McBride A - Search Results

1

2-Substituted tryptamines: agents with selectivity for 5-HT(6) serotonin receptors.

Glennon RA, Lee M, Rangisetty JB, Dukat M, Roth BL, Savage JE, McBride A, Rauser L, Hufeisen S, Lee DK. Glennon RA, et al. Among authors: mcbride a. J Med Chem. 2000 Mar 9;43(5):1011-8. doi: 10.1021/jm990550b. J Med Chem. 2000. PMID: 10715164

2

Evidence for possible involvement of 5-HT(2B) receptors in the cardiac valvulopathy associated with fenfluramine and other serotonergic medications.

Rothman RB, Baumann MH, Savage JE, Rauser L, McBride A, Hufeisen SJ, Roth BL. Rothman RB, et al. Among authors: mcbride a. Circulation. 2000 Dec 5;102(23):2836-41. doi: 10.1161/01.cir.102.23.2836. Circulation. 2000. PMID: 11104741

3

Design, synthesis and in vivo study of novel pyrrolidine-based 11β-HSD1 inhibitors for age-related cognitive dysfunction.

Leiva R, Griñan-Ferré C, Seira C, Valverde E, McBride A, Binnie M, Pérez B, Luque FJ, Pallàs M, Bidon-Chanal A, Webster SP, Vázquez S. Leiva R, et al. Among authors: mcbride a. Eur J Med Chem. 2017 Oct 20;139:412-428. doi: 10.1016/j.ejmech.2017.08.003. Epub 2017 Aug 4. Eur J Med Chem. 2017. PMID: 28818766 Free article.

4

Development of a Series of Kynurenine 3-Monooxygenase Inhibitors Leading to a Clinical Candidate for the Treatment of Acute Pancreatitis.

Walker AL, Ancellin N, Beaufils B, Bergeal M, Binnie M, Bouillot A, Clapham D, Denis A, Haslam CP, Holmes DS, Hutchinson JP, Liddle J, McBride A, Mirguet O, Mowat CG, Rowland P, Tiberghien N, Trottet L, Uings I, Webster SP, Zheng X, Mole DJ. Walker AL, et al. Among authors: mcbride a. J Med Chem. 2017 Apr 27;60(8):3383-3404. doi: 10.1021/acs.jmedchem.7b00055. Epub 2017 Apr 11. J Med Chem. 2017. PMID: 28398044 Free article.

5

The discovery of potent and selective kynurenine 3-monooxygenase inhibitors for the treatment of acute pancreatitis.

Liddle J, Beaufils B, Binnie M, Bouillot A, Denis AA, Hann MM, Haslam CP, Holmes DS, Hutchinson JP, Kranz M, McBride A, Mirguet O, Mole DJ, Mowat CG, Pal S, Rowland P, Trottet L, Uings IJ, Walker AL, Webster SP. Liddle J, et al. Among authors: mcbride a. Bioorg Med Chem Lett. 2017 May 1;27(9):2023-2028. doi: 10.1016/j.bmcl.2017.02.078. Epub 2017 Mar 9. Bioorg Med Chem Lett. 2017. PMID: 28336141 Free article.

6

Novel 11β-HSD1 inhibitors: C-1 versus C-2 substitution and effect of the introduction of an oxygen atom in the adamantane scaffold.

Leiva R, Seira C, McBride A, Binnie M, Luque FJ, Bidon-Chanal A, Webster SP, Vázquez S. Leiva R, et al. Among authors: mcbride a. Bioorg Med Chem Lett. 2015 Oct 1;25(19):4250-3. doi: 10.1016/j.bmcl.2015.07.097. Epub 2015 Aug 5. Bioorg Med Chem Lett. 2015. PMID: 26306982 Free article.

7

A series of 2(Z)-2-benzylidene-6,7-dihydroxybenzofuran-3[2H]-ones as inhibitors of chorismate synthase.

Thomas MG, Lawson C, Allanson NM, Leslie BW, Bottomley JR, McBride A, Olusanya OA. Thomas MG, et al. Among authors: mcbride a. Bioorg Med Chem Lett. 2003 Feb 10;13(3):423-6. doi: 10.1016/s0960-894x(02)00957-5. Bioorg Med Chem Lett. 2003. PMID: 12565943

8

Searching for novel applications of the benzohomoadamantane scaffold in medicinal chemistry: Synthesis of novel 11β-HSD1 inhibitors.

Valverde E, Seira C, McBride A, Binnie M, Luque FJ, Webster SP, Bidon-Chanal A, Vázquez S. Valverde E, et al. Among authors: mcbride a. Bioorg Med Chem. 2015 Dec 15;23(24):7607-17. doi: 10.1016/j.bmc.2015.11.004. Epub 2015 Nov 5. Bioorg Med Chem. 2015. PMID: 26596711

9

Exploring N-acyl-4-azatetracyclo[5.3.2.0^2,6.0^8,10]dodec-11-enes as 11β-HSD1 Inhibitors.

Leiva R, McBride A, Binnie M, Webster SP, Vázquez S. Leiva R, et al. Among authors: mcbride a. Molecules. 2018 Feb 28;23(3):536. doi: 10.3390/molecules23030536. Molecules. 2018. PMID: 29495550 Free PMC article.

10

Cognitive and Disease-Modifying Effects of 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibition in Male Tg2576 Mice, a Model of Alzheimer's Disease.

Sooy K, Noble J, McBride A, Binnie M, Yau JL, Seckl JR, Walker BR, Webster SP. Sooy K, et al. Among authors: mcbride a. Endocrinology. 2015 Dec;156(12):4592-603. doi: 10.1210/en.2015-1395. Epub 2015 Aug 25. Endocrinology. 2015. PMID: 26305888 Free PMC article.

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