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The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity.
Yamauchi T, Kamon J, Waki H, Terauchi Y, Kubota N, Hara K, Mori Y, Ide T, Murakami K, Tsuboyama-Kasaoka N, Ezaki O, Akanuma Y, Gavrilova O, Vinson C, Reitman ML, Kagechika H, Shudo K, Yoda M, Nakano Y, Tobe K, Nagai R, Kimura S, Tomita M, Froguel P, Kadowaki T. Yamauchi T, et al. Among authors: hara k. Nat Med. 2001 Aug;7(8):941-6. doi: 10.1038/90984. Nat Med. 2001. PMID: 11479627
The role of PPARgamma as a thrifty gene both in mice and humans.
Hara K, Kubota N, Tobe K, Terauchi Y, Miki H, Komeda K, Tamemoto H, Yamauchi T, Hagura R, Ito C, Akanuma Y, Kadowaki T. Hara K, et al. Br J Nutr. 2000 Dec;84 Suppl 2:S235-9. doi: 10.1079/096582197388608. Br J Nutr. 2000. PMID: 11242476
The Pro12 -->Ala substitution in PPAR-gamma is associated with resistance to development of diabetes in the general population: possible involvement in impairment of insulin secretion in individuals with type 2 diabetes.
Mori H, Ikegami H, Kawaguchi Y, Seino S, Yokoi N, Takeda J, Inoue I, Seino Y, Yasuda K, Hanafusa T, Yamagata K, Awata T, Kadowaki T, Hara K, Yamada N, Gotoda T, Iwasaki N, Iwamoto Y, Sanke T, Nanjo K, Oka Y, Matsutani A, Maeda E, Kasuga M. Mori H, et al. Among authors: hara k. Diabetes. 2001 Apr;50(4):891-4. doi: 10.2337/diabetes.50.4.891. Diabetes. 2001. PMID: 11289058
4,326 results