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Page 1
Novel benzimidazole derivatives as selective CB2 agonists.
Pagé D, Balaux E, Boisvert L, Liu Z, Milburn C, Tremblay M, Wei Z, Woo S, Luo X, Cheng YX, Yang H, Srivastava S, Zhou F, Brown W, Tomaszewski M, Walpole C, Hodzic L, St-Onge S, Godbout C, Salois D, Payza K. Pagé D, et al. Bioorg Med Chem Lett. 2008 Jul 1;18(13):3695-700. doi: 10.1016/j.bmcl.2008.05.073. Epub 2008 May 22. Bioorg Med Chem Lett. 2008. PMID: 18522867
N,N-Diethyl-4-[(3-hydroxyphenyl)(piperidin-4-yl)amino] benzamide derivatives: the development of diaryl amino piperidines as potent delta opioid receptor agonists with in vivo anti-nociceptive activity in rodent models.
Jones P, Griffin AM, Gawell L, Lavoie R, Delorme D, Roberts E, Brown W, Walpole C, Xiao W, Boulet J, Labarre M, Coupal M, Butterworth J, St-Onge S, Hodzic L, Salois D. Jones P, et al. Bioorg Med Chem Lett. 2009 Nov 1;19(21):5994-8. doi: 10.1016/j.bmcl.2009.09.072. Epub 2009 Sep 22. Bioorg Med Chem Lett. 2009. PMID: 19800791
Inverse agonism by Dmt-Tic analogues and HS 378, a naltrindole analogue.
Labarre M, Butterworth J, St-Onge S, Payza K, Schmidhammer H, Salvadori S, Balboni G, Guerrini R, Bryant SD, Lazarus LH. Labarre M, et al. Eur J Pharmacol. 2000 Oct 6;406(1):R1-3. doi: 10.1016/s0014-2999(00)00636-1. Eur J Pharmacol. 2000. PMID: 11011049
New diarylmethylpiperazines as potent and selective nonpeptidic delta opioid receptor agonists with increased In vitro metabolic stability.
Plobeck N, Delorme D, Wei ZY, Yang H, Zhou F, Schwarz P, Gawell L, Gagnon H, Pelcman B, Schmidt R, Yue SY, Walpole C, Brown W, Zhou E, Labarre M, Payza K, St-Onge S, Kamassah A, Morin PE, Projean D, Ducharme J, Roberts E. Plobeck N, et al. J Med Chem. 2000 Oct 19;43(21):3878-94. doi: 10.1021/jm000228x. J Med Chem. 2000. PMID: 11052793
N,N-Diethyl-4-(phenylpiperidin-4-ylidenemethyl)benzamide: a novel, exceptionally selective, potent delta opioid receptor agonist with oral bioavailability and its analogues.
Wei ZY, Brown W, Takasaki B, Plobeck N, Delorme D, Zhou F, Yang H, Jones P, Gawell L, Gagnon H, Schmidt R, Yue SY, Walpole C, Payza K, St-Onge S, Labarre M, Godbout C, Jakob A, Butterworth J, Kamassah A, Morin PE, Projean D, Ducharme J, Roberts E. Wei ZY, et al. J Med Chem. 2000 Oct 19;43(21):3895-905. doi: 10.1021/jm000229p. J Med Chem. 2000. PMID: 11052794
N-Methyl-3-(tetrahydro-2H-pyran-4-yl)-2,3,4,9-tetrahydro-1H-carbazole-6-carboxamides as a novel class of cannabinoid receptors agonists with low CNS penetration.
Wei Z, Yang H, Liu Z, Tremblay M, Johnstone S, Béha S, Yue SY, Srivastava S, Tomaszewski MJ, Brown W, Walpole C, St-Onge S, Lessard E, Archambault AJ, Groblewski T, Pagé D. Wei Z, et al. Bioorg Med Chem Lett. 2012 Jun 15;22(12):3884-9. doi: 10.1016/j.bmcl.2012.04.128. Epub 2012 May 4. Bioorg Med Chem Lett. 2012. PMID: 22607668
44 results