Romoff T - Search Results

1

3-(Diethoxyphosphoryloxy)-1,2,3-benzotriazin-4(3H)-one (DEPBT): a new coupling reagent with remarkable resistance to racemization.

Li H, Jiang X, Ye YH, Fan C, Romoff T, Goodman M. Li H, et al. Among authors: romoff t. Org Lett. 1999 Jul 15;1(1):91-3. doi: 10.1021/ol990573k. Org Lett. 1999. PMID: 10822541

2

Urethane-protected N-carboxyanhydrides (UNCAs) as unique reactants for the study of intrinsic racemization tendencies in peptide synthesis.

Romoff TT, Tran TA, Goodman M. Romoff TT, et al. J Pept Res. 1997 Apr;49(4):281-92. doi: 10.1111/j.1399-3011.1997.tb01128.x. J Pept Res. 1997. PMID: 9176811

3

Rapid and efficient syntheses of tryptophans using a continuous-flow quaternization-substitution reaction of gramines with a chiral nucleophilic glycine equivalent.

Koiwa D, Ohira M, Hiramatsu T, Abe H, Kawamoto T, Ishihara Y, Ignacio B, Mansour N, Romoff T. Koiwa D, et al. Among authors: romoff t. Org Biomol Chem. 2022 Nov 2;20(42):8331-8340. doi: 10.1039/d2ob01682f. Org Biomol Chem. 2022. PMID: 36250233

4

Development of Hamari Ligands for Practical Asymmetric Synthesis of Tailor-Made Amino Acids.

Han J, Romoff TT, Moriwaki H, Konno H, Soloshonok VA. Han J, et al. Among authors: romoff tt. ACS Omega. 2019 Nov 7;4(21):18942-18947. doi: 10.1021/acsomega.9b02940. eCollection 2019 Nov 19. ACS Omega. 2019. PMID: 31763515 Free PMC article. Review.

5

Synthesis, in vitro and in vivo activity of thiamine antagonist transketolase inhibitors.

Thomas AA, Le Huerou Y, De Meese J, Gunawardana I, Kaplan T, Romoff TT, Gonzales SS, Condroski K, Boyd SA, Ballard J, Bernat B, DeWolf W, Han M, Lee P, Lemieux C, Pedersen R, Pheneger J, Poch G, Smith D, Sullivan F, Weiler S, Wright SK, Lin J, Brandhuber B, Vigers G. Thomas AA, et al. Among authors: romoff tt. Bioorg Med Chem Lett. 2008 Mar 15;18(6):2206-10. doi: 10.1016/j.bmcl.2007.11.101. Epub 2007 Dec 3. Bioorg Med Chem Lett. 2008. PMID: 18267359

6

Non-charged thiamine analogs as inhibitors of enzyme transketolase.

Thomas AA, De Meese J, Le Huerou Y, Boyd SA, Romoff TT, Gonzales SS, Gunawardana I, Kaplan T, Sullivan F, Condroski K, Lyssikatos JP, Aicher TD, Ballard J, Bernat B, DeWolf W, Han M, Lemieux C, Smith D, Weiler S, Wright SK, Vigers G, Brandhuber B. Thomas AA, et al. Among authors: romoff tt. Bioorg Med Chem Lett. 2008 Jan 15;18(2):509-12. doi: 10.1016/j.bmcl.2007.11.098. Epub 2007 Dec 3. Bioorg Med Chem Lett. 2008. PMID: 18182286

7

Prodrug thiamine analogs as inhibitors of the enzyme transketolase.

Le Huerou Y, Gunawardana I, Thomas AA, Boyd SA, de Meese J, Dewolf W, Gonzales SS, Han M, Hayter L, Kaplan T, Lemieux C, Lee P, Pheneger J, Poch G, Romoff TT, Sullivan F, Weiler S, Wright SK, Lin J. Le Huerou Y, et al. Among authors: romoff tt. Bioorg Med Chem Lett. 2008 Jan 15;18(2):505-8. doi: 10.1016/j.bmcl.2007.11.100. Epub 2007 Dec 3. Bioorg Med Chem Lett. 2008. PMID: 18083562

8

The in vitro pharmacological profile of SK&F 106760, a novel GPIIB/IIIA antagonist.

Nichols AJ, Vasko JA, Valocik RE, Kopaciewicz LJ, Storer BL, Ali FE, Romoff T, Calvo R, Samanen JM. Nichols AJ, et al. Among authors: romoff t. Thromb Res. 1994 Jul 15;75(2):143-56. doi: 10.1016/0049-3848(94)90063-9. Thromb Res. 1994. PMID: 7974388

9

Conformationally constrained peptides and semipeptides derived from RGD as potent inhibitors of the platelet fibrinogen receptor and platelet aggregation.

Ali FE, Bennett DB, Calvo RR, Elliott JD, Hwang SM, Ku TW, Lago MA, Nichols AJ, Romoff TT, Shah DH, et al. Ali FE, et al. Among authors: romoff tt. J Med Chem. 1994 Mar 18;37(6):769-80. doi: 10.1021/jm00032a009. J Med Chem. 1994. PMID: 8145226

10

Development of a small RGD peptide fibrinogen receptor antagonist with potent antiaggregatory activity in vitro.

Samanen J, Ali F, Romoff T, Calvo R, Sorenson E, Vasko J, Storer B, Berry D, Bennett D, Strohsacker M, et al. Samanen J, et al. Among authors: romoff t. J Med Chem. 1991 Oct;34(10):3114-25. doi: 10.1021/jm00114a022. J Med Chem. 1991. PMID: 1920361

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