Camps P - Search Results

1

Huprine X is a novel high-affinity inhibitor of acetylcholinesterase that is of interest for treatment of Alzheimer's disease.

Camps P, Cusack B, Mallender WD, El Achab RE, Morral J, Muñoz-Torrero D, Rosenberry TL. Camps P, et al. Mol Pharmacol. 2000 Feb;57(2):409-17. Mol Pharmacol. 2000. PMID: 10648652

2

Synthesis, in vitro pharmacology, and molecular modeling of very potent tacrine-huperzine A hybrids as acetylcholinesterase inhibitors of potential interest for the treatment of Alzheimer's disease.

Camps P, El Achab R, Görbig DM, Morral J, Muñoz-Torrero D, Badia A, Eladi Baños J, Vivas NM, Barril X, Orozco M, Luque FJ. Camps P, et al. J Med Chem. 1999 Aug 26;42(17):3227-42. doi: 10.1021/jm980620z. J Med Chem. 1999. PMID: 10464010

3

New tacrine-huperzine A hybrids (huprines): highly potent tight-binding acetylcholinesterase inhibitors of interest for the treatment of Alzheimer's disease.

Camps P, El Achab R, Morral J, Muñoz-Torrero D, Badia A, Baños JE, Vivas NM, Barril X, Orozco M, Luque FJ. Camps P, et al. J Med Chem. 2000 Nov 30;43(24):4657-66. doi: 10.1021/jm000980y. J Med Chem. 2000. PMID: 11101357

4

The pharmacology of novel acetylcholinesterase inhibitors, (+/-)-huprines Y and X, on the Torpedo electric organ.

Ros E, Aleu J, Gómez de Aranda I, Muñoz-Torrero D, Camps P, Badia A, Marsal J, Solsona C. Ros E, et al. Among authors: camps p. Eur J Pharmacol. 2001 Jun 8;421(2):77-84. doi: 10.1016/s0014-2999(01)01028-7. Eur J Pharmacol. 2001. PMID: 11399262

5

Cholinergic drugs in pharmacotherapy of Alzheimer's disease.

Camps P, Muñoz-Torrero D. Camps P, et al. Mini Rev Med Chem. 2002 Feb;2(1):11-25. doi: 10.2174/1389557023406638. Mini Rev Med Chem. 2002. PMID: 12369954 Review.

6

Tacrine-huperzine A hybrids (huprines): a new class of highly potent and selective acetylcholinesterase inhibitors of interest for the treatment of Alzheimer's disease.

Camps P, Muñoz-Torrero D. Camps P, et al. Mini Rev Med Chem. 2001 Jul;1(2):163-74. doi: 10.2174/1389557013406972. Mini Rev Med Chem. 2001. PMID: 12369981 Review.

7

Dimeric and hybrid anti-Alzheimer drug candidates.

Muñoz-Torrero D, Camps P. Muñoz-Torrero D, et al. Among authors: camps p. Curr Med Chem. 2006;13(4):399-422. doi: 10.2174/092986706775527974. Curr Med Chem. 2006. PMID: 16475930 Review.

8

Characterisation of the anticholinesterase activity of two new tacrine-huperzine A hybrids.

Alcalá Mdel M, Vivas NM, Hospital S, Camps P, Muñoz-Torrero D, Badia A. Alcalá Mdel M, et al. Among authors: camps p. Neuropharmacology. 2003 May;44(6):749-55. doi: 10.1016/s0028-3908(03)00071-6. Neuropharmacology. 2003. PMID: 12681373

9

Synthesis and pharmacological evaluation of huprine-tacrine heterodimers: subnanomolar dual binding site acetylcholinesterase inhibitors.

Camps P, Formosa X, Muñoz-Torrero D, Petrignet J, Badia A, Clos MV. Camps P, et al. J Med Chem. 2005 Mar 24;48(6):1701-4. doi: 10.1021/jm0496741. J Med Chem. 2005. PMID: 15771413

10

Binding of 13-amidohuprines to acetylcholinesterase: exploring the ligand-induced conformational change of the gly117-gly118 peptide bond in the oxyanion hole.

Camps P, Gómez E, Muñoz-Torrero D, Badia A, Clos MV, Curutchet C, Muñoz-Muriedas J, Luque FJ. Camps P, et al. J Med Chem. 2006 Nov 16;49(23):6833-40. doi: 10.1021/jm060945c. J Med Chem. 2006. PMID: 17154513

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