobacterium tuberculosis encodes a mannosyltransferase involved in lipoarabinomannan biosynthesis.

Schaeffer ML, Khoo KH, Besra GS, Chatterjee D, Brennan PJ, Belisle JT, Inamine JM. Schaeffer ML, et al. Among authors: besra gs. J Biol Chem. 1999 Oct 29;274(44):31625-31. doi: 10.1074/jbc.274.44.31625. J Biol Chem. 1999. PMID: 10531370 Free article.

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