Topal MD - Search Results

1

Crystal structure of NaeI-an evolutionary bridge between DNA endonuclease and topoisomerase.

Huai Q, Colandene JD, Chen Y, Luo F, Zhao Y, Topal MD, Ke H. Huai Q, et al. Among authors: topal md. EMBO J. 2000 Jun 15;19(12):3110-8. doi: 10.1093/emboj/19.12.3110. EMBO J. 2000. PMID: 10856254 Free PMC article.

2

The domain organization of NaeI endonuclease: separation of binding and catalysis.

Colandene JD, Topal MD. Colandene JD, et al. Among authors: topal md. Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):3531-6. doi: 10.1073/pnas.95.7.3531. Proc Natl Acad Sci U S A. 1998. PMID: 9520400 Free PMC article.

3

Evidence for mutations that break communication between the Endo and Topo domains in NaeI endonuclease/topoisomerase.

Colandene JD, Topal MD. Colandene JD, et al. Among authors: topal md. Biochemistry. 2000 Nov 14;39(45):13703-7. doi: 10.1021/bi001812a. Biochemistry. 2000. PMID: 11076509

4

Structure of NaeI-DNA complex reveals dual-mode DNA recognition and complete dimer rearrangement.

Huai Q, Colandene JD, Topal MD, Ke H. Huai Q, et al. Among authors: topal md. Nat Struct Biol. 2001 Aug;8(8):665-9. doi: 10.1038/90366. Nat Struct Biol. 2001. PMID: 11473254

5

Amino acid substitutions at position 43 of NaeI endonuclease. Evidence for changes in NaeI structure.

Carrick KL, Topal MD. Carrick KL, et al. Among authors: topal md. J Biol Chem. 2003 Mar 14;278(11):9733-9. doi: 10.1074/jbc.M209192200. Epub 2003 Jan 8. J Biol Chem. 2003. PMID: 12519752 Free article.

6

Effects on NaeI-DNA recognition of the leucine to lysine substitution that transforms restriction endonuclease NaeI to a topoisomerase: a model for restriction endonuclease evolution.

Jo K, Topal MD. Jo K, et al. Among authors: topal md. Nucleic Acids Res. 1996 Nov 1;24(21):4171-5. doi: 10.1093/nar/24.21.4171. Nucleic Acids Res. 1996. PMID: 8932368 Free PMC article.

7

Step-wise DNA relaxation and decatenation by NaeI-43K.

Jo K, Topal MD. Jo K, et al. Among authors: topal md. Nucleic Acids Res. 1998 May 15;26(10):2380-4. doi: 10.1093/nar/26.10.2380. Nucleic Acids Res. 1998. PMID: 9580689 Free PMC article.

8

DNA topoisomerase and recombinase activities in Nae I restriction endonuclease.

Jo K, Topal MD. Jo K, et al. Among authors: topal md. Science. 1995 Mar 24;267(5205):1817-20. doi: 10.1126/science.7892605. Science. 1995. PMID: 7892605

9

Changing a leucine to a lysine residue makes NaeI endonuclease hypersensitive to DNA intercalative drugs.

Jo K, Topal MD. Jo K, et al. Among authors: topal md. Biochemistry. 1996 Aug 6;35(31):10014-8. doi: 10.1021/bi9604542. Biochemistry. 1996. PMID: 8756463

10

NaeI endonuclease binding to pBR322 DNA induces looping.

Topal MD, Thresher RJ, Conrad M, Griffith J. Topal MD, et al. Biochemistry. 1991 Feb 19;30(7):2006-10. doi: 10.1021/bi00221a038. Biochemistry. 1991. PMID: 1847081

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