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Page 1
PD 142676 (CI 1002), a novel anticholinesterase and muscarinic antagonist.
Emmerling MR, Gregor VE, Schwarz RD, Scholten JD, Callahan MJ, Lee C, Moore CJ, Raby C, Lipinski WJ, Davis RE. Emmerling MR, et al. Among authors: schwarz rd. Mol Neurobiol. 1994 Aug-Dec;9(1-3):93-106. doi: 10.1007/BF02816108. Mol Neurobiol. 1994. PMID: 7888109
CI-1017, a functionally M1-selective muscarinic agonist: design, synthesis, and preclinical pharmacology.
Tecle H, Schwarz RD, Barrett SD, Callahan MJ, Caprathe BW, Davis RE, Doyle P, Emmerling M, Lauffer DJ, Mirzadegan T, Moreland DW, Lipiniski W, Nelson C, Raby C, Spencer C, Spiegel K, Thomas AJ, Jaen JC. Tecle H, et al. Among authors: schwarz rd. Pharm Acta Helv. 2000 Mar;74(2-3):141-8. doi: 10.1016/s0031-6865(99)00027-8. Pharm Acta Helv. 2000. PMID: 10812951
Design and synthesis of m1-selective muscarinic agonists: (R)-(-)-(Z)-1-Azabicyclo[2.2.1]heptan-3-one, O-(3-(3'-methoxyphenyl)-2-propynyl)oxime maleate (CI-1017), a functionally m1-selective muscarinic agonist.
Tecle H, Barrett SD, Lauffer DJ, Augelli-Szafran C, Brann MR, Callahan MJ, Caprathe BW, Davis RE, Doyle PD, Eubanks D, Lipiniski W, Mirzadegan T, Moos WH, Moreland DW, Nelson CB, Pavia MR, Raby C, Schwarz RD, Spencer CJ, Thomas AJ, Jaen JC. Tecle H, et al. Among authors: schwarz rd. J Med Chem. 1998 Jul 2;41(14):2524-36. doi: 10.1021/jm960683m. J Med Chem. 1998. PMID: 9651157
Next generation tacrine.
Schwarz RD, Davis RE, Gracon S, Hoover T, Moos WH, Pavia MR. Schwarz RD, et al. Neurobiol Aging. 1991 Mar-Apr;12(2):185-7. doi: 10.1016/0197-4580(91)90060-w. Neurobiol Aging. 1991. PMID: 2052133 Review. No abstract available.
Cognition activators.
Moos WH, Davis RE, Schwarz RD, Gamzu ER. Moos WH, et al. Among authors: schwarz rd. Med Res Rev. 1988 Jul-Sep;8(3):353-91. doi: 10.1002/med.2610080303. Med Res Rev. 1988. PMID: 3043116 Review. No abstract available.
51 results