Coward P - Search Results

1

Conditional expression of a Gi-coupled receptor causes ventricular conduction delay and a lethal cardiomyopathy.

Redfern CH, Degtyarev MY, Kwa AT, Salomonis N, Cotte N, Nanevicz T, Fidelman N, Desai K, Vranizan K, Lee EK, Coward P, Shah N, Warrington JA, Fishman GI, Bernstein D, Baker AJ, Conklin BR. Redfern CH, et al. Among authors: coward p. Proc Natl Acad Sci U S A. 2000 Apr 25;97(9):4826-31. doi: 10.1073/pnas.97.9.4826. Proc Natl Acad Sci U S A. 2000. PMID: 10781088 Free PMC article.

2

Controlling signaling with a specifically designed Gi-coupled receptor.

Coward P, Wada HG, Falk MS, Chan SD, Meng F, Akil H, Conklin BR. Coward P, et al. Proc Natl Acad Sci U S A. 1998 Jan 6;95(1):352-7. doi: 10.1073/pnas.95.1.352. Proc Natl Acad Sci U S A. 1998. PMID: 9419379 Free PMC article.

3

Conditional expression and signaling of a specifically designed Gi-coupled receptor in transgenic mice.

Redfern CH, Coward P, Degtyarev MY, Lee EK, Kwa AT, Hennighausen L, Bujard H, Fishman GI, Conklin BR. Redfern CH, et al. Among authors: coward p. Nat Biotechnol. 1999 Feb;17(2):165-9. doi: 10.1038/6165. Nat Biotechnol. 1999. PMID: 10052353

4

Engineering receptors activated solely by synthetic ligands (RASSLs).

Scearce-Levie K, Coward P, Redfern CH, Conklin BR. Scearce-Levie K, et al. Among authors: coward p. Trends Pharmacol Sci. 2001 Aug;22(8):414-20. doi: 10.1016/s0165-6147(00)01743-0. Trends Pharmacol Sci. 2001. PMID: 11479004

5

Tools for dissecting signaling pathways in vivo: receptors activated solely by synthetic ligands.

Scearce-Levie K, Coward P, Redfern CH, Conklin BR. Scearce-Levie K, et al. Among authors: coward p. Methods Enzymol. 2002;343:232-48. doi: 10.1016/s0076-6879(02)43139-4. Methods Enzymol. 2002. PMID: 11665570 No abstract available.

6

Chimeric G proteins allow a high-throughput signaling assay of Gi-coupled receptors.

Coward P, Chan SD, Wada HG, Humphries GM, Conklin BR. Coward P, et al. Anal Biochem. 1999 Jun 1;270(2):242-8. doi: 10.1006/abio.1999.4061. Anal Biochem. 1999. PMID: 10334841

7

4-Hydroxytamoxifen binds to and deactivates the estrogen-related receptor gamma.

Coward P, Lee D, Hull MV, Lehmann JM. Coward P, et al. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8880-4. doi: 10.1073/pnas.151244398. Epub 2001 Jul 10. Proc Natl Acad Sci U S A. 2001. PMID: 11447273 Free PMC article.

8

In vitro binding and expression studies demonstrate a role for the mouse Sry Q-rich domain in sex determination.

Zhang J, Coward P, Xian M, Lau YF. Zhang J, et al. Among authors: coward p. Int J Dev Biol. 1999 May;43(3):219-27. Int J Dev Biol. 1999. PMID: 10410901

9

Orphan nuclear receptors: from new ligand discovery technologies to novel signaling pathways.

Shiau AK, Coward P, Schwarz M, Lehmann JM. Shiau AK, et al. Among authors: coward p. Curr Opin Drug Discov Devel. 2001 Sep;4(5):575-90. Curr Opin Drug Discov Devel. 2001. PMID: 12825453 Review.

10

Application of an allosteric model to describe the interactions among retinol binding protein 4, transthyretin, and small molecule retinol binding protein 4 ligands.

Coward P, Conn M, Tang J, Xiong F, Menjares A, Reagan JD. Coward P, et al. Anal Biochem. 2009 Jan 15;384(2):312-20. doi: 10.1016/j.ab.2008.09.051. Epub 2008 Oct 12. Anal Biochem. 2009. PMID: 18952041

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