Macdonald N - Search Results

1

Apoptosis and proliferation in nongenotoxic carcinogenesis: species differences and role of PPARalpha.

Roberts RA, James NH, Hasmall SC, Holden PR, Lambe K, Macdonald N, West D, Woodyatt NJ, Whitcome D. Roberts RA, et al. Among authors: macdonald n. Toxicol Lett. 2000 Mar 15;112-113:49-57. doi: 10.1016/s0378-4274(99)00243-x. Toxicol Lett. 2000. PMID: 10720712 Review.

2

Peroxisome proliferator-activated receptor-alpha and the pleiotropic responses to peroxisome proliferators.

Tugwood JD, Aldridge TC, Lambe KG, Macdonald N, Woodyatt NJ. Tugwood JD, et al. Among authors: macdonald n. Arch Toxicol Suppl. 1998;20:377-86. doi: 10.1007/978-3-642-46856-8_33. Arch Toxicol Suppl. 1998. PMID: 9442309 No abstract available.

3

Evidence for the suppression of apoptosis by the peroxisome proliferator activated receptor alpha (PPAR alpha).

Roberts RA, James NH, Woodyatt NJ, Macdonald N, Tugwood JD. Roberts RA, et al. Among authors: macdonald n. Carcinogenesis. 1998 Jan;19(1):43-8. doi: 10.1093/carcin/19.1.43. Carcinogenesis. 1998. PMID: 9472691

4

Peroxisome proliferator-activated receptor (PPAR) alpha-regulated growth responses and their importance to hepatocarcinogenesis.

James NH, Gill JH, Brindle R, Woodyatt NJ, Macdonald N, Rolfe M, Hasmall SC, Tugwood JD, Holden PR, Roberts RA. James NH, et al. Among authors: macdonald n. Toxicol Lett. 1998 Dec 28;102-103:91-6. doi: 10.1016/s0378-4274(98)00291-4. Toxicol Lett. 1998. PMID: 10022238 Review.

5

Addition of peroxisome proliferator-activated receptor alpha to guinea pig hepatocytes confers increased responsiveness to peroxisome proliferators.

Macdonald N, Holden PR, Roberts RA. Macdonald N, et al. Cancer Res. 1999 Oct 1;59(19):4776-80. Cancer Res. 1999. PMID: 10519382

6

Induction of DNA replication by peroxisome proliferators is independent of both tumour necrosis factor (alpha) priming and EGF-receptor tyrosine kinase activity.

Chevalier S, Macdonald N, Roberts RA. Chevalier S, et al. Among authors: macdonald n. J Cell Sci. 1999 Dec;112 ( Pt 24):4785-91. doi: 10.1242/jcs.112.24.4785. J Cell Sci. 1999. PMID: 10574725

7

Species differences in sequence and activity of the peroxisome proliferator response element (PPRE) within the acyl CoA oxidase gene promoter.

Lambe KG, Woodyatt NJ, Macdonald N, Chevalier S, Roberts RA. Lambe KG, et al. Among authors: macdonald n. Toxicol Lett. 1999 Oct 29;110(1-2):119-27. doi: 10.1016/s0378-4274(99)00151-4. Toxicol Lett. 1999. PMID: 10593603

8

Suppression of apoptosis and induction of DNA synthesis in vitro by the phthalate plasticizers monoethylhexylphthalate (MEHP) and diisononylphthalate (DINP): a comparison of rat and human hepatocytes in vitro.

Hasmall SC, James NH, Macdonald N, West D, Chevalier S, Cosulich SC, Roberts RA. Hasmall SC, et al. Among authors: macdonald n. Arch Toxicol. 1999 Nov;73(8-9):451-6. doi: 10.1007/s002040050634. Arch Toxicol. 1999. PMID: 10650916

9

Suppression of mouse hepatocyte apoptosis by peroxisome proliferators: role of PPARalpha and TNFalpha.

Hasmall SC, James NH, Macdonald N, Gonzalez FJ, Peters JM, Roberts RA. Hasmall SC, et al. Among authors: macdonald n. Mutat Res. 2000 Mar 17;448(2):193-200. doi: 10.1016/s0027-5107(99)00236-5. Mutat Res. 2000. PMID: 10725472

10

Species differences in response to diethylhexylphthalate: suppression of apoptosis, induction of DNA synthesis and peroxisome proliferator activated receptor alpha-mediated gene expression.

Hasmall SC, James NH, Macdonald N, Soames AR, Roberts RA. Hasmall SC, et al. Among authors: macdonald n. Arch Toxicol. 2000 Apr;74(2):85-91. doi: 10.1007/s002040050657. Arch Toxicol. 2000. PMID: 10839475

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