Wexler RR - Search Results

1

The de novo design and synthesis of cyclic urea inhibitors of factor Xa: optimization of the S4 ligand.

Galemmo RA Jr, Wells BL, Rossi KA, Alexander RS, Dominguez C, Maduskuie TP, Stouten PF, Wright MR, Aungst BJ, Wong PC, Knabb RM, Wexler RR. Galemmo RA Jr, et al. Among authors: wexler rr. Bioorg Med Chem Lett. 2000 Feb 7;10(3):301-4. doi: 10.1016/s0960-894x(99)00688-5. Bioorg Med Chem Lett. 2000. PMID: 10698459

2

Rationale for the chemical development of angiotensin II receptor antagonists.

Wexler RR, Carini DJ, Duncia JV, Johnson AL, Wells GJ, Chiu AT, Wong PC, Timmermans PB. Wexler RR, et al. Am J Hypertens. 1992 Dec;5(12 Pt 2):209S-220S. doi: 10.1093/ajh/5.12.209s. Am J Hypertens. 1992. PMID: 1290616 Review.

3

The discovery of DuP 753, a potent, orally active nonpeptide angiotensin II receptor antagonist.

Duncia JV, Carini DJ, Chiu AT, Johnson AL, Price WA, Wong PC, Wexler RR, Timmermans PB. Duncia JV, et al. Among authors: wexler rr. Med Res Rev. 1992 Mar;12(2):149-91. doi: 10.1002/med.2610120203. Med Res Rev. 1992. PMID: 1619965 Review. No abstract available.

4

The discovery of a new class of highly specific nonpeptide angiotensin II receptor antagonists.

Timmermans PB, Carini DJ, Chiu AT, Duncia JV, Price WA Jr, Wells GJ, Wong PC, Johnson AL, Wexler RR. Timmermans PB, et al. Among authors: wexler rr. Am J Hypertens. 1991 Apr;4(4 Pt 2):275S-281S. doi: 10.1093/ajh/4.4.275s. Am J Hypertens. 1991. PMID: 1854452 Review.

5

In vitro pharmacology of DuP 753.

Chiu AT, McCall DE, Price WA Jr, Wong PC, Carini DJ, Duncia JV, Wexler RR, Yoo SE, Johnson AL, Timmermans PB. Chiu AT, et al. Among authors: wexler rr. Am J Hypertens. 1991 Apr;4(4 Pt 2):282S-287S. doi: 10.1093/ajh/4.4.282s. Am J Hypertens. 1991. PMID: 1854453 Review.

6

In vivo pharmacology of DuP 753.

Wong PC, Price WA Jr, Chiu AT, Duncia JV, Carini DJ, Wexler RR, Johnson AL, Timmermans PB. Wong PC, et al. Among authors: wexler rr. Am J Hypertens. 1991 Apr;4(4 Pt 2):288S-298S. doi: 10.1093/ajh/4.4.288s. Am J Hypertens. 1991. PMID: 1854454 Review.

7

Angiotensin II receptor heterogeneity.

Herblin WF, Chiu AT, McCall DE, Ardecky RJ, Carini DJ, Duncia JV, Pease LJ, Wong PC, Wexler RR, Johnson AL, et al. Herblin WF, et al. Among authors: wexler rr. Am J Hypertens. 1991 Apr;4(4 Pt 2):299S-302S. doi: 10.1093/ajh/4.4.299s. Am J Hypertens. 1991. PMID: 1854455

8

Angiotensin II receptor antagonists. From discovery to antihypertensive drugs.

Timmermans PB, Carini DJ, Chiu AT, Duncia JV, Price WA Jr, Wells GJ, Wong PC, Wexler RR, Johnson AL. Timmermans PB, et al. Among authors: wexler rr. Hypertension. 1991 Nov;18(5 Suppl):III136-42. doi: 10.1161/01.hyp.18.5_suppl.iii136. Hypertension. 1991. PMID: 1937677 Review.

9

Pharmacology of DuP 532, a selective and noncompetitive AT1 receptor antagonist.

Wong PC, Hart SD, Chiu AT, Herblin WF, Carini DJ, Smith RD, Wexler RR, Timmermans PB. Wong PC, et al. Among authors: wexler rr. J Pharmacol Exp Ther. 1991 Nov;259(2):861-70. J Pharmacol Exp Ther. 1991. PMID: 1941632

10

Nonpeptide angiotensin II receptor antagonists: a novel class of antihypertensive agents.

Timmermans PB, Carini DJ, Chiu AT, Duncia JV, Price WA Jr, Wells GJ, Wong PC, Wexler RR, Johnson AL. Timmermans PB, et al. Among authors: wexler rr. Blood Vessels. 1990;27(2-5):295-300. doi: 10.1159/000158821. Blood Vessels. 1990. PMID: 1978694 Review.

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