Smith SO - Search Results

1

A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5.

Dragic T, Trkola A, Thompson DA, Cormier EG, Kajumo FA, Maxwell E, Lin SW, Ying W, Smith SO, Sakmar TP, Moore JP. Dragic T, et al. Among authors: smith so. Proc Natl Acad Sci U S A. 2000 May 9;97(10):5639-44. doi: 10.1073/pnas.090576697. Proc Natl Acad Sci U S A. 2000. PMID: 10779565 Free PMC article.

2

Interaction of small molecule inhibitors of HIV-1 entry with CCR5.

Seibert C, Ying W, Gavrilov S, Tsamis F, Kuhmann SE, Palani A, Tagat JR, Clader JW, McCombie SW, Baroudy BM, Smith SO, Dragic T, Moore JP, Sakmar TP. Seibert C, et al. Among authors: smith so. Virology. 2006 May 25;349(1):41-54. doi: 10.1016/j.virol.2006.01.018. Epub 2006 Feb 21. Virology. 2006. PMID: 16494916 Free article.

3

The C9 methyl group of retinal interacts with glycine-121 in rhodopsin.

Han M, Groesbeek M, Sakmar TP, Smith SO. Han M, et al. Among authors: smith so. Proc Natl Acad Sci U S A. 1997 Dec 9;94(25):13442-7. doi: 10.1073/pnas.94.25.13442. Proc Natl Acad Sci U S A. 1997. PMID: 9391044 Free PMC article.

4

Constitutive activation of opsin by mutation of methionine 257 on transmembrane helix 6.

Han M, Smith SO, Sakmar TP. Han M, et al. Among authors: smith so. Biochemistry. 1998 Jun 2;37(22):8253-61. doi: 10.1021/bi980147r. Biochemistry. 1998. PMID: 9609722

5

Magic angle spinning NMR of the protonated retinylidene Schiff base nitrogen in rhodopsin: expression of 15N-lysine- and 13C-glycine-labeled opsin in a stable cell line.

Eilers M, Reeves PJ, Ying W, Khorana HG, Smith SO. Eilers M, et al. Among authors: smith so. Proc Natl Acad Sci U S A. 1999 Jan 19;96(2):487-92. doi: 10.1073/pnas.96.2.487. Proc Natl Acad Sci U S A. 1999. PMID: 9892660 Free PMC article.

6

The effects of amino acid replacements of glycine 121 on transmembrane helix 3 of rhodopsin.

Han M, Lin SW, Smith SO, Sakmar TP. Han M, et al. Among authors: smith so. J Biol Chem. 1996 Dec 13;271(50):32330-6. doi: 10.1074/jbc.271.50.32330. J Biol Chem. 1996. PMID: 8943295 Free article.

7

Functional interaction of transmembrane helices 3 and 6 in rhodopsin. Replacement of phenylalanine 261 by alanine causes reversion of phenotype of a glycine 121 replacement mutant.

Han M, Lin SW, Minkova M, Smith SO, Sakmar TP. Han M, et al. Among authors: smith so. J Biol Chem. 1996 Dec 13;271(50):32337-42. doi: 10.1074/jbc.271.50.32337. J Biol Chem. 1996. PMID: 8943296 Free article.

8

Partial agonist activity of 11-cis-retinal in rhodopsin mutants.

Han M, Lou J, Nakanishi K, Sakmar TP, Smith SO. Han M, et al. Among authors: smith so. J Biol Chem. 1997 Sep 12;272(37):23081-5. doi: 10.1074/jbc.272.37.23081. J Biol Chem. 1997. PMID: 9287308 Free article.

9

Role of the C9 methyl group in rhodopsin activation: characterization of mutant opsins with the artificial chromophore 11-cis-9-demethylretinal.

Han M, Groesbeek M, Smith SO, Sakmar TP. Han M, et al. Among authors: smith so. Biochemistry. 1998 Jan 13;37(2):538-45. doi: 10.1021/bi972060w. Biochemistry. 1998. PMID: 9425074

10

The steric trigger in rhodopsin activation.

Shieh T, Han M, Sakmar TP, Smith SO. Shieh T, et al. Among authors: smith so. J Mol Biol. 1997 Jun 13;269(3):373-84. doi: 10.1006/jmbi.1997.1035. J Mol Biol. 1997. PMID: 9199406 Free article.

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