Parniak MA - Search Results

1

Synthesis and biophysical properties of arabinonucleic acids (ANA): circular dichroic spectra, melting temperatures, and ribonuclease H susceptibility of ANA.RNA hybrid duplexes.

Noronha AM, Wilds CJ, Lok CN, Viazovkina K, Arion D, Parniak MA, Damha MJ. Noronha AM, et al. Among authors: parniak ma. Biochemistry. 2000 Jun 20;39(24):7050-62. doi: 10.1021/bi000280v. Biochemistry. 2000. PMID: 10852702

2

Potent gene-specific inhibitory properties of mixed-backbone antisense oligonucleotides comprised of 2'-deoxy-2'-fluoro-D-arabinose and 2'-deoxyribose nucleotides.

Lok CN, Viazovkina E, Min KL, Nagy E, Wilds CJ, Damha MJ, Parniak MA. Lok CN, et al. Among authors: parniak ma. Biochemistry. 2002 Mar 12;41(10):3457-67. doi: 10.1021/bi0115075. Biochemistry. 2002. PMID: 11876654

3

Inhibitory potency of R-region specific antisense oligonucleotides against in vitro DNA polymerization and template-switching reactions catalysed by HIV-1 reverse transcriptase.

Borkow G, Arion D, Noronha A, Scartozzi M, Damha MJ, Parniak MA. Borkow G, et al. Among authors: parniak ma. Int J Biochem Cell Biol. 1997 Nov;29(11):1285-95. doi: 10.1016/s1357-2725(97)00067-8. Int J Biochem Cell Biol. 1997. PMID: 9451826

4

Physicochemical and biochemical properties of 2',5'-linked RNA and 2',5'-RNA:3',5'-RNA "hybrid" duplexes.

Wasner M, Arion D, Borkow G, Noronha A, Uddin AH, Parniak MA, Damha MJ. Wasner M, et al. Among authors: parniak ma. Biochemistry. 1998 May 19;37(20):7478-86. doi: 10.1021/bi980160b. Biochemistry. 1998. PMID: 9585561

5

Oligonucleotides comprised of alternating 2'-deoxy-2'-fluoro-beta-D-arabinonucleosides and D-2'-deoxyribonucleosides (2'F-ANA/DNA 'altimers') induce efficient RNA cleavage mediated by RNase H.

Min KL, Viazovkina E, Galarneau A, Parniak MA, Damha MJ. Min KL, et al. Among authors: parniak ma. Bioorg Med Chem Lett. 2002 Sep 16;12(18):2651-4. doi: 10.1016/s0960-894x(02)00439-0. Bioorg Med Chem Lett. 2002. PMID: 12182880

6

Efficient RNase H-directed cleavage of RNA promoted by antisense DNA or 2'F-ANA constructs containing acyclic nucleotide inserts.

Mangos MM, Min KL, Viazovkina E, Galarneau A, Elzagheid MI, Parniak MA, Damha MJ. Mangos MM, et al. Among authors: parniak ma. J Am Chem Soc. 2003 Jan 22;125(3):654-61. doi: 10.1021/ja025557o. J Am Chem Soc. 2003. PMID: 12526664

7

Synergistic inhibition of HIV-1 reverse transcriptase DNA polymerase activity and virus replication in vitro by combinations of carboxanilide nonnucleoside compounds.

Fletcher RS, Arion D, Borkow G, Wainberg MA, Dmitrienko GI, Parniak MA. Fletcher RS, et al. Among authors: parniak ma. Biochemistry. 1995 Aug 15;34(32):10106-12. doi: 10.1021/bi00032a002. Biochemistry. 1995. PMID: 7543775

8

Inhibition of the ribonuclease H and DNA polymerase activities of HIV-1 reverse transcriptase by N-(4-tert-butylbenzoyl)-2-hydroxy-1-naphthaldehyde hydrazone.

Borkow G, Fletcher RS, Barnard J, Arion D, Motakis D, Dmitrienko GI, Parniak MA. Borkow G, et al. Among authors: parniak ma. Biochemistry. 1997 Mar 18;36(11):3179-85. doi: 10.1021/bi9624696. Biochemistry. 1997. PMID: 9115994

9

Phenotypic mechanism of HIV-1 resistance to 3'-azido-3'-deoxythymidine (AZT): increased polymerization processivity and enhanced sensitivity to pyrophosphate of the mutant viral reverse transcriptase.

Arion D, Kaushik N, McCormick S, Borkow G, Parniak MA. Arion D, et al. Among authors: parniak ma. Biochemistry. 1998 Nov 10;37(45):15908-17. doi: 10.1021/bi981200e. Biochemistry. 1998. PMID: 9843396

10

Effect of substituting arabinonucleosides for deoxynucleotides in the DNA priming strand on the polymerase action of HIV-1 RT.

Noronha AM, Arion D, Parniak MA, Damha MJ. Noronha AM, et al. Among authors: parniak ma. Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):1205-9. doi: 10.1081/NCN-100002520. Nucleosides Nucleotides Nucleic Acids. 2001. PMID: 11562987

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