Laughton K - Search Results

1

Construction, production, and characterization of humanized anti-Lewis Y monoclonal antibody 3S193 for targeted immunotherapy of solid tumors.

Scott AM, Geleick D, Rubira M, Clarke K, Nice EC, Smyth FE, Stockert E, Richards EC, Carr FJ, Harris WJ, Armour KL, Rood J, Kypridis A, Kronina V, Murphy R, Lee FT, Liu Z, Kitamura K, Ritter G, Laughton K, Hoffman E, Burgess AW, Old LJ. Scott AM, et al. Among authors: laughton k. Cancer Res. 2000 Jun 15;60(12):3254-61. Cancer Res. 2000. PMID: 10866319

2

Brain beta-amyloid accumulation in transgenic mice expressing mutant superoxide dismutase 1.

Turner BJ, Li QX, Laughton KM, Masters CL, Lopes EC, Atkin JD, Cheema SS. Turner BJ, et al. Neurochem Res. 2004 Dec;29(12):2281-6. doi: 10.1007/s11064-004-7037-z. Neurochem Res. 2004. PMID: 15672551

3

Restored degradation of the Alzheimer's amyloid-beta peptide by targeting amyloid formation.

Crouch PJ, Tew DJ, Du T, Nguyen DN, Caragounis A, Filiz G, Blake RE, Trounce IA, Soon CP, Laughton K, Perez KA, Li QX, Cherny RA, Masters CL, Barnham KJ, White AR. Crouch PJ, et al. Among authors: laughton k. J Neurochem. 2009 Mar;108(5):1198-207. doi: 10.1111/j.1471-4159.2009.05870.x. Epub 2009 Jan 7. J Neurochem. 2009. PMID: 19141082 Free article.

4

Activation of epidermal growth factor receptor by metal-ligand complexes decreases levels of extracellular amyloid beta peptide.

Price KA, Filiz G, Caragounis A, Du T, Laughton KM, Masters CL, Sharples RA, Hill AF, Li QX, Donnelly PS, Barnham KJ, Crouch PJ, White AR. Price KA, et al. Int J Biochem Cell Biol. 2008;40(9):1901-17. doi: 10.1016/j.biocel.2008.01.033. Epub 2008 Feb 12. Int J Biochem Cell Biol. 2008. PMID: 18346929

5

Chronic exposure to high levels of zinc or copper has little effect on brain metal homeostasis or Abeta accumulation in transgenic APP-C100 mice.

Maynard CJ, Cappai R, Volitakis I, Laughton KM, Masters CL, Bush AI, Li QX. Maynard CJ, et al. Cell Mol Neurobiol. 2009 Jul;29(5):757-67. doi: 10.1007/s10571-009-9401-7. Epub 2009 Apr 21. Cell Mol Neurobiol. 2009. PMID: 19381799

6

APP intracellular domain is increased and soluble Abeta is reduced with diet-induced hypercholesterolemia in a transgenic mouse model of Alzheimer disease.

George AJ, Holsinger RM, McLean CA, Laughton KM, Beyreuther K, Evin G, Masters CL, Li QX. George AJ, et al. Among authors: laughton km. Neurobiol Dis. 2004 Jun;16(1):124-32. doi: 10.1016/j.nbd.2004.01.009. Neurobiol Dis. 2004. PMID: 15207269

7

Overexpression of Abeta is associated with acceleration of onset of motor impairment and superoxide dismutase 1 aggregation in an amyotrophic lateral sclerosis mouse model.

Li QX, Mok SS, Laughton KM, McLean CA, Volitakis I, Cherny RA, Cheung NS, White AR, Masters CL. Li QX, et al. Aging Cell. 2006 Apr;5(2):153-65. doi: 10.1111/j.1474-9726.2006.00200.x. Aging Cell. 2006. PMID: 16626394 Free article.

8

Serum matrix metalloproteinase-9 activity is dysregulated with disease progression in the mutant SOD1 transgenic mice.

Soon CP, Crouch PJ, Turner BJ, McLean CA, Laughton KM, Atkin JD, Masters CL, White AR, Li QX. Soon CP, et al. Among authors: laughton km. Neuromuscul Disord. 2010 Apr;20(4):260-6. doi: 10.1016/j.nmd.2009.11.015. Epub 2010 Jan 25. Neuromuscul Disord. 2010. PMID: 20097566

9

Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta.

Adlard PA, Cherny RA, Finkelstein DI, Gautier E, Robb E, Cortes M, Volitakis I, Liu X, Smith JP, Perez K, Laughton K, Li QX, Charman SA, Nicolazzo JA, Wilkins S, Deleva K, Lynch T, Kok G, Ritchie CW, Tanzi RE, Cappai R, Masters CL, Barnham KJ, Bush AI. Adlard PA, et al. Among authors: laughton k. Neuron. 2008 Jul 10;59(1):43-55. doi: 10.1016/j.neuron.2008.06.018. Neuron. 2008. PMID: 18614028 Free article.

10

Plasma amyloid-beta as a biomarker in Alzheimer's disease: the AIBL study of aging.

Lui JK, Laws SM, Li QX, Villemagne VL, Ames D, Brown B, Bush AI, De Ruyck K, Dromey J, Ellis KA, Faux NG, Foster J, Fowler C, Gupta V, Hudson P, Laughton K, Masters CL, Pertile K, Rembach A, Rimajova M, Rodrigues M, Rowe CC, Rumble R, Szoeke C, Taddei K, Taddei T, Trounson B, Ward V, Martins RN, AIBL Research Group. Lui JK, et al. Among authors: laughton k. J Alzheimers Dis. 2010;20(4):1233-42. doi: 10.3233/JAD-2010-090249. J Alzheimers Dis. 2010. PMID: 20413897

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