DeFea KA - Search Results

1

beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2.

DeFea KA, Zalevsky J, Thoma MS, Déry O, Mullins RD, Bunnett NW. DeFea KA, et al. J Cell Biol. 2000 Mar 20;148(6):1267-81. doi: 10.1083/jcb.148.6.1267. J Cell Biol. 2000. PMID: 10725339 Free PMC article.

2

The proliferative and antiapoptotic effects of substance P are facilitated by formation of a beta -arrestin-dependent scaffolding complex.

DeFea KA, Vaughn ZD, O'Bryan EM, Nishijima D, Déry O, Bunnett NW. DeFea KA, et al. Proc Natl Acad Sci U S A. 2000 Sep 26;97(20):11086-91. doi: 10.1073/pnas.190276697. Proc Natl Acad Sci U S A. 2000. PMID: 10995467 Free PMC article.

3

Protein kinase C-mediated desensitization of the neurokinin 1 receptor.

Déry O, Defea KA, Bunnett NW. Déry O, et al. Among authors: defea ka. Am J Physiol Cell Physiol. 2001 May;280(5):C1097-106. doi: 10.1152/ajpcell.2001.280.5.C1097. Am J Physiol Cell Physiol. 2001. PMID: 11287322 Free article.

4

Smoothened determines β-arrestin-mediated removal of the G protein-coupled receptor Gpr161 from the primary cilium.

Pal K, Hwang SH, Somatilaka B, Badgandi H, Jackson PK, DeFea K, Mukhopadhyay S. Pal K, et al. J Cell Biol. 2016 Mar 28;212(7):861-75. doi: 10.1083/jcb.201506132. Epub 2016 Mar 21. J Cell Biol. 2016. PMID: 27002170 Free PMC article.

5

Differential effects of beta-arrestins on the internalization, desensitization and ERK1/2 activation downstream of protease activated receptor-2.

Kumar P, Lau CS, Mathur M, Wang P, DeFea KA. Kumar P, et al. Among authors: defea ka. Am J Physiol Cell Physiol. 2007 Jul;293(1):C346-57. doi: 10.1152/ajpcell.00010.2007. Epub 2007 Apr 18. Am J Physiol Cell Physiol. 2007. PMID: 17442737 Free article.

6

Beta-arrestin multimers: does a crowd help or hinder function?

DeFea KA. DeFea KA. Biochem J. 2008 Jul 1;413(1):e1-3. doi: 10.1042/BJ20081009. Biochem J. 2008. PMID: 18537791

7

A beta-arrestin-dependent scaffold is associated with prolonged MAPK activation in pseudopodia during protease-activated receptor-2-induced chemotaxis.

Ge L, Ly Y, Hollenberg M, DeFea K. Ge L, et al. J Biol Chem. 2003 Sep 5;278(36):34418-26. doi: 10.1074/jbc.M300573200. Epub 2003 Jun 23. J Biol Chem. 2003. PMID: 12821670 Free article.

8

In vivo and in vitro Characterization of a Partial Mu Opioid Receptor Agonist, NKTR-181, Supports Future Therapeutic Development.

Lee AS, Tiwari S, Bishop I, Matossian V, Romaneschi N, Miyazaki T, VanderVeen L, Zalevsky J, DeFea K, Cahill CM, Walwyn WM. Lee AS, et al. Front Pain Res (Lausanne). 2021 Aug 23;2:695962. doi: 10.3389/fpain.2021.695962. eCollection 2021. Front Pain Res (Lausanne). 2021. PMID: 35295409 Free PMC article.

9

Protease-activated receptor-2 simultaneously directs beta-arrestin-1-dependent inhibition and Galphaq-dependent activation of phosphatidylinositol 3-kinase.

Wang P, DeFea KA. Wang P, et al. Among authors: defea ka. Biochemistry. 2006 Aug 8;45(31):9374-85. doi: 10.1021/bi0602617. Biochemistry. 2006. PMID: 16878972

10

Beta-arrestin inhibits CAMKKbeta-dependent AMPK activation downstream of protease-activated-receptor-2.

Wang P, Jiang Y, Wang Y, Shyy JY, DeFea KA. Wang P, et al. Among authors: defea ka. BMC Biochem. 2010 Sep 21;11:36. doi: 10.1186/1471-2091-11-36. BMC Biochem. 2010. PMID: 20858278 Free PMC article.

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