Scott MT - Search Results

1

Reversible phosphorylation at the C-terminal regulatory domain of p21(Waf1/Cip1) modulates proliferating cell nuclear antigen binding.

Scott MT, Morrice N, Ball KL. Scott MT, et al. J Biol Chem. 2000 Apr 14;275(15):11529-37. doi: 10.1074/jbc.275.15.11529. J Biol Chem. 2000. PMID: 10753973 Free article.

2

PDK1-dependent activation of atypical PKC leads to degradation of the p21 tumour modifier protein.

Scott MT, Ingram A, Ball KL. Scott MT, et al. EMBO J. 2002 Dec 16;21(24):6771-80. doi: 10.1093/emboj/cdf684. EMBO J. 2002. PMID: 12485998 Free PMC article.

3

Allosteric effects mediate CHK2 phosphorylation of the p53 transactivation domain.

Craig A, Scott M, Burch L, Smith G, Ball K, Hupp T. Craig A, et al. EMBO Rep. 2003 Aug;4(8):787-92. doi: 10.1038/sj.embor.embor901. EMBO Rep. 2003. PMID: 12897801 Free PMC article.

4

A conserved proliferating cell nuclear antigen-interacting protein sequence in Chk1 is required for checkpoint function.

Scorah J, Dong MQ, Yates JR 3rd, Scott M, Gillespie D, McGowan CH. Scorah J, et al. J Biol Chem. 2008 Jun 20;283(25):17250-9. doi: 10.1074/jbc.M800369200. Epub 2008 Apr 30. J Biol Chem. 2008. PMID: 18448427 Free PMC article.

5

Phage-peptide display identifies the interferon-responsive, death-activated protein kinase family as a novel modifier of MDM2 and p21WAF1.

Burch LR, Scott M, Pohler E, Meek D, Hupp T. Burch LR, et al. J Mol Biol. 2004 Mar 12;337(1):115-28. doi: 10.1016/j.jmb.2003.10.081. J Mol Biol. 2004. PMID: 15001356

6

The MDM2 ubiquitination signal in the DNA-binding domain of p53 forms a docking site for calcium calmodulin kinase superfamily members.

Craig AL, Chrystal JA, Fraser JA, Sphyris N, Lin Y, Harrison BJ, Scott MT, Dornreiter I, Hupp TR. Craig AL, et al. Among authors: scott mt. Mol Cell Biol. 2007 May;27(9):3542-55. doi: 10.1128/MCB.01595-06. Epub 2007 Mar 5. Mol Cell Biol. 2007. PMID: 17339337 Free PMC article.

7

Chk1 C-terminal regulatory phosphorylation mediates checkpoint activation by de-repression of Chk1 catalytic activity.

Walker M, Black EJ, Oehler V, Gillespie DA, Scott MT. Walker M, et al. Among authors: scott mt. Oncogene. 2009 Jun 18;28(24):2314-23. doi: 10.1038/onc.2009.102. Epub 2009 May 4. Oncogene. 2009. PMID: 19421147 Free PMC article.

8

p21(WAF1) is component of a positive feedback loop that maintains the p53 transcriptional program.

Pang LY, Scott M, Hayward RL, Mohammed H, Whitelaw CB, Smith GC, Hupp TR. Pang LY, et al. Cell Cycle. 2011 Mar 15;10(6):932-50. doi: 10.4161/cc.10.6.15012. Epub 2011 Mar 15. Cell Cycle. 2011. PMID: 21368573 Free article.

9

Akt/PKB suppresses DNA damage processing and checkpoint activation in late G2.

Xu N, Hegarat N, Black EJ, Scott MT, Hochegger H, Gillespie DA. Xu N, et al. Among authors: scott mt. J Cell Biol. 2010 Aug 9;190(3):297-305. doi: 10.1083/jcb.201003004. Epub 2010 Aug 2. J Cell Biol. 2010. PMID: 20679434 Free PMC article.

10

Chk1 is required for spindle checkpoint function.

Zachos G, Black EJ, Walker M, Scott MT, Vagnarelli P, Earnshaw WC, Gillespie DA. Zachos G, et al. Among authors: scott mt. Dev Cell. 2007 Feb;12(2):247-60. doi: 10.1016/j.devcel.2007.01.003. Dev Cell. 2007. PMID: 17276342 Free PMC article.

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