Doyle E - Search Results

1

Phase I pharmacologic study of oral topotecan and intravenous cisplatin: sequence-dependent hematologic side effects.

de Jonge MJ, Loos WJ, Gelderblom H, Planting AS, van der Burg ME, Sparreboom A, Brouwer E, van Beurden V, Mantel MA, Doyle E, Hearn S, Ross G, Verweij J. de Jonge MJ, et al. Among authors: doyle e. J Clin Oncol. 2000 May;18(10):2104-15. doi: 10.1200/JCO.2000.18.10.2104. J Clin Oncol. 2000. PMID: 10811676 Clinical Trial.

2

Phase I and pharmacologic study of the combination of paclitaxel, cisplatin, and topotecan administered intravenously every 21 days as first-line therapy in patients with advanced ovarian cancer.

Herben VM, Panday VR, Richel DJ, Schellens JH, van der Vange N, Rosing H, Beusenberg FD, Hearn S, Doyle E, Beijnen JH, ten Bokkel Huinink WW. Herben VM, et al. Among authors: doyle e. J Clin Oncol. 1999 Mar;17(3):747-55. doi: 10.1200/JCO.1999.17.3.747. J Clin Oncol. 1999. PMID: 10071262 Clinical Trial.

3

Oral topotecan: bioavailablity and effect of food co-administration.

Herben VM, Rosing H, ten Bokkel Huinink WW, van Zomeren DM, Batchelor D, Doyle E, Beusenberg FD, Beijnen JH, Schellens JH. Herben VM, et al. Among authors: doyle e. Br J Cancer. 1999 Jul;80(9):1380-6. doi: 10.1038/sj.bjc.6690532. Br J Cancer. 1999. PMID: 10424739 Free PMC article. Clinical Trial.

4

O-glucuronidation, a newly identified metabolic pathway for topotecan and N-desmethyl topotecan.

Rosing H, van Zomeren DM, Doyle E, Bult A, Beijnen JH. Rosing H, et al. Among authors: doyle e. Anticancer Drugs. 1998 Aug;9(7):587-92. doi: 10.1097/00001813-199808000-00002. Anticancer Drugs. 1998. PMID: 9773801

5

Pretreatment with ranitidine does not reduce the bioavailability of orally administered topotecan.

Akhtar S, Beckman RA, Mould DR, Doyle E, Fields SZ, Wright J. Akhtar S, et al. Among authors: doyle e. Cancer Chemother Pharmacol. 2000;46(3):204-10. doi: 10.1007/s002800000141. Cancer Chemother Pharmacol. 2000. PMID: 11021737 Clinical Trial.

6

Quantification of topotecan and its metabolite N-desmethyltopotecan in human plasma, urine and faeces by high-performance liquid chromatographic methods.

Rosing H, van Zomeren DM, Doyle E, ten Bokkel WW, Schellens JH, Bult A, Beijnen JH. Rosing H, et al. Among authors: doyle e. J Chromatogr B Biomed Sci Appl. 1999 Apr 30;727(1-2):191-203. doi: 10.1016/s0378-4347(99)00078-x. J Chromatogr B Biomed Sci Appl. 1999. PMID: 10360438

7

The impact of column temperature in the high performance liquid chromatographic analysis of topotecan in rat and dog plasma.

Rosing H, Doyle E, Beijnen JH. Rosing H, et al. Among authors: doyle e. J Pharm Biomed Anal. 1996 Nov;15(2):279-86. doi: 10.1016/0731-7085(96)01838-9. J Pharm Biomed Anal. 1996. PMID: 8933430

8

High-performance liquid chromatographic determination of the novel antitumour drug topotecan and topotecan as the total of the lactone plus carboxylate forms, in human plasma.

Rosing H, Doyle E, Davies BE, Beijnen JH. Rosing H, et al. Among authors: doyle e. J Chromatogr B Biomed Appl. 1995 Jun 9;668(1):107-15. doi: 10.1016/0378-4347(95)00054-m. J Chromatogr B Biomed Appl. 1995. PMID: 7550966

9

Isosorbide dinitrate plasma concentrations and bioavailability in human subjects after administration of standard oral and sublingual formulations.

Chasseaud LF, Darragh A, Doyle E, Lambe RF, Taylor T. Chasseaud LF, et al. Among authors: doyle e. J Pharm Sci. 1984 May;73(5):699-701. doi: 10.1002/jps.2600730530. J Pharm Sci. 1984. PMID: 6737249

10

Determination of the polar drug dimiracetam in human plasma and serum by column-switching high-performance liquid chromatography.

Torchio L, Lombardi F, Visconti M, Doyle E. Torchio L, et al. Among authors: doyle e. J Chromatogr B Biomed Appl. 1995 Apr 7;666(1):169-77. doi: 10.1016/0378-4347(94)00564-l. J Chromatogr B Biomed Appl. 1995. PMID: 7655615

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