Cook PD - Search Results

1

Structural origins of the exonuclease resistance of a zwitterionic RNA.

Teplova M, Wallace ST, Tereshko V, Minasov G, Symons AM, Cook PD, Manoharan M, Egli M. Teplova M, et al. Among authors: cook pd. Proc Natl Acad Sci U S A. 1999 Dec 7;96(25):14240-5. doi: 10.1073/pnas.96.25.14240. Proc Natl Acad Sci U S A. 1999. PMID: 10588690 Free PMC article.

2

Crystal structure and improved antisense properties of 2'-O-(2-methoxyethyl)-RNA.

Teplova M, Minasov G, Tereshko V, Inamati GB, Cook PD, Manoharan M, Egli M. Teplova M, et al. Among authors: cook pd. Nat Struct Biol. 1999 Jun;6(6):535-9. doi: 10.1038/9304. Nat Struct Biol. 1999. PMID: 10360355

3

2'-O-[2-[2-(N,N-dimethylamino)ethoxy]ethyl] modified oligonucleotides: symbiosis of charge interaction factors and stereoelectronic effects.

Prhavc M, Prakash TP, Minasov G, Cook PD, Egli M, Manoharan M. Prhavc M, et al. Among authors: cook pd. Org Lett. 2003 Jun 12;5(12):2017-20. doi: 10.1021/ol0340991. Org Lett. 2003. PMID: 12790517

4

MMI linkage modification increases potency and stability of H-ras antisense oligonucleotides.

Cowsert LM, Ohashi CT, Bhat B, Peoc'h D, Symons AM, Cook PD, Manoharan M. Cowsert LM, et al. Among authors: cook pd. Nucleosides Nucleotides. 1999 Jun-Jul;18(6-7):1383-4. doi: 10.1080/07328319908044723. Nucleosides Nucleotides. 1999. PMID: 10474224 No abstract available.

5

Site-specific cross-linking of nucleic acids using the abasic site.

Manoharan M, Andrade LK, Cook PD. Manoharan M, et al. Among authors: cook pd. Org Lett. 1999 Jul 29;1(2):311-4. doi: 10.1021/ol9906209. Org Lett. 1999. PMID: 10822568

6

Chimeric RNA with modified backbones: alternating methylene(methylimino) linked phosphodiester backbone oligonucleotides with 2'-OH and 2'-OMe groups.

Prhavc M, Bhat B, Just G, Cook PD, Manoharan M. Prhavc M, et al. Among authors: cook pd. Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):995-7. doi: 10.1081/NCN-100002476. Nucleosides Nucleotides Nucleic Acids. 2001. PMID: 11563162

7

In vivo fate of phosphorothioate antisense oligodeoxynucleotides: predominant uptake by scavenger receptors on endothelial liver cells.

Bijsterbosch MK, Manoharan M, Rump ET, De Vrueh RL, van Veghel R, Tivel KL, Biessen EA, Bennett CF, Cook PD, van Berkel TJ. Bijsterbosch MK, et al. Among authors: cook pd. Nucleic Acids Res. 1997 Aug 15;25(16):3290-6. doi: 10.1093/nar/25.16.3290. Nucleic Acids Res. 1997. PMID: 9241243 Free PMC article.

8

Synthesis of novel 3'-C-methylene thymidine and 5-methyluridine/cytidine H-phosphonates and phosphonamidites for new backbone modification of oligonucleotides.

An H, Wang T, Maier MA, Manoharan M, Ross BS, Cook PD. An H, et al. Among authors: cook pd. J Org Chem. 2001 Apr 20;66(8):2789-801. doi: 10.1021/jo001699u. J Org Chem. 2001. PMID: 11304203

9

A 2'-O-thiol tether in the ribose moiety of nucleic acids for conjugation chemistry.

Manoharan M, Tivel KL, Ross B, Cook PD. Manoharan M, et al. Among authors: cook pd. Gene. 1994 Nov 4;149(1):147-56. doi: 10.1016/0378-1119(94)90423-5. Gene. 1994. PMID: 7958979

10

Synthesis and electrochemistry of anthraquinone-oligodeoxynucleotide conjugates.

Whittemore NA, Mullenix AN, Inamati GB, Manoharan M, Cook PD, Tuinman AA, Baker DC, Chambers JQ. Whittemore NA, et al. Among authors: cook pd. Bioconjug Chem. 1999 Mar-Apr;10(2):261-70. doi: 10.1021/bc980095i. Bioconjug Chem. 1999. PMID: 10077476

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