Keizer HJ - Search Results

1

Increased local cytostatic drug exposure by isolated hepatic perfusion: a phase I clinical and pharmacologic evaluation of treatment with high dose melphalan in patients with colorectal cancer confined to the liver.

Vahrmeijer AL, van Dierendonck JH, Keizer HJ, Beijnen JH, Tollenaar RA, Pijl ME, Marinelli A, Kuppen PJ, van Bockel JH, Mulder GJ, van de Velde CJ. Vahrmeijer AL, et al. Among authors: keizer hj. Br J Cancer. 2000 May;82(9):1539-46. doi: 10.1054/bjoc.2000.1175. Br J Cancer. 2000. PMID: 10789721 Free PMC article. Clinical Trial.

2

Lack of glutathione conjugation of melphalan in the isolated in situ liver perfusion in humans.

Vahrmeijer AL, Snel CA, Steenvoorden DP, Beijnen JH, Pang KS, Schutrups J, Tirona R, Keizer HJ, van Dierendonck JH, van de Velde CJ, Mulder GJ. Vahrmeijer AL, et al. Among authors: keizer hj. Cancer Res. 1996 Oct 15;56(20):4709-14. Cancer Res. 1996. PMID: 8840988 Clinical Trial.

3

Isolated liver perfusion with mitomycin C in the treatment of colorectal cancer metastases confined to the liver.

Marinelli A, de Brauw LM, Beerman H, Keizer HJ, van Bockel JH, Tjaden UR, van de Velde CJ. Marinelli A, et al. Among authors: keizer hj. Jpn J Clin Oncol. 1996 Oct;26(5):341-50. doi: 10.1093/oxfordjournals.jjco.a023243. Jpn J Clin Oncol. 1996. PMID: 8895675 Clinical Trial.

4

Chemotherapy for operable gastric cancer: results of the Dutch randomised FAMTX trial. The Dutch Gastric Cancer Group (DGCG).

Songun I, Keizer HJ, Hermans J, Klementschitsch P, de Vries JE, Wils JA, van der Bijl J, van Krieken JH, van de Velde CJ. Songun I, et al. Among authors: keizer hj. Eur J Cancer. 1999 Apr;35(4):558-62. doi: 10.1016/s0959-8049(98)00429-8. Eur J Cancer. 1999. PMID: 10492627 Clinical Trial.

5

Evaluation of the autoinduction of ifosfamide metabolism by a population pharmacokinetic approach using NONMEM.

Kerbusch T, Huitema AD, Ouwerkerk J, Keizer HJ, Mathôt RA, Schellens JH, Beijnen JH. Kerbusch T, et al. Among authors: keizer hj. Br J Clin Pharmacol. 2000 Jun;49(6):555-61. doi: 10.1046/j.1365-2125.2000.00217.x. Br J Clin Pharmacol. 2000. PMID: 10848719 Free PMC article. Clinical Trial.

6

Influence of dose and infusion duration on pharmacokinetics of ifosfamide and metabolites.

Kerbusch T, Mathôt RA, Keizer HJ, Kaijser GP, Schellens JH, Beijnen JH. Kerbusch T, et al. Among authors: keizer hj. Drug Metab Dispos. 2001 Jul;29(7):967-75. Drug Metab Dispos. 2001. PMID: 11408362

7

In vivo characterization and modulation of the glutathione/glutathione S-transferase system in cancer patients.

Mulders TM, Keizer HJ, Breimer DD, Mulder GJ. Mulders TM, et al. Among authors: keizer hj. Drug Metab Rev. 1995;27(1-2):191-229. doi: 10.3109/03602539509029823. Drug Metab Rev. 1995. PMID: 7641576 Review. No abstract available.

8

Pharmacokinetics of ifosfamide, 2- and 3-dechloroethylifosfamide in plasma and urine of cancer patients treated with a 10-day continuous infusion of ifosfamide.

Kaijser GP, Keizer HJ, Beijnen JH, Bult A, Underberg WJ. Kaijser GP, et al. Among authors: keizer hj. Anticancer Res. 1996 Sep-Oct;16(5B):3247-57. Anticancer Res. 1996. PMID: 8920799

9

Chromatographic analysis of the enantiomers of ifosfamide and some of its metabolites in plasma and urine.

Kaijser GP, Beijnen JH, Bult A, Keizer HJ, Underberg WJ. Kaijser GP, et al. Among authors: keizer hj. J Chromatogr B Biomed Sci Appl. 1997 Mar 7;690(1-2):131-8. doi: 10.1016/s0378-4347(96)00376-3. J Chromatogr B Biomed Sci Appl. 1997. PMID: 9106037

10

Distribution of ifosfamide and metabolites between plasma and erythrocytes.

Kerbusch T, Herben VM, Jeuken MJ, Ouwerkerk J, Keizer HJ, Beijnen JH. Kerbusch T, et al. Among authors: keizer hj. Biopharm Drug Dispos. 2001 Apr;22(3):99-108. doi: 10.1002/bdd.257. Biopharm Drug Dispos. 2001. PMID: 11745912

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