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Synthesis and properties of 2-(naphthosultamyl)methyl-carbapenems with potent anti-MRSA activity: discovery of L-786,392.
Ratcliffe RW, Wilkening RR, Wildonger KJ, Waddell ST, Santorelli GM, Parker DL Jr, Morgan JD, Blizzard TA, Hammond ML, Heck JV, Huber J, Kohler J, Dorso KL, St Rose E, Sundelof JG, May WJ, Hammond GG. Ratcliffe RW, et al. Among authors: sundelof jg. Bioorg Med Chem Lett. 1999 Mar 8;9(5):679-84. doi: 10.1016/s0960-894x(99)00071-2. Bioorg Med Chem Lett. 1999. PMID: 10201828
Reduced immunotoxicity and preservation of antibacterial activity in a releasable side-chain carbapenem antibiotic.
Rosen H, Hajdu R, Silver L, Kropp H, Dorso K, Kohler J, Sundelof JG, Huber J, Hammond GG, Jackson JJ, Gill CJ, Thompson R, Pelak BA, Epstein-Toney JH, Lankas G, Wilkening RR, Wildonger KJ, Blizzard TA, DiNinno FP, Ratcliffe RW, Heck JV, Kozarich JW, Hammond ML. Rosen H, et al. Among authors: sundelof jg. Science. 1999 Jan 29;283(5402):703-6. doi: 10.1126/science.283.5402.703. Science. 1999. PMID: 9924033
Pharmacokinetics of L-671,329 in rhesus monkeys and DBA/2 mice.
Sundelof JG, Hajdu R, Cleare WJ, Onishi J, Kropp H. Sundelof JG, et al. Antimicrob Agents Chemother. 1992 Mar;36(3):607-10. doi: 10.1128/AAC.36.3.607. Antimicrob Agents Chemother. 1992. PMID: 1622170 Free PMC article.
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