Tran M - Search Results

1

Synthesis of N-substituted 4-(4-hydroxyphenyl)piperidines, 4-(4-hydroxybenzyl)piperidines, and (+/-)-3-(4-hydroxyphenyl)pyrrolidines: selective antagonists at the 1A/2B NMDA receptor subtype.

Guzikowski AP, Tamiz AP, Acosta-Burruel M, Hong-Bae S, Cai SX, Hawkinson JE, Keana JF, Kesten SR, Shipp CT, Tran M, Whittemore ER, Woodward RM, Wright JL, Zhou ZL. Guzikowski AP, et al. Among authors: tran m. J Med Chem. 2000 Mar 9;43(5):984-94. doi: 10.1021/jm990428c. J Med Chem. 2000. PMID: 10715162

2

Synthesis and SAR of novel di- and trisubstituted 1,4-dihydroquinoxaline-2,3-diones related to licostinel (Acea 1021) as NMDA/glycine site antagonists.

Zhou ZL, Kher SM, Cai SX, Whittemore ER, Espitia SA, Hawkinson JE, Tran M, Woodward RM, Weber E, Keana JF. Zhou ZL, et al. Among authors: tran m. Bioorg Med Chem. 2003 Apr 17;11(8):1769-80. doi: 10.1016/s0968-0896(03)00059-2. Bioorg Med Chem. 2003. PMID: 12659763

3

Analogs of 3-hydroxy-1H-1-benzazepine-2,5-dione: structure-activity relationship at N-methyl-D-aspartate receptor glycine sites.

Guzikowski AP, Cai SX, Espitia SA, Hawkinson JE, Huettner JE, Nogales DF, Tran M, Woodward RM, Weber E, Keana JF. Guzikowski AP, et al. Among authors: tran m. J Med Chem. 1996 Nov 8;39(23):4643-53. doi: 10.1021/jm960479z. J Med Chem. 1996. PMID: 8917653

4

Structure-activity relationships of alkyl- and alkoxy-substituted 1,4-dihydroquinoxaline-2,3-diones: potent and systemically active antagonists for the glycine site of the NMDA receptor.

Cai SX, Kher SM, Zhou ZL, Ilyin V, Espitia SA, Tran M, Hawkinson JE, Woodward RM, Weber E, Keana JF. Cai SX, et al. Among authors: tran m. J Med Chem. 1997 Feb 28;40(5):730-8. doi: 10.1021/jm960654b. J Med Chem. 1997. PMID: 9057859

5

5-(N-oxyaza)-7-substituted-1,4-dihydroquinoxaline-2,3-diones: novel, systemically active and broad spectrum antagonists for NMDA/glycine, AMPA, and kainate receptors.

Cai SX, Huang JC, Espitia SA, Tran M, Ilyin VI, Hawkinson JE, Woodward RM, Weber E, Keana JF. Cai SX, et al. Among authors: tran m. J Med Chem. 1997 Oct 24;40(22):3679-86. doi: 10.1021/jm970396y. J Med Chem. 1997. PMID: 9357535

6

4-Hydroxy-1-[2-(4-hydroxyphenoxy)ethyl]-4-(4-methylbenzyl)piperidine: a novel, potent, and selective NR1/2B NMDA receptor antagonist.

Zhou ZL, Cai SX, Whittemore ER, Konkoy CS, Espitia SA, Tran M, Rock DM, Coughenour LL, Hawkinson JE, Boxer PA, Bigge CF, Wise LD, Weber E, Woodward RM, Keana JF. Zhou ZL, et al. Among authors: tran m. J Med Chem. 1999 Jul 29;42(15):2993-3000. doi: 10.1021/jm990246i. J Med Chem. 1999. PMID: 10425109

7

Synthesis and SAR of 5-, 6-, 7- and 8-aza analogues of 3-aryl-4-hydroxyquinolin-2(1H)-one as NMDA/glycine site antagonists.

Zhou ZL, Navratil JM, Cai SX, Whittemore ER, Espitia SA, Hawkinson JE, Tran M, Woodward RM, Weber E, Keana JF. Zhou ZL, et al. Among authors: tran m. Bioorg Med Chem. 2001 Aug;9(8):2061-71. doi: 10.1016/s0968-0896(01)00115-8. Bioorg Med Chem. 2001. PMID: 11504642

8

Pharmacology of ACEA-1416: a potent systemically active NMDA receptor glycine site antagonist.

Ilyin VI, Whittemore ER, Tran M, Shen KZ, Cai SX, Kher SM, Keana JF, Weber E, Woodward RM. Ilyin VI, et al. Among authors: tran m. Eur J Pharmacol. 1996 Aug 29;310(2-3):107-14. doi: 10.1016/0014-2999(96)00370-6. Eur J Pharmacol. 1996. PMID: 8884205

9

Design, synthesis, and activity of a series of arylpyrid-3-ylmethanones as type I positive allosteric modulators of α7 nicotinic acetylcholine receptors.

Hogenkamp DJ, Ford-Hutchinson TA, Li WY, Whittemore ER, Yoshimura RF, Tran MB, Johnstone TB, Bascom GD, Rollins H, Lu L, Gee KW. Hogenkamp DJ, et al. J Med Chem. 2013 Nov 14;56(21):8352-65. doi: 10.1021/jm400704g. Epub 2013 Oct 30. J Med Chem. 2013. PMID: 24098954 Free PMC article.

10

Enaminone amides as novel orally active GABAA receptor modulators.

Hogenkamp DJ, Johnstone TB, Huang JC, Li WY, Tran M, Whittemore ER, Bagnera RE, Gee KW. Hogenkamp DJ, et al. Among authors: tran m. J Med Chem. 2007 Jul 12;50(14):3369-79. doi: 10.1021/jm070083v. Epub 2007 Jun 16. J Med Chem. 2007. PMID: 17571865

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