Goodwin B - Search Results

1

St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor.

Moore LB, Goodwin B, Jones SA, Wisely GB, Serabjit-Singh CJ, Willson TM, Collins JL, Kliewer SA. Moore LB, et al. Among authors: goodwin b. Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):7500-2. doi: 10.1073/pnas.130155097. Proc Natl Acad Sci U S A. 2000. PMID: 10852961 Free PMC article.

2

The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism.

Kliewer SA, Goodwin B, Willson TM. Kliewer SA, et al. Among authors: goodwin b. Endocr Rev. 2002 Oct;23(5):687-702. doi: 10.1210/er.2001-0038. Endocr Rev. 2002. PMID: 12372848 Review.

3

Nuclear receptor regulation of genes involved in bile acid metabolism.

Moore JT, Goodwin B, Willson TM, Kliewer SA. Moore JT, et al. Among authors: goodwin b. Crit Rev Eukaryot Gene Expr. 2002;12(2):119-35. doi: 10.1615/critreveukaryotgeneexpr.v12.i2.30. Crit Rev Eukaryot Gene Expr. 2002. PMID: 12434926 Review.

4

Identification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptor.

Goodwin B, Gauthier KC, Umetani M, Watson MA, Lochansky MI, Collins JL, Leitersdorf E, Mangelsdorf DJ, Kliewer SA, Repa JJ. Goodwin B, et al. Proc Natl Acad Sci U S A. 2003 Jan 7;100(1):223-8. doi: 10.1073/pnas.0237082100. Epub 2002 Dec 30. Proc Natl Acad Sci U S A. 2003. PMID: 12509506 Free PMC article.

5

Regulation of cyp3a gene transcription by the pregnane x receptor.

Goodwin B, Redinbo MR, Kliewer SA. Goodwin B, et al. Annu Rev Pharmacol Toxicol. 2002;42:1-23. doi: 10.1146/annurev.pharmtox.42.111901.111051. Annu Rev Pharmacol Toxicol. 2002. PMID: 11807162 Review.

6

Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands.

Moore LB, Parks DJ, Jones SA, Bledsoe RK, Consler TG, Stimmel JB, Goodwin B, Liddle C, Blanchard SG, Willson TM, Collins JL, Kliewer SA. Moore LB, et al. Among authors: goodwin b. J Biol Chem. 2000 May 19;275(20):15122-7. doi: 10.1074/jbc.M001215200. J Biol Chem. 2000. PMID: 10748001 Free article.

7

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity.

Staudinger JL, Goodwin B, Jones SA, Hawkins-Brown D, MacKenzie KI, LaTour A, Liu Y, Klaassen CD, Brown KK, Reinhard J, Willson TM, Koller BH, Kliewer SA. Staudinger JL, et al. Among authors: goodwin b. Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3369-74. doi: 10.1073/pnas.051551698. Proc Natl Acad Sci U S A. 2001. PMID: 11248085 Free PMC article.

8

Regulation of the human CYP2B6 gene by the nuclear pregnane X receptor.

Goodwin B, Moore LB, Stoltz CM, McKee DD, Kliewer SA. Goodwin B, et al. Mol Pharmacol. 2001 Sep;60(3):427-31. Mol Pharmacol. 2001. PMID: 11502872

9

Induction of cytochrome P450 3A4 in primary human hepatocytes and activation of the human pregnane X receptor by tamoxifen and 4-hydroxytamoxifen.

Desai PB, Nallani SC, Sane RS, Moore LB, Goodwin BJ, Buckley DJ, Buckley AR. Desai PB, et al. Among authors: goodwin bj. Drug Metab Dispos. 2002 May;30(5):608-12. doi: 10.1124/dmd.30.5.608. Drug Metab Dispos. 2002. PMID: 11950795

10

Recent advances in liver X receptor biology and chemistry.

Goodwin BJ, Zuercher WJ, Collins JL. Goodwin BJ, et al. Curr Top Med Chem. 2008;8(9):781-91. doi: 10.2174/156802608784535075. Curr Top Med Chem. 2008. PMID: 18537688 Review.

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