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Page 1
(R,S)-4-phosphonophenylglycine, a potent and selective group III metabotropic glutamate receptor agonist, is anticonvulsive and neuroprotective in vivo.
Gasparini F, Bruno V, Battaglia G, Lukic S, Leonhardt T, Inderbitzin W, Laurie D, Sommer B, Varney MA, Hess SD, Johnson EC, Kuhn R, Urwyler S, Sauer D, Portet C, Schmutz M, Nicoletti F, Flor PJ. Gasparini F, et al. Among authors: inderbitzin w. J Pharmacol Exp Ther. 1999 Jun;289(3):1678-87. J Pharmacol Exp Ther. 1999. PMID: 10336568
Chiral resolution, pharmacological characterization, and receptor docking of the noncompetitive mGlu1 receptor antagonist (+/-)-2-hydroxyimino- 1a, 2-dihydro-1H-7-oxacyclopropa[b]naphthalene-7a-carboxylic acid ethyl ester.
Ott D, Floersheim P, Inderbitzin W, Stoehr N, Francotte E, Lecis G, Richert P, Rihs G, Flor PJ, Kuhn R, Gasparini F. Ott D, et al. Among authors: inderbitzin w. J Med Chem. 2000 Nov 16;43(23):4428-36. doi: 10.1021/jm0009944. J Med Chem. 2000. PMID: 11087567
Selective activation of mGlu4 metabotropic glutamate receptors is protective against excitotoxic neuronal death.
Bruno V, Battaglia G, Ksiazek I, van der Putten H, Catania MV, Giuffrida R, Lukic S, Leonhardt T, Inderbitzin W, Gasparini F, Kuhn R, Hampson DR, Nicoletti F, Flor PJ. Bruno V, et al. Among authors: inderbitzin w. J Neurosci. 2000 Sep 1;20(17):6413-20. doi: 10.1523/JNEUROSCI.20-17-06413.2000. J Neurosci. 2000. PMID: 10964947 Free PMC article.