Wertman KF - Search Results

1

Efficient discovery of inhibitory ligands for diverse targets from a small combinatorial chemical library of chimeric molecules.

Thorpe DS, Edith Chan AW, Binnie A, Chen LC, Robinson A, Spoonamore J, Rodwell D, Wade S, Wilson S, Ackerman-Berrier M, Yeoman H, Walle S, Wu Q, Wertman KF. Thorpe DS, et al. Among authors: wertman kf. Biochem Biophys Res Commun. 1999 Dec 9;266(1):62-5. doi: 10.1006/bbrc.1999.1775. Biochem Biophys Res Commun. 1999. PMID: 10581165

2

On-bead and solution screening approaches for genomically derived targets. Discovery of surrogate ligands and substrates using combinatorial chemistry libraries.

Thorpe DS, Rossé G, Yeoman H, Wilson S, Willson P, Harlow G, Robinson A, Wertman KF. Thorpe DS, et al. Among authors: wertman kf. Methods Mol Biol. 2002;201:239-63. doi: 10.1385/1-59259-285-6:239. Methods Mol Biol. 2002. PMID: 12357931 No abstract available.

3

Discovery of D-amino-acid-containing ligands with selectide technology.

Lam KS, Lebl M, Krchnak V, Wade S, Abdul-Latif F, Ferguson R, Cuzzocrea C, Wertman K. Lam KS, et al. Gene. 1993 Dec 27;137(1):13-6. doi: 10.1016/0378-1119(93)90245-x. Gene. 1993. PMID: 8282196

4

High-volume cellular screening for anticancer agents with combinatorial chemical libraries: a new methodology.

Salmon SE, Liu-Stevens RH, Zhao Y, Lebl M, Krchñák V, Wertman K, Sepetov N, Lam KS. Salmon SE, et al. Mol Divers. 1996 Oct;2(1-2):57-63. doi: 10.1007/BF01718701. Mol Divers. 1996. PMID: 9238634

5

A versatile platform to analyze low-affinity and transient protein-protein interactions in living cells in real time.

Li YC, Rodewald LW, Hoppmann C, Wong ET, Lebreton S, Safar P, Patek M, Wang L, Wertman KF, Wahl GM. Li YC, et al. Among authors: wertman kf. Cell Rep. 2014 Dec 11;9(5):1946-1958. doi: 10.1016/j.celrep.2014.10.058. Epub 2014 Nov 20. Cell Rep. 2014. PMID: 25464845 Free PMC article.

6

Mapping actin surfaces required for functional interactions in vivo.

Holtzman DA, Wertman KF, Drubin DG. Holtzman DA, et al. Among authors: wertman kf. J Cell Biol. 1994 Jul;126(2):423-32. doi: 10.1083/jcb.126.2.423. J Cell Biol. 1994. PMID: 8034743 Free PMC article.

7

Actin structure and function: roles in mitochondrial organization and morphogenesis in budding yeast and identification of the phalloidin-binding site.

Drubin DG, Jones HD, Wertman KF. Drubin DG, et al. Among authors: wertman kf. Mol Biol Cell. 1993 Dec;4(12):1277-94. doi: 10.1091/mbc.4.12.1277. Mol Biol Cell. 1993. PMID: 8167410 Free PMC article.

8

Genetic evidence for functional interactions between actin noncomplementing (Anc) gene products and actin cytoskeletal proteins in Saccharomyces cerevisiae.

Vinh DB, Welch MD, Corsi AK, Wertman KF, Drubin DG. Vinh DB, et al. Among authors: wertman kf. Genetics. 1993 Oct;135(2):275-86. doi: 10.1093/genetics/135.2.275. Genetics. 1993. PMID: 8243993 Free PMC article.

9

Actin constitution: guaranteeing the right to assemble.

Wertman KF, Drubin DG. Wertman KF, et al. Science. 1992 Oct 30;258(5083):759-60. doi: 10.1126/science.1439782. Science. 1992. PMID: 1439782 No abstract available.

10

Systematic mutational analysis of the yeast ACT1 gene.

Wertman KF, Drubin DG, Botstein D. Wertman KF, et al. Genetics. 1992 Oct;132(2):337-50. doi: 10.1093/genetics/132.2.337. Genetics. 1992. PMID: 1427032 Free PMC article.

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