Siegfried W - Search Results

1

Phenotypes in three pedigrees with autosomal dominant obesity caused by haploinsufficiency mutations in the melanocortin-4 receptor gene.

Sina M, Hinney A, Ziegler A, Neupert T, Mayer H, Siegfried W, Blum WF, Remschmidt H, Hebebrand J. Sina M, et al. Among authors: siegfried w. Am J Hum Genet. 1999 Dec;65(6):1501-7. doi: 10.1086/302660. Am J Hum Genet. 1999. PMID: 10577903 Free PMC article.

2

No evidence for involvement of the calpain-10 gene 'high-risk' haplotype combination for non-insulin-dependent diabetes mellitus in early onset obesity.

Hinney A, Antwerpen B, Geller F, Schäfer H, Siegfried W, Goldschmidt H, Remschmidt H, Ziegler A, Hebebrand J. Hinney A, et al. Among authors: siegfried w. Mol Genet Metab. 2002 Jun;76(2):152-6. doi: 10.1016/s1096-7192(02)00035-5. Mol Genet Metab. 2002. PMID: 12083814

3

Melanocortin-4 receptor gene: case-control study and transmission disequilibrium test confirm that functionally relevant mutations are compatible with a major gene effect for extreme obesity.

Hinney A, Hohmann S, Geller F, Vogel C, Hess C, Wermter AK, Brokamp B, Goldschmidt H, Siegfried W, Remschmidt H, Schäfer H, Gudermann T, Hebebrand J. Hinney A, et al. Among authors: siegfried w. J Clin Endocrinol Metab. 2003 Sep;88(9):4258-67. doi: 10.1210/jc.2003-030233. J Clin Endocrinol Metab. 2003. PMID: 12970296 Free article. Clinical Trial.

4

Further support for linkage of extreme obesity to the obese gene in a study group of obese children and adolescents.

Roth H, Hinney A, Ziegler A, Barth N, Gerber G, Stein K, Brömel T, Mayer H, Siegfried W, Schäfer H, Remschmidt H, Grzeschik KH, Hebebrand J. Roth H, et al. Among authors: siegfried w. Exp Clin Endocrinol Diabetes. 1997;105(6):341-4. doi: 10.1055/s-0029-1211776. Exp Clin Endocrinol Diabetes. 1997. PMID: 9439930

5

Systematic mutation screening of the pro-opiomelanocortin gene: identification of several genetic variants including three different insertions, one nonsense and two missense point mutations in probands of different weight extremes.

Hinney A, Becker I, Heibült O, Nottebom K, Schmidt A, Ziegler A, Mayer H, Siegfried W, Blum WF, Remschmidt H, Hebebrand J. Hinney A, et al. Among authors: siegfried w. J Clin Endocrinol Metab. 1998 Oct;83(10):3737-41. doi: 10.1210/jcem.83.10.5298. J Clin Endocrinol Metab. 1998. PMID: 9768693

6

No evidence for involvement of the leptin gene in anorexia nervosa, bulimia nervosa, underweight or early onset extreme obesity: identification of two novel mutations in the coding sequence and a novel polymorphism in the leptin gene linked upstream region.

Hinney A, Bornscheuer A, Depenbusch M, Mierke B, Tölle A, Middeke K, Ziegler A, Roth H, Gerber G, Zamzow K, Ballauff A, Hamann A, Mayer H, Siegfried W, Lehmkuhl G, Poustka F, Schmidt MH, Hermann H, Herpertz-Dahlmann BM, Fichter M, Remschmidt H, Hebebrand J. Hinney A, et al. Among authors: siegfried w. Mol Psychiatry. 1998 Nov;3(6):539-43. doi: 10.1038/sj.mp.4000394. Mol Psychiatry. 1998. PMID: 9857981

7

Transmission disequilibrium and sequence variants at the leptin receptor gene in extremely obese German children and adolescents.

Roth H, Korn T, Rosenkranz K, Hinney A, Ziegler A, Kunz J, Siegfried W, Mayer H, Hebebrand J, Grzeschik KH. Roth H, et al. Among authors: siegfried w. Hum Genet. 1998 Nov;103(5):540-6. doi: 10.1007/s004390050867. Hum Genet. 1998. PMID: 9860295

8

Several mutations in the melanocortin-4 receptor gene including a nonsense and a frameshift mutation associated with dominantly inherited obesity in humans.

Hinney A, Schmidt A, Nottebom K, Heibült O, Becker I, Ziegler A, Gerber G, Sina M, Görg T, Mayer H, Siegfried W, Fichter M, Remschmidt H, Hebebrand J. Hinney A, et al. Among authors: siegfried w. J Clin Endocrinol Metab. 1999 Apr;84(4):1483-6. doi: 10.1210/jcem.84.4.5728. J Clin Endocrinol Metab. 1999. PMID: 10199800

9

No evidence for involvement of polymorphisms of the dopamine D4 receptor gene in anorexia nervosa, underweight, and obesity.

Hinney A, Schneider J, Ziegler A, Lehmkuhl G, Poustka F, Schmidt MH, Mayer H, Siegfried W, Remschmidt H, Hebebrand J. Hinney A, et al. Among authors: siegfried w. Am J Med Genet. 1999 Dec 15;88(6):594-7. Am J Med Genet. 1999. PMID: 10581473

10

Mutation screen of the brain derived neurotrophic factor gene (BDNF): identification of several genetic variants and association studies in patients with obesity, eating disorders, and attention-deficit/hyperactivity disorder.

Friedel S, Horro FF, Wermter AK, Geller F, Dempfle A, Reichwald K, Smidt J, Brönner G, Konrad K, Herpertz-Dahlmann B, Warnke A, Hemminger U, Linder M, Kiefl H, Goldschmidt HP, Siegfried W, Remschmidt H, Hinney A, Hebebrand J. Friedel S, et al. Among authors: siegfried w. Am J Med Genet B Neuropsychiatr Genet. 2005 Jan 5;132B(1):96-9. doi: 10.1002/ajmg.b.30090. Am J Med Genet B Neuropsychiatr Genet. 2005. PMID: 15457498

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