Cleavage of surfactant-incorporating fibrin by different fibrinolytic agents. Kinetics of lysis and rescue of surface activity.
Günther A, Markart P, Kalinowski M, Ruppert C, Grimminger F, Seeger W.
Günther A, et al.
Am J Respir Cell Mol Biol. 1999 Dec;21(6):738-45. doi: 10.1165/ajrcmb.21.6.3514.
Am J Respir Cell Mol Biol. 1999.
PMID: 10572071
Alveofact was employed as a natural surfactant source, and plasminogen was coincorporated into the fibrin matrix at a physiologic ratio to fibrin. ...When incorporated into the fibrin matrix, but not when admixed after clot formation, surfactant inhibited the cleava …
Alveofact was employed as a natural surfactant source, and plasminogen was coincorporated into the fibrin matrix at a physiolo …